Primary Site >> Colorectal Cancer

Gene >> PDE10A

Journal: Oncogene. 2015 Mar 19;34(12):1499-509.
Title: Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and beta-catenin-dependent TCF transcriptional activity.
Author: Li, N|Lee, K|Xi, Y|Zhu, B|Gary, B D|Ramirez-Alcantara, V|Gurpinar, E|Canzoneri, J C|Fajardo, A|Sigler, S|Piazza, J T|Chen, X|Andrews, J|Thomas, M|Lu, W|Li, Y|Laan, D J|Moyer, M P|Russo, S|Eberhardt, B T|Yet, L|Keeton, A B|Grizzle, W E|Piazza, G A
PMID: 24704829
Journal: Oncotarget. 2016 Feb 2;7(5):5353-65.
Title: beta-catenin nuclear translocation in colorectal cancer cells is suppressed by PDE10A inhibition, cGMP elevation, and activation of PKG.
Author: Lee, Kevin|Lindsey, Ashley S|Li, Nan|Gary, Bernard|Andrews, Joel|Keeton, Adam B|Piazza, Gary A
PMID: 26713600