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Overview of HTLV1 associated HTLV1 infection

The human T lymphotropic virus type 1(HTLV-1) is estimated to infect between 10 and 20 million people world wide. The virus causes at least two types of disease: a highly aggressive T cell malignancy, adult T cell leukaemia/lymphoma (ATL), and a variety of chronic inflammatory syndromes, most notably HTLV-1 associated myelopathy, which is also known as tropical spastic paraparesis (HAM/TSP). These syndromes are important causes of mortality and morbidity in the areas where HTLV-1 is endemic (PMID: 11002759).


ID Literature Title Group
1 29716616 Stability of the HTLV-1 glycoprotein 46 (gp46) gene in an endemic region of the Brazilian Amazon and the presence of a significant mutation (N93D) in symptomatic patients.
Mutation
2 25830656 The prevalence of human T-lymphotropic virus infection among blood donors in southeast China, 2004-2013.
Mutation
3 22166003 Correlation between LTR point mutations and proviral load levels among human T cell lymphotropic virus type 1 (HTLV-1) asymptomatic carriers.
Mutation
4 11027594 Antigenicity of chimeric synthetic peptides based on HTLV-1 antigens and the impact of epitope orientation.
Mutation
5 26516904 Low Proviral Load is Associated with Indeterminate Western Blot Patterns in Human T-Cell Lymphotropic Virus Type 1 Infected Individuals: Could Punctual Mutations be Related?
Mutation
6 33835501 Molecular characterization of HTLV-1 genomic region hbz from patients with different clinical conditions.
Mutation
7 33539355 Prevalence and evolutionary analyses of human T-cell lymphotropic virus in Guangdong province, China: Transcontinental and Japanese subtype lineages dominate the prevalence.
Mutation
Contents
Description
Group Note
  • Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
  • VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)