Overview of HPV associated Head and neck carcinoma

Head and neck cancer is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands. Symptoms for head and neck cancer may include a lump or sore that does not heal, a sore throat that does not go away, trouble swallowing, or a change in the voice. About 90% of head and neck cancers are squamous cell cancers. Some head and neck cancers are caused by human papillomavirus (HPV). In particular, HPV16 is a causal factor for some head and neck squamous-cell carcinomas (HNSCCs). Approximately 15-25% of HNSCC contain genomic DNA from HPV.

ID	Literature	Title	Group
1	12050680	[Causal association between human papilloma virus infection and head and neck and esophageal squamous cell carcinoma].	Mutation
2	15006625	Human papillomavirus type 16 E6 and E7 genotypes in head-and-neck carcinomas.	Mutation
3	22558401	Human papillomavirus (HPV) 16 E6 variants in tonsillar cancer in comparison to those in cervical cancer in Stockholm, Sweden.	Mutation
4	30161236	Differences in the viral genome between HPV-positive cervical and oropharyngeal cancer.	Mutation

Contents
Description

Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)