Colon Cancer: Gene >> MLH3

Mutation ID	1
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75048621:75048621(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1035A>C
AA Mutation	p.Lys345Asn(p.K345N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75041626:75041626(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs569011240
CDS Mutation	c.3454C>T
AA Mutation	p.Arg1152Cys(p.R1152C)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75047191:75047191(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.2465G>A
AA Mutation	p.Ser822Asn(p.S822N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	4
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75047290:75047290(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.2366A>G
AA Mutation	p.Asp789Gly(p.D789G)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	5
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75048781:75048781(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.875C>T
AA Mutation	p.Ser292Leu(p.S292L)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	6
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75049289:75049289(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.367C>A
AA Mutation	p.Leu123Met(p.L123M)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	7
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75017168:75017168(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs753388082
CDS Mutation	c.4276G>A
AA Mutation	p.Ala1426Thr(p.A1426T)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	8
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75049549:75049549(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.107C>A
AA Mutation	p.Ala36Asp(p.A36D)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	9
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75048298:75048298(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1358T>C
AA Mutation	p.Met453Thr(p.M453T)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	10
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75030607:75030607(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.3923T>C
AA Mutation	p.Phe1308Ser(p.F1308S)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	11
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75046726:75046726(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2930C>A
AA Mutation	p.Ser977Tyr(p.S977Y)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	12
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75046732:75046732(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2924A>C
AA Mutation	p.Asn975Thr(p.N975T)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	13
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75048554:75048554(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1102G>T
AA Mutation	p.Asp368Tyr(p.D368Y)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	14
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75039943:75039943(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.3538C>G
AA Mutation	p.Arg1180Gly(p.R1180G)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	15
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75047877:75047877(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1779A>C
AA Mutation	p.Arg593Ser(p.R593S)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	16
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75047857:75047857(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs28756984
CDS Mutation	c.1799G>A
AA Mutation	p.Arg600Gln(p.R600Q)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	17
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000355774
Start	75018952:75018952(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.4119C>T
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	18
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000355774
Start	75017133:75017133(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.4311T>C
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	19
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000355774
Start	75048972:75048972(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	null
CDS Mutation	c.684delT
AA Mutation	p.Phe228LeufsTer27(p.F228Lfs*27)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	20
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000355774
Start	75049120:75049121(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	null
CDS Mutation	c.535_536delTC
AA Mutation	p.Ser179ThrfsTer13(p.S179Tfs*13)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	21
Mutation Consequence	stop_gained
Transcription ID	ENST00000355774
Start	75047900:75047900(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1756G>T
AA Mutation	p.Glu586Ter(p.E586*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Mutation ID	22
Mutation Consequence	stop_gained
Transcription ID	ENST00000355774
Start	75047663:75047663(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1993G>T
AA Mutation	p.Glu665Ter(p.E665*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Mutation ID	23
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000355774
Start	75047878:75047879(version: GRCh38)
Mutation Type	INS
dbSNP_RS	novel
CDS Mutation	c.1777_1778insCTTATATTCGTTCT
AA Mutation	p.Arg593ThrfsTer22(p.R593Tfs*22)
Mutation Classification	Frame_Shift_Ins
Feature Type	Transcript

Mutation ID	24
Mutation Consequence	splice_donor_variant
Transcription ID	ENST00000355774
Start	75046375:75046375(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.3280+1G>T
Mutation Classification	Splice_Site
Feature Type	Transcript

Rectum Cancer: Gene >> MLH3

Mutation ID	1
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75048604:75048604(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1052A>C
AA Mutation	p.Glu351Ala(p.E351A)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75049442:75049442(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs370545907
CDS Mutation	c.214C>T
AA Mutation	p.Arg72Cys(p.R72C)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75048458:75048458(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1198T>G
AA Mutation	p.Ser400Ala(p.S400A)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	4
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75030581:75030581(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.3949C>T
AA Mutation	p.Arg1317Trp(p.R1317W)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	5
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75046387:75046387(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.3269T>C
AA Mutation	p.Val1090Ala(p.V1090A)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	6
Mutation Consequence	missense_variant
Transcription ID	ENST00000355774
Start	75048083:75048083(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1573C>A
AA Mutation	p.Leu525Ile(p.L525I)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	7
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000355774
Start	75047635:75047635(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	null
CDS Mutation	c.2021delA
AA Mutation	p.Asn674IlefsTer6(p.N674Ifs*6)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	8
Mutation Consequence	stop_gained
Transcription ID	ENST00000355774
Start	75048983:75048983(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.673G>T
AA Mutation	p.Glu225Ter(p.E225*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Mutation ID	9
Mutation Consequence	stop_gained
Transcription ID	ENST00000355774
Start	75047345:75047345(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2311G>T
AA Mutation	p.Glu771Ter(p.E771*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Mutation ID	10
Mutation Consequence	splice_acceptor_variant
Transcription ID	ENST00000355774
Start	75032180:75032180(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.3716-1G>T
Mutation Classification	Splice_Site
Feature Type	Transcript