Overview of HPV associated Cervical lesion

Cervical lesion is also called an intraepithelial lesion, is an abnormality in the cells of your cervix that could eventually develop into cervical cancer. The persistent infection by specific types of high-risk human papillomaviruses (HR-HPVs) is essential for the progression of cervical lesions(PMID: 18199779). In the histological diagnosis cervical lesions were grouped as negative, CIN I, CIN II/III, and invasive carcinoma (IC).(PMID: 11328837)

ID	Literature	Title	Group
1	17429529	[Association between human papillomavirus (HPV) type 16 infection and E6/E7 gene variant and the cervical lesions in Beijing].	Mutation
2	27717385	L1 and L2 gene polymorphisms in HPV-58 and HPV-33: implications for vaccine design and diagnosis.	Mutation
3	29787003	HPV16 E6 mutations and p53 codon72 polymorphism among women with cervical intraepithelial neoplasia 2 and 3 in China.	Mutation
4	31138240	Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China.	Mutation
5	31511025	E6 and E7 gene polymorphisms in human papillomavirus Type-6 identified in Southwest China.	Mutation

Contents
Description

Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)