Colon Cancer: Gene >> TOP1

Mutation ID	1
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41123245:41123245(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs56111014
CDS Mutation	c.2246G>A
AA Mutation	p.Arg749Gln(p.R749Q)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41076226:41076226(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.211G>T
AA Mutation	p.Asp71Tyr(p.D71Y)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41076281:41076281(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs778237366
CDS Mutation	c.266G>A
AA Mutation	p.Arg89Gln(p.R89Q)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	4
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41101259:41101259(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1214G>A
AA Mutation	p.Arg405Gln(p.R405Q)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	5
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41084502:41084502(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.548A>C
AA Mutation	p.Lys183Thr(p.K183T)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	6
Mutation Consequence	missense_variant;splice_region_variant
Transcription ID	ENST00000361337
Start	41118169:41118169(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1823C>T
AA Mutation	p.Pro608Leu(p.P608L)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	7
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000361337
Start	41061426:41061426(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.91C>A
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	8
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000361337
Start	41077585:41077585(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.283C>A
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	9
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000361337
Start	41101317:41101317(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1272T>C
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	10
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000361337
Start	41092541:41092541(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.684C>A
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	11
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000361337
Start	41100075:41100075(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	null
CDS Mutation	c.999delA
AA Mutation	p.Lys333AsnfsTer3(p.K333Nfs*3)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	12
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000361337
Start	41118257:41118257(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	null
CDS Mutation	c.1915delA
AA Mutation	p.Thr639LeufsTer6(p.T639Lfs*6)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	13
Mutation Consequence	stop_gained
Transcription ID	ENST00000361337
Start	41080167:41080167(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.418C>T
AA Mutation	p.Arg140Ter(p.R140*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Mutation ID	14
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000361337
Start	41112823:41112824(version: GRCh38)
Mutation Type	INS
dbSNP_RS	novel
CDS Mutation	c.1356dupA
AA Mutation	p.Cys453MetfsTer40(p.C453Mfs*40)
Mutation Classification	Frame_Shift_Ins
Feature Type	Transcript

Rectum Cancer: Gene >> TOP1

Mutation ID	1
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41084481:41084481(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.527C>A
AA Mutation	p.Pro176His(p.P176H)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41081186:41081186(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.453A>C
AA Mutation	p.Lys151Asn(p.K151N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	missense_variant;splice_region_variant
Transcription ID	ENST00000361337
Start	41116278:41116278(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1708A>C
AA Mutation	p.Thr570Pro(p.T570P)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	4
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41084485:41084485(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.531G>T
AA Mutation	p.Lys177Asn(p.K177N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	5
Mutation Consequence	missense_variant;splice_region_variant
Transcription ID	ENST00000361337
Start	41112925:41112925(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1452G>T
AA Mutation	p.Lys484Asn(p.K484N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	6
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41081216:41081216(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.483G>T
AA Mutation	p.Lys161Asn(p.K161N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	7
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41097233:41097233(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.744G>T
AA Mutation	p.Lys248Asn(p.K248N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	8
Mutation Consequence	missense_variant
Transcription ID	ENST00000361337
Start	41114039:41114039(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1522C>T
AA Mutation	p.Arg508Cys(p.R508C)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	9
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000361337
Start	41084473:41084474(version: GRCh38)
Mutation Type	INS
dbSNP_RS	novel
CDS Mutation	c.525dupA
AA Mutation	p.Pro176ThrfsTer4(p.P176Tfs*4)
Mutation Classification	Frame_Shift_Ins
Feature Type	Transcript