|
Mutation Information
|
Mutation Site
|
G145E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Viral Reference
|
X75665;
AB014360;
D50520;
AB112472;
AB112063;
AB111946;
FJ562321;
FJ562246;
AB287327;
AB246341 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
19950231
|
|
Clinical information
|
Yes
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2010 |
|
Journal
|
Journal of medical virology |
|
Title
|
PreS deletion mutations of hepatitis B virus in chronically infected patients with simultaneous seropositivity for hepatitis-B surface antigen and anti-HBS antibodies. |
|
Author
|
Huang X,Qin Y,Zhang P,Tang G,Shi Q,Xu J,Qi F,Shen Q |
|
Evidence
|
Five of 28 samples in Group II had point mutations(8 mutated residues) in the ‘‘a’’ determinant, includingI/T126S, A128D, S132F, T131N, M133T, F134L, andG145E.
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|
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HBV Mutation Detail Information