Overview of HPV associated Buschke-Lowenstein Tumor

Giant condyloma acuminatum (also known as a Buschke–Löwenstein tumor ) is a rare cutaneous condition characterized by an aggressive, wart-like growth that is a verrucous carcinoma. It is attributed to human papillomavirus. Due to their size, these tumors can be locally invasive and destructive. Owing to their impressive growth patterns, Buschke-Löwenstein tumors displace and destroy adjacent structures from compression. In general these masses are benign, but the potential for malignant transformation to squamous cell carcinoma exists in the long term, as does the rare risk for metastasis.Buschke-Löwensteoin tumors are frequently associated with HPV subtypes 6 and 11.


ID Literature Title Group
1 19508521 Extensive anal condylomatosis: prognosis in relation to viral and host factors.
Mutation
Contents
Description
Group Note
  • Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
  • VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)