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Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
CRF65_cpx |
|
Relevant Drug
|
NNRTIs |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32345262
|
|
Clinical information
|
Yes
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
BMC infectious diseases |
|
Title
|
Natural presence of the V179D and K103R/V179D mutations associated with resistance to nonnucleoside reverse transcriptase inhibitors in HIV-1 CRF65_cpx strains. |
|
Author
|
Liu Y,Zhang Y,Li H,Wang X,Jia L,Han J,Li T,Li J,Li L |
|
Evidence
|
For example, most of the HIV-1 O group viruses are considered to be naturally resistant to nonnucleoside reverse transcriptase inhibitors (NNRTIs) due to the presence of the Y181C mutation.
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|
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HIV Mutation Detail Information