Overview of HBV associated Acute exacerbation of chronic hepatitis B

Acute exacerbation of hepatitis occurs in individuals chronically infected with HBV. They have been infected perinatally or in an early infancy and are tolerant to HBV. Later in their lives, however, the tolerance to HBV is terminated, and immune responses are elicited in them. As a result, severe hepatitis can develop along with subjective symptoms and abnormalities in liver function tests (PMID: 18410611).

ID	Literature	Title	Group
1	18410611	Detection of HBV core promoter and precore mutations helps distinguish flares of chronic hepatitis from acute hepatitis B.	Mutation
2	20080060	Features and clinical implications of hepatitis B virus genotypes and mutations in basal core promoter/precore region in 507 Chinese patients with acute and chronic hepatitis B.	Mutation
3	22930503	Clinical characteristics and chronicity of acute hepatitis B induced by lamivudine-resistant strains.	Mutation
4	25822666	Hepatitis B virus genotype distribution and genotype-specific BCP/preCore substitutions in acute and chronic infections in Argentina.	Mutation
5	28822954	The variability of hepatitis B envelope is associated with HBs antigen persistence in either chronic or acute HBV genotype A infection.	Mutation

Contents
Description

Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)