Primary Site >> Pancreatic Cancer
Gene >> CDKN2A
| 1. | |||||||||||
| Journal: | Nat Genet. 1994 Sep;8(1):27-32. | ||||||||||
| Title: | Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. | ||||||||||
| Author: | Caldas, C|Hahn, S A|da Costa, L T|Redston, M S|Schutte, M|Seymour, A B|Weinstein, C L|Hruban, R H|Yeo, C J|Kern, S E | ||||||||||
| PMID: | 7726912 | ||||||||||
| 2. | |||||||||||
| Journal: | Melanoma Res. 1995 Jun;5(3):169-77. | ||||||||||
| Title: | CDKN2 explains part of the clinical phenotype in Dutch familial atypical multiple-mole melanoma (FAMMM) syndrome families. | ||||||||||
| Author: | Gruis, N A|Sandkuijl, L A|van der Velden, P A|Bergman, W|Frants, R R | ||||||||||
| PMID: | 7640518 | ||||||||||
| 3. | |||||||||||
| Journal: | N Engl J Med. 1995 Oct 12;333(15):970-4. | ||||||||||
| Title: | Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations. | ||||||||||
| Author: | Goldstein, A M|Fraser, M C|Struewing, J P|Hussussian, C J|Ranade, K|Zametkin, D P|Fontaine, L S|Organic, S M|Dracopoli, N C|Clark, W H Jr | ||||||||||
| PMID: | 7666916 | ||||||||||
| 4. | |||||||||||
| Journal: | N Engl J Med. 1995 Oct 12;333(15):975-7. | ||||||||||
| Title: | Brief report: a familial syndrome of pancreatic cancer and melanoma with a mutation in the CDKN2 tumor-suppressor gene. | ||||||||||
| Author: | Whelan, A J|Bartsch, D|Goodfellow, P J | ||||||||||
| PMID: | 7666917 | ||||||||||
| 5. | |||||||||||
| Journal: | Oncogene. 1995 Feb 2;10(3):619-22. | ||||||||||
| Title: | MTS-1 (CDKN2) tumor suppressor gene deletions are a frequent event in esophagus squamous cancer and pancreatic adenocarcinoma cell lines. | ||||||||||
| Author: | Liu, Q|Yan, Y X|McClure, M|Nakagawa, H|Fujimura, F|Rustgi, A K | ||||||||||
| PMID: | 7845688 | ||||||||||
| 6. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 1995 Nov;14(3):189-95. | ||||||||||
| Title: | Frequent mutations of CDKN2 in primary pancreatic adenocarcinomas. | ||||||||||
| Author: | Bartsch, D|Shevlin, D W|Tung, W S|Kisker, O|Wells, S A Jr|Goodfellow, P J | ||||||||||
| PMID: | 8589035 | ||||||||||
| 7. | |||||||||||
| Journal: | Gastroenterology. 1996 Apr;110(4):1215-24. | ||||||||||
| Title: | Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors. | ||||||||||
| Author: | Naumann, M|Savitskaia, N|Eilert, C|Schramm, A|Kalthoff, H|Schmiegel, W | ||||||||||
| PMID: | 8613012 | ||||||||||
| 8. | |||||||||||
| Journal: | Cell. 1996 Apr 5;85(1):27-37. | ||||||||||
| Title: | Role of the INK4a locus in tumor suppression and cell mortality. | ||||||||||
| Author: | Serrano, M|Lee, H|Chin, L|Cordon-Cardo, C|Beach, D|DePinho, R A | ||||||||||
| PMID: | 8620534 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Res. 1996 Mar 1;56(5):1083-90. | ||||||||||
| Title: | Gene deletion chemoselectivity: codeletion of the genes for p16(INK4), methylthioadenosine phosphorylase, and the alpha- and beta-interferons in human pancreatic cell carcinoma lines and its implications for chemotherapy. | ||||||||||
| Author: | Chen, Z H|Zhang, H|Savarese, T M | ||||||||||
| PMID: | 8640765 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Res. 1996 Mar 1;56(5):1137-41. | ||||||||||
| Title: | Deletion and mutation analyses of the P16/MTS-1 tumor suppressor gene in human ductal pancreatic cancer reveals a higher frequency of abnormalities in tumor-derived cell lines than in primary ductal adenocarcinomas. | ||||||||||
| Author: | Huang, L|Goodrow, T L|Zhang, S Y|Klein-Szanto, A J|Chang, H|Ruggeri, B A | ||||||||||
| PMID: | 8640773 | ||||||||||
| 11. | |||||||||||
| Journal: | J Med Genet. 1996 Nov;33(11):889-98. | ||||||||||
| Title: | Pancreatic adenocarcinoma: epidemiology and genetics. | ||||||||||
| Author: | Flanders, T Y|Foulkes, W D | ||||||||||
| PMID: | 8950667 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Res. 1996 Dec 15;56(24):5713-9. | ||||||||||
| Title: | Orthotopic xenografts of human pancreatic carcinomas acquire genetic aberrations during dissemination in nude mice. | ||||||||||
| Author: | Reyes, G|Villanueva, A|Garcia, C|Sancho, F J|Piulats, J|Lluis, F|Capella, G | ||||||||||
| PMID: | 8971180 | ||||||||||
| 13. | |||||||||||
| Journal: | Hua Xi Yi Ke Da Xue Xue Bao. 1996 Sep;27(3):258-60. | ||||||||||
| Title: | [Expression of P16 protein in pancreatic carcinoma]. | ||||||||||
| Author: | Hu, Y|Zhao, P|Wang, J|Zhang, S|Cheng, N|Yang, G | ||||||||||
| PMID: | 9389057 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncol Rep. 1996 Jul;3(4):743-5. | ||||||||||
| Title: | INK4 genes in pancreatic carcinoma. | ||||||||||
| Author: | Rozenblum, E|Schute, M|Kern, S | ||||||||||
| PMID: | 21594446 | ||||||||||
| 15. | |||||||||||
| Journal: | Am J Surg. 1997 Jan;173(1):37-41; discussion 42-3. | ||||||||||
| Title: | Advances in molecular genetics. | ||||||||||
| Author: | Lairmore, T C|Norton, J A | ||||||||||
| PMID: | 9046882 | ||||||||||
| 16. | |||||||||||
| Journal: | Cancer Res. 1997 May 1;57(9):1731-4. | ||||||||||
| Title: | Tumor-suppressive pathways in pancreatic carcinoma. | ||||||||||
| Author: | Rozenblum, E|Schutte, M|Goggins, M|Hahn, S A|Panzer, S|Zahurak, M|Goodman, S N|Sohn, T A|Hruban, R H|Yeo, C J|Kern, S E | ||||||||||
| PMID: | 9135016 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Res. 1997 Jun 1;57(11):2140-3. | ||||||||||
| Title: | p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma. | ||||||||||
| Author: | Moskaluk, C A|Hruban, R H|Kern, S E | ||||||||||
| PMID: | 9187111 | ||||||||||
| 18. | |||||||||||
| Journal: | J Clin Lab Anal. 1997;11(4):225-31. | ||||||||||
| Title: | Molecular diagnosis of pancreas carcinoma. | ||||||||||
| Author: | Chu, T M | ||||||||||
| PMID: | 9219065 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Res. 1997 Aug 1;57(15):3126-30. | ||||||||||
| Title: | Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas. | ||||||||||
| Author: | Schutte, M|Hruban, R H|Geradts, J|Maynard, R|Hilgers, W|Rabindran, S K|Moskaluk, C A|Hahn, S A|Schwarte-Waldhoff, I|Schmiegel, W|Baylin, S B|Kern, S E|Herman, J G | ||||||||||
| PMID: | 9242437 | ||||||||||
| 20. | |||||||||||
| Journal: | Nihon Geka Gakkai Zasshi. 1997 Jul;98(7):597-603. | ||||||||||
| Title: | [Molecular diagnosis of pancreatic cancer]. | ||||||||||
| Author: | Sugano, K | ||||||||||
| PMID: | 9276865 | ||||||||||
| 21. | |||||||||||
| Journal: | Mol Pharmacol. 1997 Nov;52(5):903-11. | ||||||||||
| Title: | Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis. | ||||||||||
| Author: | Chen, Z H|Olopade, O I|Savarese, T M | ||||||||||
| PMID: | 9351982 | ||||||||||
| 22. | |||||||||||
| Journal: | Surg Oncol. 1997;6(1):1-18. | ||||||||||
| Title: | The molecular genetics of pancreatic cancer. | ||||||||||
| Author: | Howe, J R|Conlon, K C | ||||||||||
| PMID: | 9364657 | ||||||||||
| 23. | |||||||||||
| Journal: | Digestion. 1997;58(6):550-6. | ||||||||||
| Title: | Molecular advances in pancreatic cancer. | ||||||||||
| Author: | Lemoine, N R | ||||||||||
| PMID: | 9438601 | ||||||||||
| 24. | |||||||||||
| Journal: | Digestion. 1997;58(6):564-9. | ||||||||||
| Title: | Hereditary pancreatitis and familial pancreatic cancer. | ||||||||||
| Author: | Finch, M D|Howes, N|Ellis, I|Mountford, R|Sutton, R|Raraty, M|Neoptolemos, J P | ||||||||||
| PMID: | 9438603 | ||||||||||
| 25. | |||||||||||
| Journal: | Clin Cancer Res. 1997 Sep;3(9):1473-7. | ||||||||||
| Title: | Frequent loss of p16 expression and its correlation with clinicopathological parameters in pancreatic carcinoma. | ||||||||||
| Author: | Hu, Y X|Watanabe, H|Ohtsubo, K|Yamaguchi, Y|Ha, A|Okai, T|Sawabu, N | ||||||||||
| PMID: | 9815833 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Res. 1998 Jan 15;58(2):237-40. | ||||||||||
| Title: | Genetic alterations in gastrinomas and nonfunctioning pancreatic neuroendocrine tumors: an analysis of p16/MTS1 tumor suppressor gene inactivation. | ||||||||||
| Author: | Muscarella, P|Melvin, W S|Fisher, W E|Foor, J|Ellison, E C|Herman, J G|Schirmer, W J|Hitchcock, C L|DeYoung, B R|Weghorst, C M | ||||||||||
| PMID: | 9443399 | ||||||||||
| 27. | |||||||||||
| Journal: | Surg Oncol Clin N Am. 1998 Jan;7(1):1-23. | ||||||||||
| Title: | Genetics of pancreatic cancer. From genes to families. | ||||||||||
| Author: | Hruban, R H|Petersen, G M|Ha, P K|Kern, S E | ||||||||||
| PMID: | 9443984 | ||||||||||
| 28. | |||||||||||
| Journal: | Int J Oncol. 1998 May;12(5):1111-6. | ||||||||||
| Title: | Aberrant p16INK4 expression related to clinical stage and prognosis in patients with pancreatic cancer. | ||||||||||
| Author: | Naka, T|Kobayashi, M|Ashida, K|Toyota, N|Kaneko, T|Kaibara, N | ||||||||||
| PMID: | 9538137 | ||||||||||
| 29. | |||||||||||
| Journal: | Cancer. 1998 May 1;82(9):1672-6. | ||||||||||
| Title: | The risk of subsequent primary carcinoma of the pancreas in patients with cutaneous malignant melanoma. | ||||||||||
| Author: | Schenk, M|Severson, R K|Pawlish, K S | ||||||||||
| PMID: | 9576287 | ||||||||||
| 30. | |||||||||||
| Journal: | J Invest Dermatol. 1998 May;110(5):788-92. | ||||||||||
| Title: | Excess cancer mortality in six Dutch pedigrees with the familial atypical multiple mole-melanoma syndrome from 1830 to 1994. | ||||||||||
| Author: | Hille, E T|van Duijn, E|Gruis, N A|Rosendaal, F R|Bergman, W|Vandenbroucke, J P | ||||||||||
| PMID: | 9579547 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer Res. 1998 Jun 1;58(11):2339-42. | ||||||||||
| Title: | Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene. | ||||||||||
| Author: | Su, G H|Hilgers, W|Shekher, M C|Tang, D J|Yeo, C J|Hruban, R H|Kern, S E | ||||||||||
| PMID: | 9622070 | ||||||||||
| 32. | |||||||||||
| Journal: | Langenbecks Arch Surg. 1998 Apr;383(2):105-15. | ||||||||||
| Title: | Molecular pattern of ductal pancreatic cancer. | ||||||||||
| Author: | Sirivatanauksorn, V|Sirivatanauksorn, Y|Lemoine, N R | ||||||||||
| PMID: | 9641882 | ||||||||||
| 33. | |||||||||||
| Journal: | Am J Pathol. 1998 Jul;153(1):263-9. | ||||||||||
| Title: | Comparative phenotypic studies of duct epithelial cell lines derived from normal human pancreas and pancreatic carcinoma. | ||||||||||
| Author: | Liu, N|Furukawa, T|Kobari, M|Tsao, M S | ||||||||||
| PMID: | 9665487 | ||||||||||
| 34. | |||||||||||
| Journal: | Pancreas. 1998 Jul;17(1):85-8. | ||||||||||
| Title: | Mutational analysis of the P16-binding domain of cyclin-dependent kinase 4 in tumors in the head region of the pancreas. | ||||||||||
| Author: | Ceha, H M|Clement, M J|Polak, M M|Offerhaus, G J|Slebos, R J | ||||||||||
| PMID: | 9667525 | ||||||||||
| 35. | |||||||||||
| Journal: | Mutat Res. 1998 May 25;400(1-2):421-37. | ||||||||||
| Title: | Accumulation of genetic alterations and their significance in each primary human cancer and cell line. | ||||||||||
| Author: | Murakami, Y|Sekiya, T | ||||||||||
| PMID: | 9685701 | ||||||||||
| 36. | |||||||||||
| Journal: | Digestion. 1998 Aug;59(5):493-501. | ||||||||||
| Title: | Recent discoveries in cancer genetics of exocrine pancreatic neoplasia. | ||||||||||
| Author: | Hahn, S A|Schmiegel, W H | ||||||||||
| PMID: | 9705534 | ||||||||||
| 37. | |||||||||||
| Journal: | Int J Oncol. 1998 Oct;13(4):669-76. | ||||||||||
| Title: | Alteration of the CDKN2A gene in pancreatic cancers: Is it a late event in the progression of pancreatic cancer? | ||||||||||
| Author: | Sugimoto, Y|Morita, R|Hikiji, K|Imura, G|Ogata, Y|Yasuda, D|Kono, A|Iguchi, H | ||||||||||
| PMID: | 9735394 | ||||||||||
| 38. | |||||||||||
| Journal: | Front Biosci. 1998 Nov 1;3:E230-7. | ||||||||||
| Title: | Gene therapy and pancreatic cancer. | ||||||||||
| Author: | Pearson, A S|Bouvet, M|Evans, D B|Roth, J A | ||||||||||
| PMID: | 9792901 | ||||||||||
| 39. | |||||||||||
| Journal: | Crit Rev Eukaryot Gene Expr. 1998;8(3-4):377-93. | ||||||||||
| Title: | The molecular and cellular biology of pancreatic cancer. | ||||||||||
| Author: | Perugini, R A|McDade, T P|Vittimberga, F J Jr|Callery, M P | ||||||||||
| PMID: | 9807701 | ||||||||||
| 40. | |||||||||||
| Journal: | J Gastrointest Surg. 1998 Jan-Feb;2(1):36-43. | ||||||||||
| Title: | A novel strategy for inhibiting growth of human pancreatic cancer cells by blocking cyclin-dependent kinase activity. | ||||||||||
| Author: | Iseki, H|Ko, T C|Xue, X Y|Seapan, A|Townsend, C M Jr | ||||||||||
| PMID: | 9841966 | ||||||||||
| 41. | |||||||||||
| Journal: | Hum Mutat. 1998;12(1):70. | ||||||||||
| Title: | Novel germline p16(INK4) allele (Asp145Cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148. Online. | ||||||||||
| Author: | Moskaluk, C A|Hruban, H|Lietman, A|Smyrk, T|Fusaro, L|Fusaro, R|Lynch, J|Yeo, C J|Jackson, C E|Lynch, H T|Kern, S E | ||||||||||
| PMID: | 10627132 | ||||||||||
| 42. | |||||||||||
| Journal: | Hum Mutat. 1998;12(3):212. | ||||||||||
| Title: | Five novel somatic CDKN2/p16 mutations identified in melanoma, glioma and carcinoma of the pancreas. Mutations in brief no. 170. Online. | ||||||||||
| Author: | Gretarsdottir, S|Olafsdottir, G H|Borg, A | ||||||||||
| PMID: | 10651484 | ||||||||||
| 43. | |||||||||||
| Journal: | Int J Oncol. 1999 Jan;14(1):93-101. | ||||||||||
| Title: | TGFbeta-induced growth inhibition involves cell cycle inhibitor p21 and pRb independent from p15 expression. | ||||||||||
| Author: | Voss, M|Wolff, B|Savitskaia, N|Ungefroren, H|Deppert, W|Schmiegel, W|Kalthoff, H|Naumann, M | ||||||||||
| PMID: | 9863014 | ||||||||||
| 44. | |||||||||||
| Journal: | Am J Pathol. 1999 Feb;154(2):525-36. | ||||||||||
| Title: | Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas. | ||||||||||
| Author: | Ghadimi, B M|Schrock, E|Walker, R L|Wangsa, D|Jauho, A|Meltzer, P S|Ried, T | ||||||||||
| PMID: | 10027410 | ||||||||||
| 45. | |||||||||||
| Journal: | Am J Surg. 1999 Jan;177(1):15-8. | ||||||||||
| Title: | Impact of p16 expression on surgical management of malignant melanoma and pancreatic carcinoma. | ||||||||||
| Author: | Bullock, G J|Green, J L|Baron, P L | ||||||||||
| PMID: | 10037301 | ||||||||||
| 46. | |||||||||||
| Journal: | Cancer. 1999 Feb 15;85(4):832-40. | ||||||||||
| Title: | Characterization of six cell lines established from human pancreatic adenocarcinomas. | ||||||||||
| Author: | Kato, M|Shimada, Y|Tanaka, H|Hosotani, R|Ohshio, G|Ishizaki, K|Imamura, M | ||||||||||
| PMID: | 10091760 | ||||||||||
| 47. | |||||||||||
| Journal: | Pancreas. 1999 Apr;18(3):308-15. | ||||||||||
| Title: | Immunohistochemical and molecular analysis of giant cell carcinoma of the pancreas: a report of three cases. | ||||||||||
| Author: | Imai, Y|Morishita, S|Ikeda, Y|Toyoda, M|Ashizawa, T|Yamamoto, K|Inoue, T|Ishikawa, T | ||||||||||
| PMID: | 10206490 | ||||||||||
| 48. | |||||||||||
| Journal: | Semin Radiat Oncol. 1999 Apr;9(2 Suppl 1):4-11. | ||||||||||
| Title: | Role of p53 and p16 gene alterations in determining response to concurrent paclitaxel and radiation in solid tumor. | ||||||||||
| Author: | King, T C|Estalilla, O C|Safran, H | ||||||||||
| PMID: | 10210535 | ||||||||||
| 49. | |||||||||||
| Journal: | Cancer. 1999 Jun 1;85(11):2352-8. | ||||||||||
| Title: | Malignant fibrous histiocytoma of the pancreas: a case report with genetic analysis. | ||||||||||
| Author: | Bastian, D|Ramaswamy, A|Barth, P J|Gerdes, B|Ernst, M|Bartsch, D | ||||||||||
| PMID: | 10357405 | ||||||||||
| 50. | |||||||||||
| Journal: | Eur J Surg. 1999 Apr;165(4):292-306. | ||||||||||
| Title: | Prognosis of human pancreatic adenocarcinoma: review of clinical and histopathological variables and possible uses of new molecular methods. | ||||||||||
| Author: | Eskelinen, M J|Haglund, U H | ||||||||||
| PMID: | 10365829 | ||||||||||
| 51. | |||||||||||
| Journal: | Ann N Y Acad Sci. 1999 Jun 30;880:74-82. | ||||||||||
| Title: | Molecular pathology of invasive carcinoma. | ||||||||||
| Author: | Longnecker, D S | ||||||||||
| PMID: | 10415852 | ||||||||||
| 52. | |||||||||||
| Journal: | Ann N Y Acad Sci. 1999 Jun 30;880:103-9. | ||||||||||
| Title: | Orthotopic models of human pancreatic cancer. | ||||||||||
| Author: | Capella, G|Farre, L|Villanueva, A|Reyes, G|Garcia, C|Tarafa, G|Lluis, F | ||||||||||
| PMID: | 10415855 | ||||||||||
| 53. | |||||||||||
| Journal: | Ann Oncol. 1999;10 Suppl 4:4-8. | ||||||||||
| Title: | Progress in cancer genetics: lessons from pancreatic cancer. | ||||||||||
| Author: | Goggins, M|Kern, S E|Offerhaus, J A|Hruban, R H | ||||||||||
| PMID: | 10436774 | ||||||||||
| 54. | |||||||||||
| Journal: | Ann Oncol. 1999;10 Suppl 4:9-11. | ||||||||||
| Title: | Pathology of incipient pancreatic cancer. | ||||||||||
| Author: | Hruban, R H|Wilentz, R E|Goggins, M|Offerhaus, G J|Yeo, C J|Kern, S E | ||||||||||
| PMID: | 10436775 | ||||||||||
| 55. | |||||||||||
| Journal: | Ann Oncol. 1999;10 Suppl 4:69-73. | ||||||||||
| Title: | Familial pancreatic cancer. | ||||||||||
| Author: | Hruban, R H|Petersen, G M|Goggins, M|Tersmette, A C|Offerhaus, G J|Falatko, F|Yeo, C J|Kern, S E | ||||||||||
| PMID: | 10436789 | ||||||||||
| 56. | |||||||||||
| Journal: | Ann Oncol. 1999;10 Suppl 4:153-6. | ||||||||||
| Title: | Biliopancreatic malignancy: screening the at risk patient with molecular markers. | ||||||||||
| Author: | Caldas, C | ||||||||||
| PMID: | 10436811 | ||||||||||
| 57. | |||||||||||
| Journal: | Ann Oncol. 1999;10 Suppl 4:285-90. | ||||||||||
| Title: | The future of surgery for pancreatic cancer. | ||||||||||
| Author: | Slavin, J|Ghaneh, P|Jones, L|Sutton, R|Hartley, M|Neoptolemos, J P | ||||||||||
| PMID: | 10436842 | ||||||||||
| 58. | |||||||||||
| Journal: | Oncogene. 1999 Jul 1;18(26):3810-20. | ||||||||||
| Title: | Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus. | ||||||||||
| Author: | Robertson, K D|Jones, P A | ||||||||||
| PMID: | 10445844 | ||||||||||
| 59. | |||||||||||
| Journal: | Cancer Gene Ther. 1999 Sep-Oct;6(5):428-36. | ||||||||||
| Title: | Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells. | ||||||||||
| Author: | Cascallo, M|Mercade, E|Capella, G|Lluis, F|Fillat, C|Gomez-Foix, A M|Mazo, A | ||||||||||
| PMID: | 10505853 | ||||||||||
| 60. | |||||||||||
| Journal: | Int J Cancer. 1999 Nov 12;83(4):441-8. | ||||||||||
| Title: | Characterization of ligurian melanoma families and risk of occurrence of other neoplasia. | ||||||||||
| Author: | Ghiorzo, P|Ciotti, P|Mantelli, M|Heouaine, A|Queirolo, P|Rainero, M L|Ferrari, C|Santi, P L|De Marchi, R|Farris, A|Ajmar, F|Bruzzi, P|Bianchi-Scarra, G | ||||||||||
| PMID: | 10508477 | ||||||||||
| 61. | |||||||||||
| Journal: | Cancer. 1999 Dec 1;86(11 Suppl):2464-77. | ||||||||||
| Title: | The genetics of hereditary melanoma and nevi. 1998 update. | ||||||||||
| Author: | Greene, M H | ||||||||||
| PMID: | 10630172 | ||||||||||
| 62. | |||||||||||
| Journal: | Clin Cancer Res. 1999 Dec;5(12):4182-5. | ||||||||||
| Title: | P16INK4a expression adenovirus vector to suppress pancreas cancer cell proliferation. | ||||||||||
| Author: | Kobayashi, S|Shirasawa, H|Sashiyama, H|Kawahira, H|Kaneko, K|Asano, T|Ochiai, T | ||||||||||
| PMID: | 10632358 | ||||||||||
| 63. | |||||||||||
| Journal: | Curr Opin Gastroenterol. 1999 Sep;15(5):404-9. | ||||||||||
| Title: | Molecular genetics and related developments in pancreatic cancer. | ||||||||||
| Author: | Hruban, R H|Goggins, M|Kern, S E | ||||||||||
| PMID: | 17023981 | ||||||||||
| 64. | |||||||||||
| Journal: | Cancer Treat Rev. 2000 Feb;26(1):29-52. | ||||||||||
| Title: | Molecular biology of pancreatic cancer; oncogenes, tumour suppressor genes, growth factors, and their receptors from a clinical perspective. | ||||||||||
| Author: | Sakorafas, G H|Tsiotou, A G|Tsiotos, G G | ||||||||||
| PMID: | 10660490 | ||||||||||
| 65. | |||||||||||
| Journal: | Cancer Res. 2000 Jan 15;60(2):409-16. | ||||||||||
| Title: | Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations. | ||||||||||
| Author: | Lal, G|Liu, G|Schmocker, B|Kaurah, P|Ozcelik, H|Narod, S A|Redston, M|Gallinger, S | ||||||||||
| PMID: | 10667595 | ||||||||||
| 66. | |||||||||||
| Journal: | Blood. 2000 Mar 1;95(5):1869-71. | ||||||||||
| Title: | Germline CDKN2A mutation implicated in predisposition to multiple myeloma. | ||||||||||
| Author: | Dilworth, D|Liu, L|Stewart, A K|Berenson, J R|Lassam, N|Hogg, D | ||||||||||
| PMID: | 10688850 | ||||||||||
| 67. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2000 Apr;27(4):358-61. | ||||||||||
| Title: | Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations. | ||||||||||
| Author: | Lal, G|Liu, L|Hogg, D|Lassam, N J|Redston, M S|Gallinger, S | ||||||||||
| PMID: | 10719365 | ||||||||||
| 68. | |||||||||||
| Journal: | Nihon Geka Gakkai Zasshi. 2000 Feb;101(2):233-6. | ||||||||||
| Title: | [General rules for the study of pancreatic cancer by molecular biological aspect]. | ||||||||||
| Author: | Omata, M|Tada, M | ||||||||||
| PMID: | 10734643 | ||||||||||
| 69. | |||||||||||
| Journal: | Cancer Res. 2000 Apr 1;60(7):1835-9. | ||||||||||
| Title: | Hypermethylation of multiple genes in pancreatic adenocarcinoma. | ||||||||||
| Author: | Ueki, T|Toyota, M|Sohn, T|Yeo, C J|Issa, J P|Hruban, R H|Goggins, M | ||||||||||
| PMID: | 10766168 | ||||||||||
| 70. | |||||||||||
| Journal: | J Surg Res. 2000 May 1;90(1):39-44. | ||||||||||
| Title: | Pancreatic cancer cell proliferation is phosphatidylinositol 3-kinase dependent. | ||||||||||
| Author: | Perugini, R A|McDade, T P|Vittimberga, F J Jr|Callery, M P | ||||||||||
| PMID: | 10781373 | ||||||||||
| 71. | |||||||||||
| Journal: | J Natl Cancer Inst. 2000 Jun 21;92(12):1006-10. | ||||||||||
| Title: | Genotype-phenotype relationships in U.S. melanoma-prone families with CDKN2A and CDK4 mutations. | ||||||||||
| Author: | Goldstein, A M|Struewing, J P|Chidambaram, A|Fraser, M C|Tucker, M A | ||||||||||
| PMID: | 10861313 | ||||||||||
| 72. | |||||||||||
| Journal: | Am J Pathol. 2000 Jul;157(1):83-92. | ||||||||||
| Title: | Molecular analysis of microdissected tumors and preneoplastic intraductal lesions in pancreatic carcinoma. | ||||||||||
| Author: | Heinmoller, E|Dietmaier, W|Zirngibl, H|Heinmoller, P|Scaringe, W|Jauch, K W|Hofstadter, F|Ruschoff, J | ||||||||||
| PMID: | 10880379 | ||||||||||
| 73. | |||||||||||
| Journal: | J Natl Cancer Inst. 2000 Aug 2;92(15):1260-6. | ||||||||||
| Title: | High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families. | ||||||||||
| Author: | Borg, A|Sandberg, T|Nilsson, K|Johannsson, O|Klinker, M|Masback, A|Westerdahl, J|Olsson, H|Ingvar, C | ||||||||||
| PMID: | 10922411 | ||||||||||
| 74. | |||||||||||
| Journal: | Appl Immunohistochem Mol Morphol. 2000 Mar;8(1):71-9. | ||||||||||
| Title: | Immunohistochemical p16INK4a analysis of archival tumors with deletion, hypermethylation, or mutation of the CDKN2/MTS1 gene. A comparison of four commercial antibodies. | ||||||||||
| Author: | Geradts, J|Hruban, R H|Schutte, M|Kern, S E|Maynard, R | ||||||||||
| PMID: | 10937052 | ||||||||||
| 75. | |||||||||||
| Journal: | Am J Gastroenterol. 2000 Aug;95(8):2080-5. | ||||||||||
| Title: | Association of poor prognosis with loss of 12q, 17p, and 18q, and concordant loss of 6q/17p and 12q/18q in human pancreatic ductal adenocarcinoma. | ||||||||||
| Author: | Yatsuoka, T|Sunamura, M|Furukawa, T|Fukushige, S|Yokoyama, T|Inoue, H|Shibuya, K|Takeda, K|Matsuno, S|Horii, A | ||||||||||
| PMID: | 10950061 | ||||||||||
| 76. | |||||||||||
| Journal: | Int J Cancer. 2000 Sep 15;87(6):809-11. | ||||||||||
| Title: | Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden). | ||||||||||
| Author: | Vasen, H F|Gruis, N A|Frants, R R|van Der Velden, P A|Hille, E T|Bergman, W | ||||||||||
| PMID: | 10956390 | ||||||||||
| 77. | |||||||||||
| Journal: | Cancer Lett. 2000 Oct 31;159(2):151-8. | ||||||||||
| Title: | Inhibition of pRb phosphorylation and cell cycle progression by an antennapedia-p16(INK4A) fusion peptide in pancreatic cancer cells. | ||||||||||
| Author: | Fujimoto, K|Hosotani, R|Miyamoto, Y|Doi, R|Koshiba, T|Otaka, A|Fujii, N|Beauchamp, R D|Imamura, M | ||||||||||
| PMID: | 10996726 | ||||||||||
| 78. | |||||||||||
| Journal: | Hum Mutat. 2000 Nov;16(5):447-8. | ||||||||||
| Title: | A novel germline mutation, P48T, in the CDKN2A/p16 gene in a patient with pancreatic carcinoma. | ||||||||||
| Author: | Moore, P S|Zamboni, G|Falconi, M|Bassi, C|Scarpa, A | ||||||||||
| PMID: | 11058911 | ||||||||||
| 79. | |||||||||||
| Journal: | Pancreas. 2000 Nov;21(4):369-75. | ||||||||||
| Title: | Multiple primary tumors as an indicator for p16INK4a germline mutations in pancreatic cancer patients? | ||||||||||
| Author: | Gerdes, B|Bartsch, D K|Ramaswamy, A|Kersting, M|Wild, A|Schuermann, M|Frey, M|Rothmund, M | ||||||||||
| PMID: | 11075991 | ||||||||||
| 80. | |||||||||||
| Journal: | Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2000 Dec;17(6):399-403. | ||||||||||
| Title: | [Study on the relationship of alteration and expression of p16 gene to pancreatic carcinoma]. | ||||||||||
| Author: | Zhou, J|Yang, D|Zhang, L|Wang, J|Yao, Q|Su, Z|Fan, Y | ||||||||||
| PMID: | 11110976 | ||||||||||
| 81. | |||||||||||
| Journal: | Gastroenterology. 2000 Dec;119(6):1756-60. | ||||||||||
| Title: | Genetic counseling and testing for germline p16 mutations in two pancreatic cancer-prone families. | ||||||||||
| Author: | Lynch, H T|Brand, R E|Lynch, J F|Fusaro, R M|Smyrk, T C|Goggins, M|Kern, S E | ||||||||||
| PMID: | 11113097 | ||||||||||
| 82. | |||||||||||
| Journal: | Cell Biochem Biophys. 2000;33(2):189-97. | ||||||||||
| Title: | The physiology of p16(INK4A)-mediated G1 proliferative arrest. | ||||||||||
| Author: | Shapiro, G I|Edwards, C D|Rollins, B J | ||||||||||
| PMID: | 11325039 | ||||||||||
| 83. | |||||||||||
| Journal: | Zhonghua Wai Ke Za Zhi. 2000 Jun;38(6):457-9. | ||||||||||
| Title: | |||||||||||