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Overview of HPV associated
ID Literature Title Group
1 10400710 The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300.
Mutation
2 10639310 HPV11 mutant virus-like particles elicit immune responses that neutralize virus and delineate a novel neutralizing domain.
Mutation
3 11336560 Induction of type-specific neutralizing antibodies by capsomeres of human papillomavirus type 33.
Mutation
4 11543887 Determination of the binding affinity of different human papillomavirus E7 proteins for the tumour suppressor pRb by a plate-binding assay.
Mutation
5 12196821 [Modification of HPV type 16 E6 and E7 genes, and analysis of stability and immunogenicity of the modified proteins].
Mutation
6 12239337 Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells.
Mutation
7 12551970 Nuclear entry of high-risk human papillomavirus type 16 E6 oncoprotein occurs via several pathways.
Mutation
8 12565157 DNA replicative functions of highly-expressed, codon-optimized human papillomavirus proteins E1 and E2.
Mutation
9 15767402 Human papillomavirus type 16 E1 E4-induced G2 arrest is associated with cytoplasmic retention of active Cdk1/cyclin B1 complexes.
Mutation
10 16519914 HPV16 E6 natural variants exhibit different activities in functional assays relevant to the carcinogenic potential of E6.
Mutation
11 16800784 The human papillomavirus type 16 E7 protein binds human interferon regulatory factor-9 via a novel PEST domain required for transformation.
Mutation
12 16938363 A deletion and point mutation study of the human papillomavirus type 16 major capsid gene.
Mutation
13 17048111 New HPV-16 European and non-European variants in Central Brazil.
Mutation
14 17452980 hAda3 regulates p14ARF-induced p53 acetylation and senescence.
Mutation
15 17854024 Activities of human papillomavirus 16 E6 natural variants in human keratinocytes.
Mutation
16 18619639 Modification of papillomavirus E2 proteins by the small ubiquitin-like modifier family members (SUMOs).
Mutation
17 18986660 Human papillomavirus 16 E6 variants differ in their dysregulation of human keratinocyte differentiation and apoptosis.
Mutation
18 19015633 A single-codon mutation converts HPV16 E6 oncoprotein into a potential tumor suppressor, which induces p53-dependent senescence of HPV-positive HeLa cervical cancer cells.
Mutation
19 19214230 Two highly conserved cysteine residues in HPV16 L2 form an intramolecular disulfide bond and are critical for infectivity in human keratinocytes.
Mutation
20 20383192 The immortalizing and transforming ability of two common human papillomavirus 16 E6 variants with different prevalences in cervical cancer.
Mutation
21 20572344 [The enhancement of DNA binding ability of a mutated E2 (A338V) protein of HPV-2].
Mutation
22 21672450 Is there a biological plausability for p53 codon 72 polymorphism influence on cervical cancer development?
Mutation
23 21811610 Differentiation-dependent interpentameric disulfide bond stabilizes native human papillomavirus type 16.
Mutation
24 22333459 A point mutation in the DNA-binding domain of HPV-2 E2 protein increases its DNA-binding capacity and reverses its transcriptional regulatory activity on the viral early promoter.
Mutation
25 22571619 Human papillomavirus type 58: the unique role in cervical cancers in East Asia.
Mutation
26 24456830 Replication interference between human papillomavirus types 16 and 18 mediated by heterologous E1 helicases.
Mutation
27 24918586 Roles for human papillomavirus type 16 l1 cysteine residues 161, 229, and 379 in genome encapsidation and capsid stability.
Mutation
28 24928042 The nuclear retention signal of HPV16 L2 protein is essential for incoming viral genome to transverse the trans-Golgi network.
Mutation
29 25096873 Maturation of the human papillomavirus 16 capsid.
Mutation
30 25227848 A novel mutant of human papillomavirus type 18 E6E7 fusion gene and its transforming activity.
Mutation
31 25735347 Mutation detection of E6 and LCR genes from HPV 16 associated with carcinogenesis.
Mutation
32 26318249 The human papillomavirus 16 European-T350G E6 variant can immortalize but not transform keratinocytes in the absence of E7.
Mutation
33 26732286 Enhanced expression of soluble human papillomavirus L1 through coexpression of molecular chaperonin in Escherichia coli.
Mutation
34 27030265 The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC.
Mutation
35 27806689 Functional variants of human papillomavirus type 16 demonstrate host genome integration and transcriptional alterations corresponding to their unique cancer epidemiology.
Mutation
36 27829177 A naturally occurring variant of HPV-16 E7 exerts increased transforming activity through acquisition of an additional phospho-acceptor site.
Mutation
37 28497579 Modulation of basal cell fate during productive and transforming HPV-16 infection is mediated by progressive E6-driven depletion of Notch.
Mutation
38 28794033 Ancient Evolution and Dispersion of Human Papillomavirus 58 Variants.
Mutation
39 28968823 Naturally Occurring Single Amino Acid Substitution in the L1 Major Capsid Protein of Human Papillomavirus Type 16: Alteration of Susceptibility to Antibody-Mediated Neutralization.
Mutation
40 29142126 Human Papillomavirus Replication Regulation by Acetylation of a Conserved Lysine in the E2 Protein.
Mutation
41 29630659 STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle.
Mutation
42 29643933 Human papillomavirus genome variants and head and neck cancers: a perspective.
Mutation
43 29893470 CIP2A facilitates the G1/S cell cycle transition via B-Myb in human papillomavirus 16 oncoprotein E6-expressing cells.
Mutation
44 30322153 HPV-18 E6 Oncoprotein and Its Spliced Isoform E6*I Regulate the Wnt/β-Catenin Cell Signaling Pathway through the TCF-4 Transcriptional Factor.
Mutation
45 30575267 Oncogenic comparison of human papillomavirus type 58 E7 variants.
Mutation
46 30676312 Oncogenicitiy Comparison of Human Papillomavirus Type 52 E6 Variants.
Mutation
47 30842331 Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication.
Mutation
48 30875834 The Protein Tyrosine Phosphatase H1 PTPH1 Supports Proliferation of Keratinocytes and is a Target of the Human Papillomavirus Type 8 E6 Oncogene.
Mutation
49 31426742 In silico prediction of structural changes in human papillomavirus type 16 (HPV16) E6 oncoprotein and its variants.
Mutation
50 31708575 Human papillomavirus as a driver of head and neck cancers.
Mutation
51 31915229 Human Papillomavirus 16 E6 and E7 Synergistically Repress Innate Immune Gene Transcription.
Mutation
52 31996427 Human Papillomavirus 58 E7 T20I/G63S Variant Isolated from an East Asian Population Possesses High Oncogenicity.
Mutation
53 32183180 Suppression of a Subset of Interferon-Induced Genes by Human Papillomavirus Type 16 E7 via a Cyclin Dependent Kinase 8-Dependent Mechanism.
Mutation
54 32304786 HPV16 L1 diversity and its potential impact on the vaccination-induced immunity.
Mutation
55 32350070 Phosphorylation of the Human Papillomavirus E2 Protein at Tyrosine 138 Regulates Episomal Replication.
Mutation
56 32435064 The possible regions to design Human Papilloma Viruses vaccine in Iranian L1 protein.
Mutation
57 32493825 Human Papillomavirus 31 Tyrosine 102 Regulates Interaction with E2 Binding Partners and Episomal Maintenance.
Mutation
58 32503989 Rational design of a multi-valent human papillomavirus vaccine by capsomere-hybrid co-assembly of virus-like particles.
Mutation
59 33155930 Human Papillomavirus E7 Oncoprotein Promotes Proliferation and Migration through the Transcription Factor E2F1 in Cervical Cancer Cells.
Mutation
60 33374731 High Risk α-HPV E6 Impairs Translesion Synthesis by Blocking POLη Induction.
Mutation
61 8627680 Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions.
Mutation
62 9223484 Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins.
Mutation
63 9733858 A fifteen-amino-acid peptide inhibits human papillomavirus E1-E2 interaction and human papillomavirus DNA replication in vitro.
Mutation
64 33573298 Modeling and Molecular Dynamics of the 3D Structure of the HPV16 E7 Protein and Its Variants.
Mutation
65 33636291 Worldwide genetic variations in high-risk human papillomaviruses capsid L1 gene and their impact on vaccine efficiency.
Mutation
Contents
Description
Group Note
  • Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
  • VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)