Primary Site >> Colorectal Cancer

Gene >> PDE10A

  • 2015
  • 2016
Ref: Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and beta-catenin-dependent TCF transcriptional activity.
PMID: 24704829
Ref: beta-catenin nuclear translocation in colorectal cancer cells is suppressed by PDE10A inhibition, cGMP elevation, and activation of PKG.
PMID: 26713600