Overview of HPV associated Head and neck squamous cell carcinoma

Head and neck cancer is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands. Symptoms for head and neck cancer may include a lump or sore that does not heal, a sore throat that does not go away, trouble swallowing, or a change in the voice. In particular, HPV16 is a causal factor for some head and neck squamous-cell carcinomas (HNSCCs). Squamous cell cancers are common in areas of the mouth, including the inner lip, tongue, floor of mouth, gums, and hard palate. Cancers of the mouth are strongly associated with tobacco use, especially use of chewing tobacco or dipping tobacco, as well as heavy alcohol use. Cancers of this region, particularly the tongue, are more frequently treated with surgery than are other head and neck cancers.


ID Literature Title Group
1 28928286 HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers.
VIS-cistrome
2 25313082 Characterization of HPV and host genome interactions in primary head and neck cancers.
VIS-cistrome
3 25082736 Viral load, gene expression and mapping of viral integration sites in HPV16-associated HNSCC cell lines.
VIS-cistrome
4 32025001 The landscape of viral associations in human cancers.
VIS-cistrome
Contents
Description
Group Note
  • Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
  • VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)