Mutation

Primary Site >> Colorectal Cancer

Colon Cancer: Gene >> LGR4

Mutation ID	1
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27392502:27392502(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs376236224
CDS Mutation	c.274G>A
AA Mutation	p.Asp92Asn(p.D92N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27367949:27367949(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.2774C>T
AA Mutation	p.Ala925Val(p.A925V)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	missense_variant;splice_region_variant
Transcription ID	ENST00000379214
Start	27376368:27376368(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1112C>T
AA Mutation	p.Ser371Phe(p.S371F)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	4
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27382231:27382231(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.715G>A
AA Mutation	p.Glu239Lys(p.E239K)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	5
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27368981:27368981(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1742C>A
AA Mutation	p.Ser581Tyr(p.S581Y)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	6
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27368273:27368273(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs147618701
CDS Mutation	c.2450G>A
AA Mutation	p.Arg817Gln(p.R817Q)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	7
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27372364:27372364(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1414G>A
AA Mutation	p.Ala472Thr(p.A472T)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	8
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27368964:27368964(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1759A>G
AA Mutation	p.Met587Val(p.M587V)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	9
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27368907:27368907(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1816G>A
AA Mutation	p.Ala606Thr(p.A606T)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	10
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27385278:27385278(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.592A>G
AA Mutation	p.Thr198Ala(p.T198A)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	11
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27385385:27385385(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.485A>G
AA Mutation	p.Asp162Gly(p.D162G)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	12
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27385434:27385434(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs769421305
CDS Mutation	c.436G>A
AA Mutation	p.Glu146Lys(p.E146K)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	13
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27368996:27368996(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1727T>G
AA Mutation	p.Phe576Cys(p.F576C)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	14
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27376359:27376359(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs371443871
CDS Mutation	c.1121G>A
AA Mutation	p.Arg374His(p.R374H)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	15
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27368385:27368385(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs775198460
CDS Mutation	c.2338G>A
AA Mutation	p.Glu780Lys(p.E780K)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	16
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27368568:27368568(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2155T>G
AA Mutation	p.Leu719Val(p.L719V)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	17
Mutation Consequence	missense_variant;splice_region_variant
Transcription ID	ENST00000379214
Start	27376368:27376368(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1112C>A
AA Mutation	p.Ser371Tyr(p.S371Y)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	18
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27368723:27368723(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.2000T>G
AA Mutation	p.Leu667Arg(p.L667R)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	19
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000379214
Start	27378705:27378705(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1035T>C
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	20
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000379214
Start	27368149:27368149(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2574C>T
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	21
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000379214
Start	27368386:27368386(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2337C>T
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	22
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000379214
Start	27368353:27368353(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2370T>C
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	23
Mutation Consequence	stop_gained
Transcription ID	ENST00000379214
Start	27367941:27367941(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2782C>T
AA Mutation	p.Arg928Ter(p.R928*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Mutation ID	24
Mutation Consequence	protein_altering_variant
Transcription ID	ENST00000379214
Start	27369035:27369036(version: GRCh38)
Mutation Type	INS
dbSNP_RS	novel
CDS Mutation	c.1687_1688insAGC
AA Mutation	p.Thr563delinsLysPro(p.T563delinsKP)
Mutation Classification	In_Frame_Ins
Feature Type	Transcript

Rectum Cancer: Gene >> LGR4

Mutation ID	1
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27368688:27368688(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2035T>G
AA Mutation	p.Phe679Val(p.F679V)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27368960:27368960(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1763G>A
AA Mutation	p.Gly588Glu(p.G588E)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	missense_variant
Transcription ID	ENST00000379214
Start	27373988:27373988(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1240C>T
AA Mutation	p.Pro414Ser(p.P414S)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	4
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000379214
Start	27368727:27368727(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	null
CDS Mutation	c.1996delG
AA Mutation	p.Ala666ProfsTer6(p.A666Pfs*6)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript