Primary Site >> Colorectal Cancer

Gene >> MLH3

  • 2000
  • 2001
  • 2002
  • 2003
  • 2004
  • 2005
  • 2006
  • 2007
  • 2008
  • 2009
  • 2010
  • 2011
  • 2013
  • 2014
  • 2015
  • 2016
  • 2017
  • 2018
Ref: MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability.
PMID: 10615123
Ref: Germline and somatic mutation analysis of MLH3 in MSI-positive colorectal cancer.
PMID: 10934138
Ref: High throughput genetic screening for the detection of hereditary non-polyposis colon cancer (HNPCC) using capillary electrophoresis.
PMID: 11121520
 Ref: Germline and somatic mutation analyses in the DNA mismatch repair gene MLH3: Evidence for somatic mutation in colorectal cancers.
PMID: 11317354
 Ref: Endometrial and colorectal tumors from patients with hereditary nonpolyposis colon cancer display different patterns of microsatellite instability.
PMID: 12057899
 Ref: Two mismatch repair gene mutations found in a colon cancer patient--which one is pathogenic?
PMID: 12522549
Ref: Little evidence for involvement of MLH3 in colorectal cancer predisposition.
PMID: 12800209
 Ref: No association between two MLH3 variants (S845G and P844L)and colorectal cancer risk.
PMID: 15193445
 Ref: Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse.
PMID: 16204034
Ref: Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair.
PMID: 16322221
 Ref: MLH3 mutation in endometrial cancer.
PMID: 16885347
 Ref: Genomic rearrangements in MSH2, MLH1 or MSH6 are rare in HNPCC patients carrying point mutations.
PMID: 16837128
 Ref: Common variants in mismatch repair genes and risk of colorectal cancer.
PMID: 18364438
Ref: The first functional study of MLH3 mutations found in cancer patients.
PMID: 18521850
Ref: Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.
PMID: 18551179
 Ref: Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer.
PMID: 19115210
Ref: Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome.
PMID: 19156873
Ref: Mismatch repair genes in Lynch syndrome: a review.
PMID: 19466295
Ref: Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73.
PMID: 19558638
 Ref: Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation.
PMID: 19949877
Ref: MMR gene expression pattern in sporadic colorectal cancer.
PMID: 20593048
 Ref: Association of low-risk MSH3 and MSH2 variant alleles with Lynch syndrome: probability of synergistic effects.
PMID: 21128252
Ref: Alterations of copy number of methylation pattern in mismatch repair genes by methylation specific-multiplex ligation-dependent probe amplification in cases of colon cancer.
PMID: 24052709
 Ref: Evaluation of tumor suppressor gene expressions and aberrant methylation in the colon of cancer-induced rats: a pilot study.
PMID: 24065530
 Ref: Mismatch repair deficiency in ovarian cancer -- molecular characteristics and clinical implications.
PMID: 24333356
Ref: Variations in mismatch repair genes and colorectal cancer risk and clinical outcome.
PMID: 24755277
 Ref: Comprehensive screening for mutations associated with colorectal cancer in unselected cases reveals penetrant and nonpenetrant mutations.
PMID: 25142776
Ref: Advances in the study of Lynch syndrome in China.
PMID: 26078562
Ref: Segregation of a novel MLH1 mutation in an Iranian Lynch syndrome family.
PMID: 26149658
 Ref: Coexistence of MLH3 germline variants in colon cancer patients belonging to families with Lynch syndrome-associated brain tumors.
PMID: 27401157
 Ref: Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair.
PMID: 29069730
 Ref: The polymorphisms of miRNA-binding site in MLH3 and ERCC1 were linked to the risk of colorectal cancer in a case-control study.
PMID: 29516665
Ref: Novel MSH2 splice-site mutation in a young patient with Lynch syndrome.
PMID: 29568967
Ref: Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls - a preliminary report.
PMID: 29876008
Ref: [Genetic variations in MLH3 and MSH2 genes are associated with the sensitivity and prognosis in locally advanced rectal cancer patients receiving preoperative chemoradiotherapy].
PMID: 29936769