Primary Site >> Colorectal Cancer
Gene >> EPHA2
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Ref: Reduced expression of EphrinA1 (EFNA1) inhibits three-dimensional growth of HT29 colon carcinoma cells. PMID: 11741747 |
Ref: EphA2 up-regulation induced by deoxycholic acid in human colon carcinoma cells, an involvement of extracellular signal-regulated kinase and p53-independence. PMID: 14564515 Ref: Apoptotic response to 5-fluorouracil treatment is mediated by reduced polyamines, non-autocrine Fas ligand and induced tumor necrosis factor receptor 2. PMID: 14614330 Ref: EphA2 as target of anticancer immunotherapy: identification of HLA-A*0201-restricted epitopes. PMID: 14679012 |
Ref: Expression of EphA2 and E-cadherin in colorectal cancer: correlation with cancer metastasis. PMID: 14767510 Ref: Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer. PMID: 14965363 |
Ref: EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics. PMID: 15892616 Ref: A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis. PMID: 16103880 |
Ref: Anti-EphA2 antibodies decrease EphA2 protein levels in murine CT26 colorectal and human MDA-231 breast tumors but do not inhibit tumor growth. PMID: 16533422 |
Ref: Immunotherapy of murine colon cancer using receptor tyrosine kinase EphA2-derived peptide-pulsed dendritic cell vaccines. PMID: 17685394 Ref: Inhibition of intestinal polyposis with reduced angiogenesis in ApcMin/+ mice due to decreases in c-Myc expression. PMID: 18171987 |
Ref: Loss of EphA2 receptor tyrosine kinase reduces ApcMin/+ tumorigenesis. PMID: 19089910 Ref: Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells. PMID: 19276381 Ref: Prognostic role of vasculogenic mimicry in colorectal cancer. PMID: 19934926 |
Ref: EphA2-derived peptide vaccine with amphiphilic poly(gamma-glutamic acid) nanoparticles elicits an anti-tumor effect against mouse liver tumor. PMID: 19943047 Ref: The role of Eph receptors and ephrin ligands in colorectal cancer. PMID: 20039322 |
Ref: EphA2 induces metastatic growth regulating amoeboid motility and clonogenic potential in prostate carcinoma cells. PMID: 21205836 Ref: FMNL2 is a positive regulator of cell motility and metastasis in colorectal carcinoma. PMID: 21506128 |
Ref: Complex expression patterns of Eph receptor tyrosine kinases and their ephrin ligands in colorectal carcinogenesis. PMID: 21852108 |
Ref: The homeobox only protein homeobox (HOPX) and colorectal cancer. PMID: 24287901 |
Ref: SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2. PMID: 24457997 Ref: Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy. PMID: 25193853 |
Ref: Isolation and Characterization of a Monobody with a Fibronectin Domain III Scaffold That Specifically Binds EphA2. PMID: 26177208 |
Ref: EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer. PMID: 26283684 Ref: Expression of Migration-Related Genes in Human Colorectal Cancer and Activity of a Disintegrin and Metalloproteinase 17. PMID: 27110571 Ref: Cross-talk between the Tissue Factor/coagulation factor VIIa complex and the tyrosine kinase receptor EphA2 in cancer. PMID: 27246245 |
Ref: Dysregulation of EGFR Pathway in EphA2 Cell Subpopulation Significantly Associates with Poor Prognosis in Colorectal Cancer. PMID: 27401248 Ref: Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery. PMID: 28165374 Ref: EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells. PMID: 28560458 Ref: EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner. PMID: 29262644 |
Ref: Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer. PMID: 29997437 |