Primary Site >> Colorectal Cancer
Gene >> MAP2K2
| 1. | |||||||||||
| Journal: | J Biol Chem. 2002 Oct 11;277(41):38205-11. | ||||||||||
| Title: | Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. | ||||||||||
| Author: | Fukuda, Ryo|Hirota, Kiichi|Fan, Fan|Jung, Young Do|Ellis, Lee M|Semenza, Gregg L | ||||||||||
| PMID: | 12149254 | ||||||||||
| 2. | |||||||||||
| Journal: | Anticancer Res. 2006 Mar-Apr;26(2A):1029-37. | ||||||||||
| Title: | EGF receptor-related protein (ERRP) inhibits invasion of colon cancer cells and tubule formation by endothelial cells in vitro. | ||||||||||
| Author: | Rishi, Arun K|Parikh, Rakesh|Wali, Anil|Durko, Lukasz|Zhang, Liyue|Yu, Yingjie|Majumdar, Adhip P N | ||||||||||
| PMID: | 16619503 | ||||||||||
| 3. | |||||||||||
| Journal: | Hum Mutat. 2008 Mar;29(3):441-50. | ||||||||||
| Title: | Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD). | ||||||||||
| Author: | Bentivegna, Steven|Zheng, Jianbiao|Namsaraev, Eugeni|Carlton, Victoria E H|Pavlicek, Adam|Moorhead, Martin|Siddiqui, Farooq|Wang, Zhiyong|Lee, Liana|Ireland, James S|Suyenaga, Kent|Willis, Thomas D|Faham, Malek|Seymour, Albert B | ||||||||||
| PMID: | 18186519 | ||||||||||
| 4. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2008 Aug 8;372(4):845-9. | ||||||||||
| Title: | Major contribution of MEK1 to the activation of ERK1/ERK2 and to the growth of LS174T colon carcinoma cells. | ||||||||||
| Author: | Shama, Jessica|Garcia-Medina, Raquel|Pouyssegur, Jacques|Vial, Emmanuel | ||||||||||
| PMID: | 18533112 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 2008 Dec 12;283(50):35295-304. | ||||||||||
| Title: | Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targets. | ||||||||||
| Author: | Yang, Lin|Zhang, Li|Wu, Qiuyu|Boyd, Douglas D | ||||||||||
| PMID: | 18940803 | ||||||||||
| 6. | |||||||||||
| Journal: | BMC Cancer. 2008 Nov 17;8:337. | ||||||||||
| Title: | Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors. | ||||||||||
| Author: | Voisin, Laure|Julien, Catherine|Duhamel, Stephanie|Gopalbhai, Kailesh|Claveau, Isabelle|Saba-El-Leil, Marc K|Rodrigue-Gervais, Ian Gael|Gaboury, Louis|Lamarre, Daniel|Basik, Mark|Meloche, Sylvain | ||||||||||
| PMID: | 19014680 | ||||||||||
| 7. | |||||||||||
| Journal: | PLoS One. 2009 May 27;4(5):e5717. | ||||||||||
| Title: | Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors. | ||||||||||
| Author: | Jaiswal, Bijay S|Janakiraman, Vasantharajan|Kljavin, Noelyn M|Eastham-Anderson, Jeffrey|Cupp, James E|Liang, Yuxin|Davis, David P|Hoeflich, Klaus P|Seshagiri, Somasekar | ||||||||||
| PMID: | 19492075 | ||||||||||
| 8. | |||||||||||
| Journal: | Sci Signal. 2011 Mar 29;4(166):ra17. | ||||||||||
| Title: | Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells. | ||||||||||
| Author: | Little, Annette S|Balmanno, Kathryn|Sale, Matthew J|Newman, Scott|Dry, Jonathan R|Hampson, Mark|Edwards, Paul A W|Smith, Paul D|Cook, Simon J | ||||||||||
| PMID: | 21447798 | ||||||||||
| 9. | |||||||||||
| Journal: | Sci Signal. 2011;4(170):er2. | ||||||||||
| Title: | A correction to the research article titled: "Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells" by A. S. Little, K. Balmanno, M. J. Sale, S. Newman, J. R. Dry, M. Hampson, P | ||||||||||
| Author: | Little, Annette S|Balmanno, Kathryn|Sale, Matthew J|Newman, Scott|Dry, Jonathan R|Hampson, Mark|Edwards, Paul A W|Smith, Paul D|Cook, Simon J | ||||||||||
| PMID: | 21674991 | ||||||||||
| 10. | |||||||||||
| Journal: | Inflamm Bowel Dis. 2012 Jan;18(1):94-100. | ||||||||||
| Title: | miR-143 and miR-145 are downregulated in ulcerative colitis: putative regulators of inflammation and protooncogenes. | ||||||||||
| Author: | Pekow, Joel R|Dougherty, Urszula|Mustafi, Reba|Zhu, Hongyan|Kocherginsky, Masha|Rubin, David T|Hanauer, Stephen B|Hart, John|Chang, Eugene B|Fichera, Alessandro|Joseph, Loren J|Bissonnette, Marc | ||||||||||
| PMID: | 21557394 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cancer Ther. 2012 Mar;11(3):720-9. | ||||||||||
| Title: | Comprehensive predictive biomarker analysis for MEK inhibitor GSK1120212. | ||||||||||
| Author: | Jing, Junping|Greshock, Joel|Holbrook, Joanna Dawn|Gilmartin, Aidan|Zhang, Xiping|McNeil, Elizabeth|Conway, Theresa|Moy, Christopher|Laquerre, Sylvie|Bachman, Kurt|Wooster, Richard|Degenhardt, Yan | ||||||||||
| PMID: | 22169769 | ||||||||||
| 12. | |||||||||||
| Journal: | Br J Cancer. 2013 Sep 17;109(6):1562-9. | ||||||||||
| Title: | Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI. | ||||||||||
| Author: | Beloueche-Babari, M|Jamin, Y|Arunan, V|Walker-Samuel, S|Revill, M|Smith, P D|Halliday, J|Waterton, J C|Barjat, H|Workman, P|Leach, M O|Robinson, S P | ||||||||||
| PMID: | 23942066 | ||||||||||
| 13. | |||||||||||
| Journal: | Clin Cancer Res. 2013 Nov 15;19(22):6219-29. | ||||||||||
| Title: | Overcoming IGF1R/IR resistance through inhibition of MEK signaling in colorectal cancer models. | ||||||||||
| Author: | Flanigan, Sara A|Pitts, Todd M|Newton, Timothy P|Kulikowski, Gillian N|Tan, Aik Choon|McManus, Martine C|Spreafico, Anna|Kachaeva, Maria I|Selby, Heather M|Tentler, John J|Eckhardt, S Gail|Leong, Stephen | ||||||||||
| PMID: | 24045180 | ||||||||||
| 14. | |||||||||||
| Journal: | Recent Results Cancer Res. 2014;201:241-8. | ||||||||||
| Title: | Trametinib. | ||||||||||
| Author: | Zeiser, Robert | ||||||||||
| PMID: | 24756797 | ||||||||||
| 15. | |||||||||||
| Journal: | Mol Nutr Food Res. 2016 Sep;60(9):1912-23. | ||||||||||
| Title: | Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis. | ||||||||||
| Author: | Kim, Hyemee|Banerjee, Nivedita|Ivanov, Ivan|Pfent, Catherine M|Prudhomme, Kalan R|Bisson, William H|Dashwood, Roderick H|Talcott, Stephen T|Mertens-Talcott, Susanne U | ||||||||||
| PMID: | 27028006 | ||||||||||
| 16. | |||||||||||
| Journal: | Mol Med Rep. 2017 Feb;15(2):867-872. | ||||||||||
| Title: | Identification of key genes in colorectal cancer using random walk with restart. | ||||||||||
| Author: | Cui, Xiaofeng|Shen, Kexin|Xie, Zhongshi|Liu, Tongjun|Zhang, Haishan | ||||||||||
| PMID: | 28000901 | ||||||||||
| 17. | |||||||||||
| Journal: | J Nutr Biochem. 2017 May;43:11-17. | ||||||||||
| Title: | A food-based approach that targets interleukin-6, a key regulator of chronic intestinal inflammation and colon carcinogenesis. | ||||||||||
| Author: | Sido, Abigail|Radhakrishnan, Sridhar|Kim, Sung Woo|Eriksson, Elisabeth|Shen, Frank|Li, Qunhua|Bhat, Vadiraja|Reddivari, Lavanya|Vanamala, Jairam K P | ||||||||||
| PMID: | 28193578 | ||||||||||
| 18. | |||||||||||
| Journal: | Cell Cycle. 2018 Nov 1. | ||||||||||
| Title: | Up-regulation of microRNA-497 inhibits the proliferation, migration and invasion but increases the apoptosis of multiple myeloma cells through the MAPK/ERK signaling pathway by targeting Raf-1. | ||||||||||
| Author: | Ye, Cheng-Yu|Zheng, Cui-Ping|Ying, Wei-Wei|Weng, Shan-Shan | ||||||||||
| PMID: | 30382763 | ||||||||||