|
Mutation Information
|
Mutation Site
|
P178R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
B;D |
|
Country
|
Malaysia; Egypt; Hong Kong; Italy; Taiwan |
Literature Information
|
PubMed PMID
|
23658444
|
|
Clinical information
|
Yes
|
|
Disease
|
Occult HBV infection
|
|
Published Year
|
2013 |
|
Journal
|
Journal of virology |
|
Title
|
Specific amino acid substitutions in the S protein prevent its excretion in vitro and may contribute to occult hepatitis B virus infection. |
|
Author
|
Biswas S,Candotti D,Allain JP |
|
Evidence
|
The substitution M75T, Y100S, or P178R was present in 4/6 pattern 2 OBI clones.
|
|
|
HBV Mutation Detail Information