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Overview of HTLV1 associated
ID Literature Title Group
1 9971764 Multiple functions for the basic amino acids of the human T-cell leukemia virus type 1 matrix protein in viral transmission.
Mutation
2 9710589 An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300.
Mutation
3 10438454 IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein.
Mutation
4 29695435 Critical Role of the Human T-Cell Leukemia Virus Type 1 Capsid N-Terminal Domain for Gag-Gag Interactions and Virus Particle Assembly.
Mutation
5 26557721 HTLV-1 ORF-I Encoded Proteins and the Regulation of Host Immune Response: Viral Induced Dysregulation of Intracellular Signaling.
Mutation
6 23785214 Human T lymphotropic virus type 1 SU residue 195 plays a role in determining the preferential CD4+ T cell immortalization/transformation tropism.
Mutation
7 22163338 Activation of LTRs from different human endogenous retrovirus (HERV) families by the HTLV-1 tax protein and T-cell activators.
Mutation
8 21552325 NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ.
Mutation
9 20653953 Expression of a protein involved in bone resorption, Dkk1, is activated by HTLV-1 bZIP factor through its activation domain.
Mutation
10 19356250 Induction of p21(CIP1/WAF1) expression by human T-lymphotropic virus type 1 Tax requires transcriptional activation and mRNA stabilization.
Mutation
11 18480461 Intersubunit disulfide isomerization controls membrane fusion of human T-cell leukemia virus Env.
Mutation
12 17535428 HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex.
Mutation
13 12711052 Naturally occurring substitutions of the human T-cell leukemia virus type 1 3' LTR influence strand-transfer reaction.
Mutation
14 11333909 The NH2-terminal domain of the human T-cell leukemia virus type 1 capsid protein is involved in particle formation.
Mutation
15 11080799 Kinase-inducible domain-like region of HTLV type 1 tax is important for NF-kappaB activation.
Mutation
16 11070166 Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling.
Mutation
17 11000222 In vivo analysis of human T-cell leukemia virus type 1 reverse transcription accuracy.
Mutation
18 10766811 p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator-enhancer complex.
Mutation
19 10734308 HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration.
Mutation
20 10698501 Functional impairment of p73 and p51, the p53-related proteins, by the human T-cell leukemia virus type 1 Tax oncoprotein.
Mutation
21 10567539 PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner.
Mutation
22 10343169 Analysis of potential phosphorylation sites in human T cell leukemia virus type 1 Tax.
Mutation
23 8011162 A spontaneous point mutation in the human T-cell leukemia virus type 1 pX gene leads to expression of a novel doubly spliced pX-mRNA that encodes a 25-kD, amino-terminal deleted rex protein.
Mutation
24 8756622 Interaction of the human T-cell lymphotropic virus type 1 tax transactivator with transcription factor IIA.
Mutation
25 8970957 Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat.
Mutation
26 10516045 Amino acid changes at positions 173 and 187 in the human T-cell leukemia virus type 1 surface glycoprotein induce specific neutralizing antibodies.
Mutation
27 11046153 Distinct p300-responsive mechanisms promote caspase-dependent apoptosis by human T-cell lymphotropic virus type 1 Tax protein.
Mutation
28 14645559 The central region of human T-cell leukemia virus type 1 Tax protein contains distinct domains involved in subunit dimerization.
Mutation
29 17577584 An N-terminal glycine-rich sequence contributes to retrovirus trimer of hairpins stability.
Mutation
30 19919707 Phosphorylation regulates human T-cell leukemia virus type 1 Rex function.
Mutation
31 23622267 Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats.
Mutation
32 24284316 Palmitoylation and p8-mediated human T-cell leukemia virus type 1 transmission.
Mutation
33 25319617 Molecular insights on analogs of HIV PR inhibitors toward HTLV-1 PR through QM/MM interactions and molecular dynamics studies: comparative structure analysis of wild and mutant HTLV-1 PR.
Mutation
34 25340740 HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation.
Mutation
35 31299491 The human T-cell leukemia virus type-1 tax oncoprotein dissociates NF-κB p65RelA-Stathmin complexes and causes catastrophic mitotic spindle damage and genomic instability.
Mutation
36 33562087 Biochemical Characterization, Specificity and Inhibition Studies of HTLV-1, HTLV-2, and HTLV-3 Proteases.
Mutation
Contents
Description
Group Note
  • Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
  • VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)