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Overview of HPV associated Cervical intraepithelial neoplasia

Cervical intraepithelial neoplasia also known as cervical dysplasia, is the abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer. More specifically, CIN refers to the potentially precancerous transformation of cells of the cervix.


ID Literature Title Group
1 26660085 Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer.
VIS-cistrome
2 27759101 Genome-wide profiling of the human papillomavirus DNA integration in cervical intraepithelial neoplasia and normal cervical epithelium by HPV capture technology.
VIS-cistrome
3 30567904 Comprehensive genomic variation profiling of cervical intraepithelial neoplasia and cervical cancer identifies potential targets for cervical cancer early warning.
VIS-cistrome
4 31102403 Risk stratification of cervical lesions using capture sequencing and machine learning method based on HPV and human integrated genomic profiles.
VIS-cistrome
5 10389753 Uniform distribution of HPV 16 E6 and E7 variants in patients with normal histology, cervical intra-epithelial neoplasia and cervical cancer.
Mutation
6 10475384 Rapid test for identification of a human papillomavirus 16 E6 L83V variant.
Mutation
7 11745467 Human papillomavirus 16 E6 polymorphisms in cervical lesions from different European populations and their correlation with human leukocyte antigen class II haplotypes.
Mutation
8 11870518 Variants of the long control region and the E6 oncogene in European human papillomavirus type 16 isolates: implications for cervical disease.
Mutation
9 12189229 Association of human papillomavirus type 58 variant with the risk of cervical cancer.
Mutation
10 12195358 Human papillomavirus type 16 intratypic variant infection and risk for cervical neoplasia in southern China.
Mutation
11 15491758 E2 sequence variations of HPV 16 among patients with cervical neoplasia seen in the Indian subcontinent.
Mutation
12 15665981 L1 sequence of a new human papillomavirus type-58 variant associated with cervical intraepithelial neoplasia.
Mutation
13 19256739 Distribution of HPV-16 intratypic variants among women with cervical intraepithelial neoplasia and invasive cervical cancer in Mongolia.
Mutation
14 19699050 Human papillomavirus type 16 E6 gene variations in Chinese population.
Mutation
15 20870281 Distribution of human papillomavirus 58 and 52 E6/E7 variants in cervical neoplasia in Chinese women.
Mutation
16 21051983 Distribution of human papillomavirus 16 E6/E7 variants in cervical cancer and intraepithelial neoplasia in Chinese women.
Mutation
17 21436703 Genetic diversity of HPV-16 E6, E7, and L1 genes in women with cervical lesions in Liaoning Province, China.
Mutation
18 22131113 Prevalence of HPV 16 genomic variant carrying a 63 bp duplicated sequence within the E1 gene in Slovenian women.
Mutation
19 22622951 Variant lineages of human papillomavirus type 18 in Northeast China populations characterized by sequence analysis of E6, E7, and L1 regions.
Mutation
20 22659102 Variations of human papillomavirus type 58 E6, E7, L1 genes and long control region in strains from women with cervical lesions in Liaoning province, China.
Mutation
21 22684534 Molecular and phylogenetic analysis of the HPV 16 E4 gene in cervical lesions from women in Greece.
Mutation
22 23015309 Human papillomavirus type 52 polymorphism and high-grade lesions of the uterine cervix.
Mutation
23 23203106 Genomic polymorphism of human papillomavirus type 52 in women from Northeast China.
Mutation
24 23881083 Nucleotide polymorphisms of the human papillomavirus 16 E1 gene.
Mutation
25 23946477 Molecular and evolutionary analysis of HPV16 E6 and E7 genes in Greek women.
Mutation
26 24099556 Genetic variations of E6 and long control region of human papillomavirus type 16 from patients with cervical lesion in Liaoning, China.
Mutation
27 25143263 Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients.
Mutation
28 26192265 Distribution of human papilloma virus type 16 E6/E7 gene mutation in cervical precancer or cancer: A case control study in Guizhou Province, China.
Mutation
29 27038009 Association between human papillomavirus type 16 E6 and E7 variants with subsequent persistent infection and recurrence of cervical high-grade squamous intraepithelial lesion after conization.
Mutation
30 27977741 Analysis of Sequence Variation and Risk Association of Human Papillomavirus 52 Variants Circulating in Korea.
Mutation
31 28270859 Genetic variability in E6, E7 and L1 genes of Human Papillomavirus 62 and its prevalence in Mexico.
Mutation
32 28325903 Whole-Genome Analysis of Human Papillomavirus Types 16, 18, and 58 Isolated from Cervical Precancer and Cancer Samples in Chinese Women.
Mutation
33 29981762 Genetic variability and lineage phylogeny of human papillomavirus type 45 based on E6 and E7 genes in Southwest China.
Mutation
34 30471332 Genetic variability and oncogenic risk association of human papillomavirus type 58 E6 and E7 genes in Taizhou area, China.
Mutation
35 30930693 Genetic variations in E6, E7 and the long control region of human papillomavirus type 16 among patients with cervical lesions in Xinjiang, China.
Mutation
36 30995759 Whole-Genome Analysis of Human Papillomavirus Type 16 Prevalent in Japanese Women with or without Cervical Lesions.
Mutation
37 31552532 Mutational landscape and intra-host diversity of human papillomavirus type 16 long control region and E6 variants in cervical samples.
Mutation
38 31670402 Genetic variability and functional implication of HPV16 from cervical intraepithelial neoplasia in Shanghai women.
Mutation
39 31727676 A Phase II, Prospective, Randomized, Multicenter, Open-Label Study of GX-188E, an HPV DNA Vaccine, in Patients with Cervical Intraepithelial Neoplasia 3.
Mutation
40 31832087 Phylogeny and polymorphism in the E6 and E7 of human papillomavirus: alpha-9 (HPV16, 31, 33, 52, 58), alpha-5 (HPV51), alpha-6 (HPV53, 66), alpha-7 (HPV18, 39, 59, 68) and alpha-10 (HPV6, 44) in women from Shanghai.
Mutation
41 31944308 Characterization of major capsid protein (L1) variants of Human papillomavirus type 16 by cervical neoplastic status in Indian women: Phylogenetic and functional analysis.
Mutation
42 9485042 Human papillomavirus 16 E6 variants are more prevalent in invasive cervical carcinoma than the prototype.
Mutation
Contents
Description
Group Note
  • Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
  • VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)