Primary Site >> Colorectal Cancer

Gene >> PDGFRA

Journal: Am J Med Genet A. 2003 Nov 1;122A(4):303-14.
Title: Molecular dimensions of gastrointestinal tumors: some thoughts for digestion.
Author: Cohen, M Michael Jr
PMID: 14518068
Journal: J Med Chem. 2005 Mar 10;48(5):1359-66.
Title: Novel potent orally active selective VEGFR-2 tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas.
Author: Kubo, Kazuo|Shimizu, Toshiyuki|Ohyama, Shin-ichi|Murooka, Hideko|Iwai, Akemi|Nakamura, Kazuhide|Hasegawa, Kazumasa|Kobayashi, Yoshiko|Takahashi, Noriko|Takahashi, Kazumi|Kato, Shinichiro|Izawa, Toshio|Isoe, Toshiyuki
PMID: 15743179
Journal: Oncogene. 2007 Mar 29;26(14):2133-5. Epub 2006 Oct 2.
Title: Absence of tyrosine kinase mutations in Japanese colorectal cancer patients.
Author: Shao, R-X|Kato, N|Lin, L-J|Muroyama, R|Moriyama, M|Ikenoue, T|Watabe, H|Otsuka, M|Guleng, B|Ohta, M|Tanaka, Y|Kondo, S|Dharel, N|Chang, J-H|Yoshida, H|Kawabe, T|Omata, M
PMID: 17016444
Journal: World J Gastroenterol. 2007 Mar 21;13(11):1659-65.
Title: Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas.
Author: Bian, Yue-Hong|Huang, Shu-Hong|Yang, Ling|Ma, Xiao-Li|Xie, Jing-Wu|Zhang, Hong-Wei
PMID: 17461467
Journal: Genome Biol. 2007;8(7):R131.
Title: Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer.
Author: Kaiser, Sergio|Park, Young-Kyu|Franklin, Jeffrey L|Halberg, Richard B|Yu, Ming|Jessen, Walter J|Freudenberg, Johannes|Chen, Xiaodi|Haigis, Kevin|Jegga, Anil G|Kong, Sue|Sakthivel, Bhuvaneswari|Xu, Huan|Reichling, Timothy|Azhar, Mohammad|Boivin, Gregory P|
PMID: 17615082
Journal: Cancer Sci. 2008 Feb;99(2):253-9.
Title: Aberrant methylation status of known methylation-sensitive CpG islands in gastrointestinal stromal tumors without any correlation to the state of c-kit and PDGFRA gene mutations and their malignancy.
Author: Saito, Kana|Sakurai, Shinji|Sano, Takaaki|Sakamoto, Kazuha|Asao, Takayuki|Hosoya, Yoshinori|Nakajima, Takashi|Kuwano, Hiroyuki
PMID: 18271923
Journal: Oncol Rep. 2008 Mar;19(3):697-704.
Title: PDGFRalpha/beta expression correlates with the metastatic behavior of human colorectal cancer: a possible rationale for a molecular targeting strategy.
Author: Wehler, Thomas C|Frerichs, Kirsten|Graf, Claudine|Drescher, Daniel|Schimanski, Katrin|Biesterfeld, Stefan|Berger, Martin R|Kanzler, Stephan|Junginger, Theodor|Galle, Peter R|Moehler, Markus|Gockel, Ines|Schimanski, Carl C
PMID: 18288404
Journal: Ai Zheng. 2008 Jun;27(6):654-60.
Title: [Expression and clinical significance of PDGFRalpha and PDGFRbeta in colorectal cancer].
Author: Zhu, Hao-Tu|Han, Jun|Ma, Lin
PMID: 18570744
Journal: Tumori. 2009 Mar-Apr;95(2):240-2.
Title: Association of gastrointestinal stromal tumor and acute myeloid leukemia preceded by myelodysplastic syndrome with refractory anemia.
Author: Sonmez, Mehmet|Arslan, Mehmet|Cobanoglu, Umit|Kavgaci, Halil|Ozbas, Hasan Mucahit|Aydin, Fazil|Ovali, Ercument|Omay, Serdar Bedii
PMID: 19579873
Journal: Int J Clin Exp Pathol. 2009 Nov 25;3(2):162-8.
Title: Gastrointestinal stromal tumor of the digestive organs: a histopathologic study of 31 cases in a single Japanese institute.
Author: Terada, Tadashi
PMID: 20126584
Journal: Interact Cardiovasc Thorac Surg. 2010 Feb;10(2):228-31.
Title: Tyrosine kinase expression in pulmonary metastases and paired primary tumors.
Author: Muehling, Bernd M|Toelkes, Sara|Schelzig, Hubert|Barth, Thomas F E|Sunder-Plassmann, Ludger
PMID: 19948538
Journal: Int J Colorectal Dis. 2010 Feb;25(2):181-6.
Title: K-ras mutation status correlates with the expression of VEGFR1, VEGFR2, and PDGFRalpha in colorectal cancer.
Author: Schimanski, Carl C|Zimmermann, Tim|Schmidtmann, Irene|Gockel, Ines|Lang, Hauke|Galle, Peter R|Moehler, Markus|Berger, Martin R
PMID: 19936766
Journal: Genes Chromosomes Cancer. 2010 Feb;49(2):91-8.
Title: Hereditary gastrointestinal stromal tumors sharing the KIT Exon 17 germline mutation p.Asp820Tyr develop through different cytogenetic progression pathways.
Author: Veiga, Isabel|Silva, Mara|Vieira, Joana|Pinto, Carla|Pinheiro, Manuela|Torres, Lurdes|Soares, Marta|Santos, Lucio|Duarte, Hugo|Bastos, Artur L|Coutinho, Camila|Dinis, Jose|Lopes, Carlos|Teixeira, Manuel R
PMID: 19847891
Journal: Cancer Res. 2011 Feb 1;71(3):1092-102.
Title: Hedgehog signaling drives cellular survival in human colon carcinoma cells.
Author: Mazumdar, Tapati|DeVecchio, Jennifer|Shi, Ting|Jones, Janay|Agyeman, Akwasi|Houghton, Janet A
PMID: 21135115
Journal: World J Gastroenterol. 2012 Feb 14;18(6):570-5.
Title: Identification of differential gene expressions in colorectal cancer and polyp by cDNA microarray.
Author: Dai, Yi-Chen|Zhu, Xiao-San|Nan, Qing-Zhen|Chen, Zhang-Xin|Xie, Jun-Pei|Fu, Yu-Ka|Lin, Yuan-Yuan|Lian, Qing-Na|Sang, Qiao-Fang|Zhan, Xiao-Juan
PMID: 22363125
Journal: BMC Cancer. 2012 Nov 12;12:514.
Title: PDGFRalpha/beta and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome.
Author: Estevez-Garcia, Purificacion|Castano, Angel|Martin, Ana C|Lopez-Rios, Fernando|Iglesias, Joaquin|Munoz-Galvan, Sandra|Lopez-Calderero, Iker|Molina-Pinelo, Sonia|Pastor, Maria D|Carnero, Amancio|Paz-Ares, Luis|Garcia-Carbonero, Rocio
PMID: 23146028
Journal: Int J Clin Exp Pathol. 2013;6(3):385-94. Epub 2013 Feb 15.
Title: Histopathologic study of the rectum in 1,464 consecutive rectal specimens in a single Japanese hospital: II. malignant lesions.
Author: Terada, Tadashi
PMID: 23412998
Journal: PLoS Genet. 2013 Apr;9(4):e1003464.
Title: Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.
Author: Giacomini, Craig P|Sun, Steven|Varma, Sushama|Shain, A Hunter|Giacomini, Marilyn M|Balagtas, Jay|Sweeney, Robert T|Lai, Everett|Del Vecchio, Catherine A|Forster, Andrew D|Clarke, Nicole|Montgomery, Kelli D|Zhu, Shirley|Wong, Albert J|van de Rijn, Matt|Wes
PMID: 23637631
Journal: Kaohsiung J Med Sci. 2013 Aug;29(8):460-3.
Title: Inflammatory fibroid polyp of rectum mimicking rectal cancer.
Author: Jin, Jong-Shiaw|Wu, Chiao-Sen|Yeh, Chih-Haw|Huang, Bee-Piao|Tsao, Tang-Yi
PMID: 23906237
Journal: Tumour Biol. 2014 May;35(5):4357-62.
Title: Clinicopathologic factors predicting outcomes in patients with gastrointestinal stromal tumors of the rectum and colon.
Author: Zhou, Zhongguo|Chen, Zhanpeng|Chen, Minshan|Wang, Ruojing|Yin, Ying|Yao, Yuan
PMID: 24375257
Journal: Ann Surg Oncol. 2014 Aug;21(8):2642-9.
Title: The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study.
Author: Abdul-Jalil, Khairun I|Sheehan, Katherine M|Toomey, Sinead|Schmid, Jasmin|Prehn, Jochen|O'Grady, Anthony|Cummins, Robert|O'Neill, Brian|McNamara, Deborah A|Deasy, Joseph|Breathnach, Oscar|Grogan, Liam|Rogers, Ailin|Doherty, Glen|Winter, Des|Ryan, John|El-
PMID: 24700299
Journal: Am J Physiol Gastrointest Liver Physiol. 2014 Oct 1;307(7):G749-59.
Title: PDGF receptor-alpha promotes TGF-beta signaling in hepatic stellate cells via transcriptional and posttranscriptional regulation of TGF-beta receptors.
Author: Liu, Chunsheng|Li, Jiachu|Xiang, Xiaoyu|Guo, Luyang|Tu, Kangsheng|Liu, Qinghua|Shah, Vijay H|Kang, Ningling
PMID: 25169976
Journal: Mol Med Rep. 2015 Nov;12(5):7072-8.
Title: MiR-34a inhibits colon cancer proliferation and metastasis by inhibiting platelet-derived growth factor receptor alpha.
Author: Li, Chunyan|Wang, Yulin|Lu, Shuming|Zhang, Zhuqing|Meng, Hua|Liang, Lina|Zhang, Yan|Song, Bo
PMID: 26324236
Journal: PLoS One. 2015 Nov 23;10(11):e0142612.
Title: Regorafenib: Antitumor Activity upon Mono and Combination Therapy in Preclinical Pediatric Malignancy Models.
Author: Daudigeos-Dubus, Estelle|Le Dret, Ludivine|Lanvers-Kaminsky, Claudia|Bawa, Olivia|Opolon, Paule|Vievard, Albane|Villa, Irene|Pages, Melanie|Bosq, Jacques|Vassal, Gilles|Zopf, Dieter|Geoerger, Birgit
PMID: 26599335
Journal: J BUON. 2015 Sep-Oct;20(5):1193-200.
Title: Is there a correlation between peripheral blood expression of angiogenic transcriptional factors/receptors and colorectal cancer?
Author: Manzat-Saplacan, Roberta M|Balacescu, Loredana|Gherman, Claudia|Visan, Simona|Chira, Romeo I|Bintintan, Adriana|Nagy, Georgiana|Popovici, Cornelia|Valean, Simona D|Anca, Craiu|Bintintan, Vasile|Scurtu, Razvan|Mircea, Petru A|Berindan-Neagoe, Ioana|Ciulean
PMID: 26537064
Journal: Nature. 2015 Oct 8;526(7572):263-7.
Title: The genomic landscape of response to EGFR blockade in colorectal cancer.
Author: Bertotti, Andrea|Papp, Eniko|Jones, Sian|Adleff, Vilmos|Anagnostou, Valsamo|Lupo, Barbara|Sausen, Mark|Phallen, Jillian|Hruban, Carolyn A|Tokheim, Collin|Niknafs, Noushin|Nesselbush, Monica|Lytle, Karli|Sassi, Francesco|Cottino, Francesca|Migliardi, Giorg
PMID: 26416732
Journal: Neoplasma. 2015;62(6):855-63.
Title: MicroRNA-219-5p functions as a tumor suppressor partially by targeting platelet-derived growth factor receptor alpha in colorectal cancer.
Author: Xiong, G B|Zhang, G N|Xiao, Y|Niu, B Z|Qiu, H Z|Wu, B|Lin, G L|You, L|Shu, H
PMID: 26458304
Journal: J Clin Oncol. 2016 Apr 20;34(12):e107-9.
Title: Case of Rectal GI Stromal Tumor Demonstrating that KIT and PDGFRA Mutations Are Not Always Mutually Exclusive.
Author: Ricci, Riccardo|Martini, Maurizio|Cenci, Tonia|Antinori, Armando|Cassano, Alessandra|Larocca, Luigi M
PMID: 25024074
Journal: Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title: Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author: Pfarr, Nicole|Penzel, Roland|Klauschen, Frederick|Heim, Daniel|Brandt, Regine|Kazdal, Daniel|Jesinghaus, Moritz|Herpel, Esther|Schirmacher, Peter|Warth, Arne|Weichert, Wilko|Endris, Volker|Stenzinger, Albrecht
PMID: 27218826
Journal: Oncotarget. 2016 Nov 8;7(45):72908-72922.
Title: Genomic characterization of liver metastases from colorectal cancer patients.
Author: Sayagues, Jose Maria|Corchete, Luis Antonio|Gutierrez, Maria Laura|Sarasquete, Maria Eugenia|Del Mar Abad, Maria|Bengoechea, Oscar|Ferminan, Encarna|Anduaga, Maria Fernanda|Del Carmen, Sofia|Iglesias, Manuel|Esteban, Carmen|Angoso, Maria|Alcazar, Jose Ant
PMID: 27662660
Journal: Oncotarget. 2016 Dec 13;7(50):83270-83277.
Title: Targeted ultra-deep sequencing unveils a lack of driver-gene mutations linking non-hereditary gastrointestinal stromal tumors and highly prevalent second primary malignancies: random or nonrandom, that is the question.
Author: Lai, Bo-Ru|Wu, Yu-Tung|Kuo, Yung-Chia|Hsu, Hung-Chih|Chen, Jen-Shi|Chen, Tse-Ching|Wu, Ren-Chin|Chiu, Cheng-Tang|Yeh, Chun-Nan|Yeh, Ta-Sen
PMID: 27806309
Journal: World J Surg Oncol. 2016 Nov 14;14(1):285.
Title: Perivascular epithelioid cell tumor of the descending colon mimicking a gastrointestinal stromal tumor: a case report.
Author: Iwamoto, Ryuta|Kataoka, Tatsuki R|Furuhata, Ayako|Ono, Kazuo|Hirota, Seiichi|Kawada, Kenji|Sakai, Yoshiharu|Haga, Hironori
PMID: 27842558
Journal: Gan To Kagaku Ryoho. 2016 Nov;43(12):1800-1802.
Title: [A Case of Metastatic Colon Cancer Dramatically Affected by Anti-EGFR Antibody Therapy].
Author: Yagi, Ryoma|Shimada, Yoshifumi|Miura, Kohei|Tajima, Yosuke|Okamura, Takuma|Nakano, Masato|Ichikawa, Hiroshi|Nagahashi, Masayuki|Sakata, Jun|Kobayashi, Takashi|Kameyama, Hitoshi|Wakai, Toshifumi|Nogami, Hitoshi|Maruyama, Satoshi|Takii, Yasumasa
PMID: 28133136
Journal: Genes Chromosomes Cancer. 2017 Nov;56(11):769-787.
Title: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer.
Author: Slattery, Martha L|Herrick, Jennifer S|Mullany, Lila E|Samowitz, Wade S|Sevens, John R|Sakoda, Lori|Wolff, Roger K
PMID: 28675510
Journal: Oncotarget. 2017 Aug 24;8(55):93567-93579.
Title: Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.
Author: Shimada, Yoshifumi|Kameyama, Hitoshi|Nagahashi, Masayuki|Ichikawa, Hiroshi|Muneoka, Yusuke|Yagi, Ryoma|Tajima, Yosuke|Okamura, Takuma|Nakano, Masato|Sakata, Jun|Kobayashi, Takashi|Nogami, Hitoshi|Maruyama, Satoshi|Takii, Yasumasa|Hayashida, Tetsu|Takaishi
PMID: 29212173
Journal: Oncol Lett. 2017 Nov;14(5):5221-5228.
Title: Lack of microsatellite instability in gastrointestinal stromal tumors.
Author: Campanella, Nathalia C|Scapulatempo-Neto, Cristovam|Abrahao-Machado, Lucas Faria|Torres De Oliveira, Antonio Talvane|Berardinelli, Gustavo N|Guimaraes, Denise Peixoto|Reis, Rui M
PMID: 29113157
Journal: PLoS One. 2017 Aug 14;12(8):e0182265.
Title: Transcriptome analysis of PDGFRalpha+ cells identifies T-type Ca2+ channel CACNA1G as a new pathological marker for PDGFRalpha+ cell hyperplasia.
Author: Ha, Se Eun|Lee, Moon Young|Kurahashi, Masaaki|Wei, Lai|Jorgensen, Brian G|Park, Chanjae|Park, Paul J|Redelman, Doug|Sasse, Kent C|Becker, Laren S|Sanders, Kenton M|Ro, Seungil
PMID: 28806761
Journal: J Natl Cancer Inst. 2017 Aug 1;109(8). pii: 3064533.
Title: A Novel Diagnostic Tool for Selecting Patients With Mesenchymal-Type Colon Cancer Reveals Intratumor Subtype Heterogeneity.
Author: Ubink, Inge|Elias, Sjoerd G|Moelans, Cathy B|Lacle, Miangela M|van Grevenstein, Wilhelmina M U|van Diest, Paul J|Borel Rinkes, Inne H M|Kranenburg, Onno
PMID: 28376187
Journal: Mol Carcinog. 2018 Feb;57(2):243-261.
Title: The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer.
Author: Slattery, Martha L|Mullany, Lila E|Sakoda, Lori C|Wolff, Roger K|Stevens, John R|Samowitz, Wade S|Herrick, Jennifer S
PMID: 29068474
Journal: Transl Gastroenterol Hepatol. 2018 Feb 1;3:8.
Title: Management of rectal gastrointestinal stromal tumor.
Author: Kameyama, Hitoshi|Kanda, Tatsuo|Tajima, Yosuke|Shimada, Yoshifumi|Ichikawa, Hiroshi|Hanyu, Takaaki|Ishikawa, Takashi|Wakai, Toshifumi
PMID: 29552659
Journal: Cancer Inform. 2018 Mar 26;17:1176935118766522.
Title: The MAPK-Signaling Pathway in Colorectal Cancer: Dysregulated Genes and Their Association With MicroRNAs.
Author: Slattery, Martha L|Mullany, Lila E|Sakoda, Lori C|Wolff, Roger K|Samowitz, Wade S|Herrick, Jennifer S
PMID: 29636593
Journal: Cancer Control. 2018 Jan-Dec;25(1):1073274818789361.
Title: Lenvatinib: A Promising Molecular Targeted Agent for Multiple Cancers.
Author: Suyama, Koichi|Iwase, Hirotaka
PMID: 30032643
Journal: J Cancer Res Clin Oncol. 2018 Aug 31. pii: 10.1007/s00432-018-2742-1.
Title: The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing.
Author: Zou, Shuang-Mei|Li, Wei-Hua|Wang, Wen-Miao|Li, Wen-Bin|Shi, Su-Sheng|Ying, Jian-Ming|Lyu, Ning
PMID: 30171333
Journal: Cancer Cell Int. 2018 Sep 6;18:131.
Title: Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases.
Author: Fassan, Matteo|Vianello, Luca|Sacchi, Diana|Fanelli, Giuseppe N|Munari, Giada|Scarpa, Marco|Cappellesso, Rocco|Loupakis, Fotios|Lanza, Cristiano|Salmaso, Roberta|Mescoli, Claudia|Valeri, Nicola|Agostini, Marco|D'Angelo, Edoardo|Lonardi, Sara|Pucciarelli,
PMID: 30202242