|
Mutation Information
|
Mutation Site
|
I226N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Country
|
Malaysia; Egypt; Hong Kong; Italy; Taiwan |
Literature Information
|
PubMed PMID
|
23658444
|
|
Clinical information
|
Yes
|
|
Disease
|
Occult HBV infection
|
|
Published Year
|
2013 |
|
Journal
|
Journal of virology |
|
Title
|
Specific amino acid substitutions in the S protein prevent its excretion in vitro and may contribute to occult hepatitis B virus infection. |
|
Author
|
Biswas S,Candotti D,Allain JP |
|
Evidence
|
Eight of the selected substitutions were unique to the pattern 2 sequences studied (M75T, P105R, K160N, W165R, L176P, W182C, V184A, and I226N), whereas one (S167L) and six (Y100S, P111S, G112E, G119E, S154P, and P178R) were also present in OBI pattern 1 and pattern 3 sequences, respectively.
|
|
|
HBV Mutation Detail Information