Primary Site >> Colorectal Cancer

Gene >> LGR4

  • 2006
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  • 2017
  • 2018
Ref: Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis.
PMID: 17178856
Ref: LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor.
PMID: 22615920
Ref: GPR48, a poor prognostic factor, promotes tumor metastasis and activates beta-catenin/TCF signaling in colorectal cancer.
PMID: 23803691
Ref: Analysis of LGR4 receptor distribution in human and mouse tissues.
PMID: 24205130
Ref: The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength.
PMID: 24532711
Ref: Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.
PMID: 25531322
Ref: LGR4 and Its Role in Intestinal Protection and Energy Metabolism.
PMID: 26379625
Ref: [Research progress of Lgr4 in gastrointestinal carcinomas].
PMID: 26616818
Ref: 5-Fluorouracil induces apoptosis of colorectal cancer cells.
PMID: 26985934
Ref: RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
PMID: 27511199
Ref: LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.
PMID: 30224759