Primary Site >> Colorectal Cancer

Gene >> EPHA2

Journal: Cancer Lett. 2002 Jan 25;175(2):187-95.
Title: Reduced expression of EphrinA1 (EFNA1) inhibits three-dimensional growth of HT29 colon carcinoma cells.
Author: Potla, Lyka|Boghaert, Erwin R|Armellino, Douglas|Frost, Philip|Damle, Nitin K
PMID: 11741747
Journal: J Cancer Res Clin Oncol. 2003 Dec;129(12):703-8. Epub 2003 Oct 15.
Title: EphA2 up-regulation induced by deoxycholic acid in human colon carcinoma cells, an involvement of extracellular signal-regulated kinase and p53-independence.
Author: Li, Zhongyou|Tanaka, Masamitsu|Kataoka, Hideki|Nakamura, Ritsuko|Sanjar, Ravshanov|Shinmura, Kazuya|Sugimura, Haruhiko
PMID: 14564515
Journal: Cancer Biol Ther. 2003 Sep-Oct;2(5):572-8.
Title: Apoptotic response to 5-fluorouracil treatment is mediated by reduced polyamines, non-autocrine Fas ligand and induced tumor necrosis factor receptor 2.
Author: Zhang, Wei|Ramdas, Latha|Shen, Weiping|Song, Sonya W|Hu, Limei|Hamilton, Stanley R
PMID: 14614330
Journal: Cancer Res. 2003 Dec 1;63(23):8476-80.
Title: EphA2 as target of anticancer immunotherapy: identification of HLA-A*0201-restricted epitopes.
Author: Alves, Pedro M S|Faure, Olivier|Graff-Dubois, Stephanie|Gross, David-Alexandre|Cornet, Sebastien|Chouaib, Salem|Miconnet, Isabelle|Lemonnier, Francois A|Kosmatopoulos, Kostas
PMID: 14679012
Journal: Oncol Rep. 2004 Mar;11(3):605-11.
Title: Expression of EphA2 and E-cadherin in colorectal cancer: correlation with cancer metastasis.
Author: Saito, Tetsuya|Masuda, Norihiro|Miyazaki, Tatsuya|Kanoh, Kenichi|Suzuki, Hideki|Shimura, Tatsuo|Asao, Takayuki|Kuwano, Hiroyuki
PMID: 14767510
Journal: Cancer Sci. 2004 Feb;95(2):136-41.
Title: Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer.
Author: Kataoka, Hideki|Igarashi, Hisaki|Kanamori, Masao|Ihara, Megumi|Wang, Jian-Dong|Wang, You-Jie|Li, Zhong-You|Shimamura, Takahiro|Kobayashi, Toshihiko|Maruyama, Keiji|Nakamura, Toshio|Arai, Hajime|Kajimura, Masayoshi|Hanai, Hiroyuki|Tanaka, Masamitsu|Sugimur
PMID: 14965363
Journal: Curr Cancer Drug Targets. 2005 May;5(3):149-57.
Title: EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics.
Author: Ireton, Renee C|Chen, Jin
PMID: 15892616
Journal: Oncogene. 2005 Nov 24;24(53):7859-68.
Title: A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis.
Author: Fang, Wei Bin|Brantley-Sieders, Dana M|Parker, Monica A|Reith, Alastair D|Chen, Jin
PMID: 16103880
Journal: Neoplasia. 2006 Jan;8(1):18-30.
Title: Anti-EphA2 antibodies decrease EphA2 protein levels in murine CT26 colorectal and human MDA-231 breast tumors but do not inhibit tumor growth.
Author: Kiewlich, David|Zhang, Jianhuan|Gross, Cynthia|Xia, Wei|Larsen, Brent|Cobb, Ronald R|Biroc, Sandra|Gu, Jian-Ming|Sato, Takashi|Light, David R|Heitner, Tara|Willuda, Joerg|Vogel, David|Monteclaro, Felipe|Citkowicz, Andrzej|Roffler, Steve R|Zajchowski, Debo
PMID: 16533422
Journal: Cancer. 2007 Oct 1;110(7):1469-77.
Title: Immunotherapy of murine colon cancer using receptor tyrosine kinase EphA2-derived peptide-pulsed dendritic cell vaccines.
Author: Yamaguchi, Shinjiro|Tatsumi, Tomohide|Takehara, Tetsuo|Sakamori, Ryotaro|Uemura, Akio|Mizushima, Tsunekazu|Ohkawa, Kazuyoshi|Storkus, Walter J|Hayashi, Norio
PMID: 17685394
Journal: Mol Cancer Res. 2007 Dec;5(12):1296-303.
Title: Inhibition of intestinal polyposis with reduced angiogenesis in ApcMin/+ mice due to decreases in c-Myc expression.
Author: Yekkala, Krishna|Baudino, Troy A
PMID: 18171987
Journal: Int J Cancer. 2009 Mar 15;124(6):1366-71.
Title: Loss of EphA2 receptor tyrosine kinase reduces ApcMin/+ tumorigenesis.
Author: Bogan, Christina|Chen, Jin|O'Sullivan, M Gerard|Cormier, Robert T
PMID: 19089910
Journal: Cancer Res. 2009 Mar 15;69(6):2279-86.
Title: Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells.
Author: Leroy, Cedric|Fialin, Camille|Sirvent, Audrey|Simon, Valerie|Urbach, Serge|Poncet, Joel|Robert, Bruno|Jouin, Patrick|Roche, Serge
PMID: 19276381
Journal: Dis Colon Rectum. 2009 Dec;52(12):2028-35.
Title: Prognostic role of vasculogenic mimicry in colorectal cancer.
Author: Baeten, Coen I M|Hillen, Femke|Pauwels, Patrick|de Bruine, Adriaan P|Baeten, Cor G M I
PMID: 19934926
Journal: Int J Cancer. 2010 May 1;126(9):2003-11.
Title: The role of Eph receptors and ephrin ligands in colorectal cancer.
Author: Herath, Nirmitha I|Boyd, Andrew W
PMID: 20039322
Journal: Cancer Immunol Immunother. 2010 May;59(5):759-67.
Title: EphA2-derived peptide vaccine with amphiphilic poly(gamma-glutamic acid) nanoparticles elicits an anti-tumor effect against mouse liver tumor.
Author: Yamaguchi, Shinjiro|Tatsumi, Tomohide|Takehara, Tetsuo|Sasakawa, Akira|Yamamoto, Masashi|Kohga, Keisuke|Miyagi, Takuya|Kanto, Tatsuya|Hiramastu, Naoki|Akagi, Takami|Akashi, Mitsuru|Hayashi, Norio
PMID: 19943047
Journal: Mol Cancer Res. 2011 Feb;9(2):149-60.
Title: EphA2 induces metastatic growth regulating amoeboid motility and clonogenic potential in prostate carcinoma cells.
Author: Taddei, Maria Letizia|Parri, Matteo|Angelucci, Adriano|Bianchini, Francesca|Marconi, Chiara|Giannoni, Elisa|Raugei, Giovanni|Bologna, Mauro|Calorini, Lido|Chiarugi, Paola
PMID: 21205836
Journal: J Pathol. 2011 Jul;224(3):377-88.
Title: FMNL2 is a positive regulator of cell motility and metastasis in colorectal carcinoma.
Author: Zhu, Xi-Ling|Zeng, Yuan-Feng|Guan, Jian|Li, Yu-Fa|Deng, Yong-Jian|Bian, Xiu-Wu|Ding, Yan-Qing|Liang, Li
PMID: 21506128
Journal: Eur J Cancer. 2012 Mar;48(5):753-62.
Title: Complex expression patterns of Eph receptor tyrosine kinases and their ephrin ligands in colorectal carcinogenesis.
Author: Herath, Nirmitha I|Spanevello, Mark D|Doecke, James D|Smith, Fiona M|Pouponnot, Celio|Boyd, Andrew W
PMID: 21852108
Journal: Int J Mol Sci. 2013 Nov 25;14(12):23231-43.
Title: The homeobox only protein homeobox (HOPX) and colorectal cancer.
Author: Yamashita, Keishi|Katoh, Hiroshi|Watanabe, Masahiko
PMID: 24287901
Journal: Nat Commun. 2014;5:3159.
Title: SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2.
Author: Naudin, Cecile|Sirvent, Audrey|Leroy, Cedric|Larive, Romain|Simon, Valerie|Pannequin, Julie|Bourgaux, Jean-Francois|Pierre, Josiane|Robert, Bruno|Hollande, Frederic|Roche, Serge
PMID: 24457997
Journal: Oncotarget. 2014 Oct 15;5(19):9199-213.
Title: Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy.
Author: Donnard, Elisa|Asprino, Paula F|Correa, Bruna R|Bettoni, Fabiana|Koyama, Fernanda C|Navarro, Fabio C P|Perez, Rodrigo O|Mariadason, John|Sieber, Oliver M|Strausberg, Robert L|Simpson, Andrew J G|Jardim, Denis L F|Reis, Luiz Fernando L|Parmigiani, Raphael
PMID: 25193853
Journal: PLoS One. 2015 Jul 15;10(7):e0132976.
Title: Isolation and Characterization of a Monobody with a Fibronectin Domain III Scaffold That Specifically Binds EphA2.
Author: Park, Seung-Hwan|Park, Sukho|Kim, Dong-Yeon|Pyo, Ayoung|Kimura, Richard H|Sathirachinda, Ataya|Choy, Hyon E|Min, Jung-Joon|Gambhir, Sanjiv Sam|Hong, Yeongjin
PMID: 26177208
Journal: Clin Cancer Res. 2016 Jan 1;22(1):230-242.
Title: EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer.
Author: Dunne, Philip D|Dasgupta, Sonali|Blayney, Jaine K|McArt, Darragh G|Redmond, Keara L|Weir, Jessica-Anne|Bradley, Conor A|Sasazuki, Takehiko|Shirasawa, Senji|Wang, Tingting|Srivastava, Supriya|Ong, Chee Wee|Arthur, Ken|Salto-Tellez, Manuel|Wilson, Richard H
PMID: 26283684
Journal: Biomed Res Int. 2016;2016:8208904.
Title: Expression of Migration-Related Genes in Human Colorectal Cancer and Activity of a Disintegrin and Metalloproteinase 17.
Author: Walkiewicz, Katarzyna|Koziel, Pawel|Bednarczyk, Martyna|Blazelonis, Adam|Mazurek, Urszula|Muc-Wierzgon, Malgorzata
PMID: 27110571
Journal: BMC Cancer. 2016 May 31;16:341.
Title: Cross-talk between the Tissue Factor/coagulation factor VIIa complex and the tyrosine kinase receptor EphA2 in cancer.
Author: Eriksson, Oskar|Thulin, Asa|Asplund, Anna|Hegde, Geeta|Navani, Sanjay|Siegbahn, Agneta
PMID: 27246245
Journal: Clin Cancer Res. 2017 Jan 1;23(1):159-170.
Title: Dysregulation of EGFR Pathway in EphA2 Cell Subpopulation Significantly Associates with Poor Prognosis in Colorectal Cancer.
Author: De Robertis, Mariangela|Loiacono, Luisa|Fusilli, Caterina|Poeta, Maria Luana|Mazza, Tommaso|Sanchez, Massimo|Marchionni, Luigi|Signori, Emanuela|Lamorte, Giuseppe|Vescovi, Angelo Luigi|Garcia-Foncillas, Jesus|Fazio, Vito Michele
PMID: 27401248
Journal: Int J Mol Sci. 2017 Feb 3;18(2). pii: ijms18020307.
Title: Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery.
Author: Stammes, Marieke A|Prevoo, Hendrica A J M|Ter Horst, Meyke C|Groot, Stephanie A|Van de Velde, Cornelis J H|Chan, Alan B|de Geus-Oei, Lioe-Fee|Kuppen, Peter J K|Vahrmeijer, Alexander L|Pasquale, Elena B|Sier, Cornelis F M
PMID: 28165374
Journal: Oncol Rep. 2017 Jul;38(1):263-270.
Title: EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells.
Author: Cuyas, Elisabet|Queralt, Bernardo|Martin-Castillo, Begona|Bosch-Barrera, Joaquim|Menendez, Javier A
PMID: 28560458
Journal: Oncotarget. 2017 Nov 1;8(61):104330-104346.
Title: EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner.
Author: Arabzadeh, Azadeh|McGregor, Kevin|Breton, Valerie|Van Der Kraak, Lauren|Akavia, Uri David|Greenwood, Celia M T|Beauchemin, Nicole
PMID: 29262644
Journal: Onco Targets Ther. 2018 Jul 2;11:3765-3774.
Title: Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer.
Author: Wang, Sen|Zhang, Zhiyuan|Qian, Wenwei|Ji, Dongjian|Wang, Qingyuan|Ji, Bing|Zhang, Yue|Zhang, Chuan|Sun, Ye|Zhu, Chunyan|Sun, Yueming
PMID: 29997437