Primary Site >> Colorectal Cancer

Gene >> LGR4

Journal: Cancer Res. 2006 Dec 15;66(24):11623-31.
Title: Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis.
Author: Gao, Yun|Kitagawa, Kyoko|Hiramatsu, Yoshihiro|Kikuchi, Hirotoshi|Isobe, Tomoyasu|Shimada, Mai|Uchida, Chiharu|Hattori, Takayuki|Oda, Toshiaki|Nakayama, Keiko|Nakayama, Keiichi I|Tanaka, Tatsuo|Konno, Hiroyuki|Kitagawa, Masatoshi
PMID: 17178856
Journal: PLoS One. 2012;7(5):e37137.
Title: LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor.
Author: Gong, Xing|Carmon, Kendra S|Lin, Qiushi|Thomas, Anthony|Yi, Jing|Liu, Qingyun
PMID: 22615920
Journal: Carcinogenesis. 2013 Dec;34(12):2861-9.
Title: GPR48, a poor prognostic factor, promotes tumor metastasis and activates beta-catenin/TCF signaling in colorectal cancer.
Author: Wu, Jinhua|Xie, Na|Xie, Ke|Zeng, Jun|Cheng, Lin|Lei, Yunlong|Liu, Yuan|Song, Linhong|Dong, Dandan|Chen, Yi|Zeng, Rui|Nice, Edouard C|Huang, Canhua|Wei, Yuquan
PMID: 23803691
Journal: PLoS One. 2013 Oct 21;8(10):e78144.
Title: Analysis of LGR4 receptor distribution in human and mouse tissues.
Author: Yi, Jing|Xiong, Wei|Gong, Xing|Bellister, Seth|Ellis, Lee M|Liu, Qingyun
PMID: 24205130
Journal: Genes Dev. 2014 Feb 15;28(4):305-16.
Title: The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength.
Author: de Lau, Wim|Peng, Weng Chuan|Gros, Piet|Clevers, Hans
PMID: 24532711
Journal: Oncogene. 2015 Sep 3;34(36):4692-701.
Title: Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.
Author: Gong, X|Yi, J|Carmon, K S|Crumbley, C A|Xiong, W|Thomas, A|Fan, X|Guo, S|An, Z|Chang, J T|Liu, Q J
PMID: 25531322
Journal: Front Endocrinol (Lausanne). 2015 Aug 25;6:131.
Title: LGR4 and Its Role in Intestinal Protection and Energy Metabolism.
Author: Li, Ziru|Zhang, Weizhen|Mulholland, Michael W
PMID: 26379625
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Nov;18(11):1179-81.
Title: [Research progress of Lgr4 in gastrointestinal carcinomas].
Author: Xiao, Yibin|Chen, Lin
PMID: 26616818
Journal: Genet Mol Res. 2016 Mar 4;15(1):15017326.
Title: 5-Fluorouracil induces apoptosis of colorectal cancer cells.
Author: Zhang, J T|Zhou, W L|He, C|Liu, T|Li, C Y|Wang, L
PMID: 26985934
Journal: Gut. 2017 Jun;66(6):1095-1105.
Title: RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
Author: Hilkens, John|Timmer, Nikki C|Boer, Mandy|Ikink, Gerjon J|Schewe, Matthias|Sacchetti, Andrea|Koppens, Martijn A J|Song, Ji-Ying|Bakker, Elvira R M
PMID: 27511199
Journal: Nat Cell Biol. 2018 Oct;20(10):1134-1144.
Title: LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.
Author: Zhu, Pingping|Wu, Jiayi|Wang, Yanying|Zhu, Xiaoxiao|Lu, Tiankun|Liu, Benyu|He, Luyun|Ye, Buqing|Wang, Shuo|Meng, Shu|Fan, Dongdong|Wang, Jing|Yang, Liuliu|Qin, Xiwen|Du, Ying|Li, Chong|He, Lei|Ren, Weizheng|Wu, Xin|Tian, Yong|Fan, Zusen
PMID: 30224759