Primary Site >> Colorectal Cancer
Gene >> PDGFRA
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Ref: Molecular dimensions of gastrointestinal tumors: some thoughts for digestion. PMID: 14518068 |
Ref: Novel potent orally active selective VEGFR-2 tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas. PMID: 15743179 |
Ref: Absence of tyrosine kinase mutations in Japanese colorectal cancer patients. PMID: 17016444 Ref: Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas. PMID: 17461467 Ref: Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. PMID: 17615082 |
Ref: Aberrant methylation status of known methylation-sensitive CpG islands in gastrointestinal stromal tumors without any correlation to the state of c-kit and PDGFRA gene mutations and their malignancy. PMID: 18271923 Ref: PDGFRalpha/beta expression correlates with the metastatic behavior of human colorectal cancer: a possible rationale for a molecular targeting strategy. PMID: 18288404 Ref: [Expression and clinical significance of PDGFRalpha and PDGFRbeta in colorectal cancer]. PMID: 18570744 |
Ref: Association of gastrointestinal stromal tumor and acute myeloid leukemia preceded by myelodysplastic syndrome with refractory anemia. PMID: 19579873 Ref: Gastrointestinal stromal tumor of the digestive organs: a histopathologic study of 31 cases in a single Japanese institute. PMID: 20126584 |
Ref: Hereditary gastrointestinal stromal tumors sharing the KIT Exon 17 germline mutation p.Asp820Tyr develop through different cytogenetic progression pathways. PMID: 19847891 Ref: K-ras mutation status correlates with the expression of VEGFR1, VEGFR2, and PDGFRalpha in colorectal cancer. PMID: 19936766 Ref: Tyrosine kinase expression in pulmonary metastases and paired primary tumors. PMID: 19948538 |
Ref: Hedgehog signaling drives cellular survival in human colon carcinoma cells. PMID: 21135115 |
Ref: Identification of differential gene expressions in colorectal cancer and polyp by cDNA microarray. PMID: 22363125 Ref: PDGFRalpha/beta and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome. PMID: 23146028 |
Ref: Histopathologic study of the rectum in 1,464 consecutive rectal specimens in a single Japanese hospital: II. malignant lesions. PMID: 23412998 Ref: Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types. PMID: 23637631 Ref: Inflammatory fibroid polyp of rectum mimicking rectal cancer. PMID: 23906237 |
Ref: Clinicopathologic factors predicting outcomes in patients with gastrointestinal stromal tumors of the rectum and colon. PMID: 24375257 Ref: The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study. PMID: 24700299 Ref: PDGF receptor-alpha promotes TGF-beta signaling in hepatic stellate cells via transcriptional and posttranscriptional regulation of TGF-beta receptors. PMID: 25169976 |
Ref: MiR-34a inhibits colon cancer proliferation and metastasis by inhibiting platelet-derived growth factor receptor alpha. PMID: 26324236 Ref: The genomic landscape of response to EGFR blockade in colorectal cancer. PMID: 26416732 Ref: MicroRNA-219-5p functions as a tumor suppressor partially by targeting platelet-derived growth factor receptor alpha in colorectal cancer. PMID: 26458304 Ref: Is there a correlation between peripheral blood expression of angiogenic transcriptional factors/receptors and colorectal cancer? PMID: 26537064 Ref: Regorafenib: Antitumor Activity upon Mono and Combination Therapy in Preclinical Pediatric Malignancy Models. PMID: 26599335 |
Ref: Case of Rectal GI Stromal Tumor Demonstrating that KIT and PDGFRA Mutations Are Not Always Mutually Exclusive. PMID: 25024074 Ref: Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases. PMID: 27218826 Ref: Genomic characterization of liver metastases from colorectal cancer patients. PMID: 27662660 Ref: Targeted ultra-deep sequencing unveils a lack of driver-gene mutations linking non-hereditary gastrointestinal stromal tumors and highly prevalent second primary malignancies: random or nonrandom, that is the question. PMID: 27806309 Ref: Perivascular epithelioid cell tumor of the descending colon mimicking a gastrointestinal stromal tumor: a case report. PMID: 27842558 Ref: [A Case of Metastatic Colon Cancer Dramatically Affected by Anti-EGFR Antibody Therapy]. PMID: 28133136 |
Ref: A Novel Diagnostic Tool for Selecting Patients With Mesenchymal-Type Colon Cancer Reveals Intratumor Subtype Heterogeneity. PMID: 28376187 Ref: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. PMID: 28675510 Ref: Transcriptome analysis of PDGFRalpha+ cells identifies T-type Ca2+ channel CACNA1G as a new pathological marker for PDGFRalpha+ cell hyperplasia. PMID: 28806761 Ref: Lack of microsatellite instability in gastrointestinal stromal tumors. PMID: 29113157 Ref: Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer. PMID: 29212173 |
Ref: The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer. PMID: 29068474 Ref: Management of rectal gastrointestinal stromal tumor. PMID: 29552659 Ref: The MAPK-Signaling Pathway in Colorectal Cancer: Dysregulated Genes and Their Association With MicroRNAs. PMID: 29636593 Ref: Lenvatinib: A Promising Molecular Targeted Agent for Multiple Cancers. PMID: 30032643 Ref: The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing. PMID: 30171333 Ref: Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases. PMID: 30202242 |