Mutation Information
Mutation Site
|
272–276 del |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
LMP1 |
Country
|
France |
Literature Information
PubMed PMID
|
27061907
|
Clinical information
|
Yes
|
Disease
|
Extranodal natural killer T-cell lymphoma
|
Published Year
|
2016 |
Journal
|
International journal of cancer |
Title
|
Clonal deleted latent membrane protein 1 variants of Epstein-Barr virus are predominant in European extranodal NK/T lymphomas and disappear during successful treatment. |
Author
|
Halabi MA,Jaccard A,Moulinas R,Bahri R,Al Mouhammad H,Mammari N,Feuillard J,Ranger-Rogez S |
Evidence
|
The second (del15) possessed a 15 bp deletion(amino acid positions 272–276) accompanied by 15 substitutions principally localized in the C terminal area, and the third (del30) had a 30 bp deletion (amino acid positions 343–352) and 18 substitutions with 10 of them situated in the TM domains.
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