|
Mutation Information
|
Mutation Site
|
C138Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
Literature Information
|
PubMed PMID
|
10762559
|
|
Clinical information
|
Yes
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2000 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Evolution of hepatitis B virus polymerase gene sequence during famciclovir therapy for chronic hepatitis B. |
|
Author
|
Seignères B,Pichoud C,Ahmed SS,Hantz O,Trépo C,Zoulim F |
|
Evidence
|
Three mutations (M125K, G130R, and C138Y) were located in the “a” determinant of the S protein.
|
|
|
HBV Mutation Detail Information