|
Mutation Information
|
Mutation Site
|
I150T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Country
|
Malaysia; Egypt; Hong Kong; Italy; Taiwan |
Literature Information
|
PubMed PMID
|
23658444
|
|
Clinical information
|
Yes
|
|
Disease
|
Occult HBV infection
|
|
Published Year
|
2013 |
|
Journal
|
Journal of virology |
|
Title
|
Specific amino acid substitutions in the S protein prevent its excretion in vitro and may contribute to occult hepatitis B virus infection. |
|
Author
|
Biswas S,Candotti D,Allain JP |
|
Evidence
|
In contrast, the substitutions P111S+G112E, G119E, Q129R, I150T, S154P, and W165R introduced into the control M88-cl4 did not substantially affect the HBsAg production pattern (Table 3).
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|
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HBV Mutation Detail Information