Primary Site >> Pancreatic Cancer

Gene >> CDKN2A

Journal: Nat Genet. 1994 Sep;8(1):27-32.
Title: Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma.
Author: Caldas, C|Hahn, S A|da Costa, L T|Redston, M S|Schutte, M|Seymour, A B|Weinstein, C L|Hruban, R H|Yeo, C J|Kern, S E
PMID: 7726912
Journal: Melanoma Res. 1995 Jun;5(3):169-77.
Title: CDKN2 explains part of the clinical phenotype in Dutch familial atypical multiple-mole melanoma (FAMMM) syndrome families.
Author: Gruis, N A|Sandkuijl, L A|van der Velden, P A|Bergman, W|Frants, R R
PMID: 7640518
Journal: N Engl J Med. 1995 Oct 12;333(15):970-4.
Title: Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations.
Author: Goldstein, A M|Fraser, M C|Struewing, J P|Hussussian, C J|Ranade, K|Zametkin, D P|Fontaine, L S|Organic, S M|Dracopoli, N C|Clark, W H Jr
PMID: 7666916
Journal: N Engl J Med. 1995 Oct 12;333(15):975-7.
Title: Brief report: a familial syndrome of pancreatic cancer and melanoma with a mutation in the CDKN2 tumor-suppressor gene.
Author: Whelan, A J|Bartsch, D|Goodfellow, P J
PMID: 7666917
Journal: Oncogene. 1995 Feb 2;10(3):619-22.
Title: MTS-1 (CDKN2) tumor suppressor gene deletions are a frequent event in esophagus squamous cancer and pancreatic adenocarcinoma cell lines.
Author: Liu, Q|Yan, Y X|McClure, M|Nakagawa, H|Fujimura, F|Rustgi, A K
PMID: 7845688
Journal: Genes Chromosomes Cancer. 1995 Nov;14(3):189-95.
Title: Frequent mutations of CDKN2 in primary pancreatic adenocarcinomas.
Author: Bartsch, D|Shevlin, D W|Tung, W S|Kisker, O|Wells, S A Jr|Goodfellow, P J
PMID: 8589035
Journal: Gastroenterology. 1996 Apr;110(4):1215-24.
Title: Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors.
Author: Naumann, M|Savitskaia, N|Eilert, C|Schramm, A|Kalthoff, H|Schmiegel, W
PMID: 8613012
Journal: Cell. 1996 Apr 5;85(1):27-37.
Title: Role of the INK4a locus in tumor suppression and cell mortality.
Author: Serrano, M|Lee, H|Chin, L|Cordon-Cardo, C|Beach, D|DePinho, R A
PMID: 8620534
Journal: Cancer Res. 1996 Mar 1;56(5):1083-90.
Title: Gene deletion chemoselectivity: codeletion of the genes for p16(INK4), methylthioadenosine phosphorylase, and the alpha- and beta-interferons in human pancreatic cell carcinoma lines and its implications for chemotherapy.
Author: Chen, Z H|Zhang, H|Savarese, T M
PMID: 8640765
Journal: Cancer Res. 1996 Mar 1;56(5):1137-41.
Title: Deletion and mutation analyses of the P16/MTS-1 tumor suppressor gene in human ductal pancreatic cancer reveals a higher frequency of abnormalities in tumor-derived cell lines than in primary ductal adenocarcinomas.
Author: Huang, L|Goodrow, T L|Zhang, S Y|Klein-Szanto, A J|Chang, H|Ruggeri, B A
PMID: 8640773
Journal: J Med Genet. 1996 Nov;33(11):889-98.
Title: Pancreatic adenocarcinoma: epidemiology and genetics.
Author: Flanders, T Y|Foulkes, W D
PMID: 8950667
Journal: Cancer Res. 1996 Dec 15;56(24):5713-9.
Title: Orthotopic xenografts of human pancreatic carcinomas acquire genetic aberrations during dissemination in nude mice.
Author: Reyes, G|Villanueva, A|Garcia, C|Sancho, F J|Piulats, J|Lluis, F|Capella, G
PMID: 8971180
Journal: Hua Xi Yi Ke Da Xue Xue Bao. 1996 Sep;27(3):258-60.
Title: [Expression of P16 protein in pancreatic carcinoma].
Author: Hu, Y|Zhao, P|Wang, J|Zhang, S|Cheng, N|Yang, G
PMID: 9389057
Journal: Oncol Rep. 1996 Jul;3(4):743-5.
Title: INK4 genes in pancreatic carcinoma.
Author: Rozenblum, E|Schute, M|Kern, S
PMID: 21594446
Journal: Am J Surg. 1997 Jan;173(1):37-41; discussion 42-3.
Title: Advances in molecular genetics.
Author: Lairmore, T C|Norton, J A
PMID: 9046882
Journal: Cancer Res. 1997 May 1;57(9):1731-4.
Title: Tumor-suppressive pathways in pancreatic carcinoma.
Author: Rozenblum, E|Schutte, M|Goggins, M|Hahn, S A|Panzer, S|Zahurak, M|Goodman, S N|Sohn, T A|Hruban, R H|Yeo, C J|Kern, S E
PMID: 9135016
Journal: Cancer Res. 1997 Jun 1;57(11):2140-3.
Title: p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma.
Author: Moskaluk, C A|Hruban, R H|Kern, S E
PMID: 9187111
Journal: J Clin Lab Anal. 1997;11(4):225-31.
Title: Molecular diagnosis of pancreas carcinoma.
Author: Chu, T M
PMID: 9219065
Journal: Cancer Res. 1997 Aug 1;57(15):3126-30.
Title: Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas.
Author: Schutte, M|Hruban, R H|Geradts, J|Maynard, R|Hilgers, W|Rabindran, S K|Moskaluk, C A|Hahn, S A|Schwarte-Waldhoff, I|Schmiegel, W|Baylin, S B|Kern, S E|Herman, J G
PMID: 9242437
Journal: Nihon Geka Gakkai Zasshi. 1997 Jul;98(7):597-603.
Title: [Molecular diagnosis of pancreatic cancer].
Author: Sugano, K
PMID: 9276865
Journal: Mol Pharmacol. 1997 Nov;52(5):903-11.
Title: Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis.
Author: Chen, Z H|Olopade, O I|Savarese, T M
PMID: 9351982
Journal: Surg Oncol. 1997;6(1):1-18.
Title: The molecular genetics of pancreatic cancer.
Author: Howe, J R|Conlon, K C
PMID: 9364657
Journal: Digestion. 1997;58(6):550-6.
Title: Molecular advances in pancreatic cancer.
Author: Lemoine, N R
PMID: 9438601
Journal: Digestion. 1997;58(6):564-9.
Title: Hereditary pancreatitis and familial pancreatic cancer.
Author: Finch, M D|Howes, N|Ellis, I|Mountford, R|Sutton, R|Raraty, M|Neoptolemos, J P
PMID: 9438603
Journal: Clin Cancer Res. 1997 Sep;3(9):1473-7.
Title: Frequent loss of p16 expression and its correlation with clinicopathological parameters in pancreatic carcinoma.
Author: Hu, Y X|Watanabe, H|Ohtsubo, K|Yamaguchi, Y|Ha, A|Okai, T|Sawabu, N
PMID: 9815833
Journal: Cancer Res. 1998 Jan 15;58(2):237-40.
Title: Genetic alterations in gastrinomas and nonfunctioning pancreatic neuroendocrine tumors: an analysis of p16/MTS1 tumor suppressor gene inactivation.
Author: Muscarella, P|Melvin, W S|Fisher, W E|Foor, J|Ellison, E C|Herman, J G|Schirmer, W J|Hitchcock, C L|DeYoung, B R|Weghorst, C M
PMID: 9443399
Journal: Surg Oncol Clin N Am. 1998 Jan;7(1):1-23.
Title: Genetics of pancreatic cancer. From genes to families.
Author: Hruban, R H|Petersen, G M|Ha, P K|Kern, S E
PMID: 9443984
Journal: Int J Oncol. 1998 May;12(5):1111-6.
Title: Aberrant p16INK4 expression related to clinical stage and prognosis in patients with pancreatic cancer.
Author: Naka, T|Kobayashi, M|Ashida, K|Toyota, N|Kaneko, T|Kaibara, N
PMID: 9538137
Journal: Cancer. 1998 May 1;82(9):1672-6.
Title: The risk of subsequent primary carcinoma of the pancreas in patients with cutaneous malignant melanoma.
Author: Schenk, M|Severson, R K|Pawlish, K S
PMID: 9576287
Journal: J Invest Dermatol. 1998 May;110(5):788-92.
Title: Excess cancer mortality in six Dutch pedigrees with the familial atypical multiple mole-melanoma syndrome from 1830 to 1994.
Author: Hille, E T|van Duijn, E|Gruis, N A|Rosendaal, F R|Bergman, W|Vandenbroucke, J P
PMID: 9579547
Journal: Cancer Res. 1998 Jun 1;58(11):2339-42.
Title: Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene.
Author: Su, G H|Hilgers, W|Shekher, M C|Tang, D J|Yeo, C J|Hruban, R H|Kern, S E
PMID: 9622070
Journal: Langenbecks Arch Surg. 1998 Apr;383(2):105-15.
Title: Molecular pattern of ductal pancreatic cancer.
Author: Sirivatanauksorn, V|Sirivatanauksorn, Y|Lemoine, N R
PMID: 9641882
Journal: Am J Pathol. 1998 Jul;153(1):263-9.
Title: Comparative phenotypic studies of duct epithelial cell lines derived from normal human pancreas and pancreatic carcinoma.
Author: Liu, N|Furukawa, T|Kobari, M|Tsao, M S
PMID: 9665487
Journal: Pancreas. 1998 Jul;17(1):85-8.
Title: Mutational analysis of the P16-binding domain of cyclin-dependent kinase 4 in tumors in the head region of the pancreas.
Author: Ceha, H M|Clement, M J|Polak, M M|Offerhaus, G J|Slebos, R J
PMID: 9667525
Journal: Mutat Res. 1998 May 25;400(1-2):421-37.
Title: Accumulation of genetic alterations and their significance in each primary human cancer and cell line.
Author: Murakami, Y|Sekiya, T
PMID: 9685701
Journal: Digestion. 1998 Aug;59(5):493-501.
Title: Recent discoveries in cancer genetics of exocrine pancreatic neoplasia.
Author: Hahn, S A|Schmiegel, W H
PMID: 9705534
Journal: Int J Oncol. 1998 Oct;13(4):669-76.
Title: Alteration of the CDKN2A gene in pancreatic cancers: Is it a late event in the progression of pancreatic cancer?
Author: Sugimoto, Y|Morita, R|Hikiji, K|Imura, G|Ogata, Y|Yasuda, D|Kono, A|Iguchi, H
PMID: 9735394
Journal: Front Biosci. 1998 Nov 1;3:E230-7.
Title: Gene therapy and pancreatic cancer.
Author: Pearson, A S|Bouvet, M|Evans, D B|Roth, J A
PMID: 9792901
Journal: Crit Rev Eukaryot Gene Expr. 1998;8(3-4):377-93.
Title: The molecular and cellular biology of pancreatic cancer.
Author: Perugini, R A|McDade, T P|Vittimberga, F J Jr|Callery, M P
PMID: 9807701
Journal: J Gastrointest Surg. 1998 Jan-Feb;2(1):36-43.
Title: A novel strategy for inhibiting growth of human pancreatic cancer cells by blocking cyclin-dependent kinase activity.
Author: Iseki, H|Ko, T C|Xue, X Y|Seapan, A|Townsend, C M Jr
PMID: 9841966
Journal: Hum Mutat. 1998;12(1):70.
Title: Novel germline p16(INK4) allele (Asp145Cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148. Online.
Author: Moskaluk, C A|Hruban, H|Lietman, A|Smyrk, T|Fusaro, L|Fusaro, R|Lynch, J|Yeo, C J|Jackson, C E|Lynch, H T|Kern, S E
PMID: 10627132
Journal: Hum Mutat. 1998;12(3):212.
Title: Five novel somatic CDKN2/p16 mutations identified in melanoma, glioma and carcinoma of the pancreas. Mutations in brief no. 170. Online.
Author: Gretarsdottir, S|Olafsdottir, G H|Borg, A
PMID: 10651484
Journal: Int J Oncol. 1999 Jan;14(1):93-101.
Title: TGFbeta-induced growth inhibition involves cell cycle inhibitor p21 and pRb independent from p15 expression.
Author: Voss, M|Wolff, B|Savitskaia, N|Ungefroren, H|Deppert, W|Schmiegel, W|Kalthoff, H|Naumann, M
PMID: 9863014
Journal: Am J Pathol. 1999 Feb;154(2):525-36.
Title: Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas.
Author: Ghadimi, B M|Schrock, E|Walker, R L|Wangsa, D|Jauho, A|Meltzer, P S|Ried, T
PMID: 10027410
Journal: Am J Surg. 1999 Jan;177(1):15-8.
Title: Impact of p16 expression on surgical management of malignant melanoma and pancreatic carcinoma.
Author: Bullock, G J|Green, J L|Baron, P L
PMID: 10037301
Journal: Cancer. 1999 Feb 15;85(4):832-40.
Title: Characterization of six cell lines established from human pancreatic adenocarcinomas.
Author: Kato, M|Shimada, Y|Tanaka, H|Hosotani, R|Ohshio, G|Ishizaki, K|Imamura, M
PMID: 10091760
Journal: Pancreas. 1999 Apr;18(3):308-15.
Title: Immunohistochemical and molecular analysis of giant cell carcinoma of the pancreas: a report of three cases.
Author: Imai, Y|Morishita, S|Ikeda, Y|Toyoda, M|Ashizawa, T|Yamamoto, K|Inoue, T|Ishikawa, T
PMID: 10206490
Journal: Semin Radiat Oncol. 1999 Apr;9(2 Suppl 1):4-11.
Title: Role of p53 and p16 gene alterations in determining response to concurrent paclitaxel and radiation in solid tumor.
Author: King, T C|Estalilla, O C|Safran, H
PMID: 10210535
Journal: Cancer. 1999 Jun 1;85(11):2352-8.
Title: Malignant fibrous histiocytoma of the pancreas: a case report with genetic analysis.
Author: Bastian, D|Ramaswamy, A|Barth, P J|Gerdes, B|Ernst, M|Bartsch, D
PMID: 10357405
Journal: Eur J Surg. 1999 Apr;165(4):292-306.
Title: Prognosis of human pancreatic adenocarcinoma: review of clinical and histopathological variables and possible uses of new molecular methods.
Author: Eskelinen, M J|Haglund, U H
PMID: 10365829
Journal: Ann N Y Acad Sci. 1999 Jun 30;880:74-82.
Title: Molecular pathology of invasive carcinoma.
Author: Longnecker, D S
PMID: 10415852
Journal: Ann N Y Acad Sci. 1999 Jun 30;880:103-9.
Title: Orthotopic models of human pancreatic cancer.
Author: Capella, G|Farre, L|Villanueva, A|Reyes, G|Garcia, C|Tarafa, G|Lluis, F
PMID: 10415855
Journal: Ann Oncol. 1999;10 Suppl 4:4-8.
Title: Progress in cancer genetics: lessons from pancreatic cancer.
Author: Goggins, M|Kern, S E|Offerhaus, J A|Hruban, R H
PMID: 10436774
Journal: Ann Oncol. 1999;10 Suppl 4:9-11.
Title: Pathology of incipient pancreatic cancer.
Author: Hruban, R H|Wilentz, R E|Goggins, M|Offerhaus, G J|Yeo, C J|Kern, S E
PMID: 10436775
Journal: Ann Oncol. 1999;10 Suppl 4:69-73.
Title: Familial pancreatic cancer.
Author: Hruban, R H|Petersen, G M|Goggins, M|Tersmette, A C|Offerhaus, G J|Falatko, F|Yeo, C J|Kern, S E
PMID: 10436789
Journal: Ann Oncol. 1999;10 Suppl 4:153-6.
Title: Biliopancreatic malignancy: screening the at risk patient with molecular markers.
Author: Caldas, C
PMID: 10436811
Journal: Ann Oncol. 1999;10 Suppl 4:285-90.
Title: The future of surgery for pancreatic cancer.
Author: Slavin, J|Ghaneh, P|Jones, L|Sutton, R|Hartley, M|Neoptolemos, J P
PMID: 10436842
Journal: Oncogene. 1999 Jul 1;18(26):3810-20.
Title: Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus.
Author: Robertson, K D|Jones, P A
PMID: 10445844
Journal: Cancer Gene Ther. 1999 Sep-Oct;6(5):428-36.
Title: Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells.
Author: Cascallo, M|Mercade, E|Capella, G|Lluis, F|Fillat, C|Gomez-Foix, A M|Mazo, A
PMID: 10505853
Journal: Int J Cancer. 1999 Nov 12;83(4):441-8.
Title: Characterization of ligurian melanoma families and risk of occurrence of other neoplasia.
Author: Ghiorzo, P|Ciotti, P|Mantelli, M|Heouaine, A|Queirolo, P|Rainero, M L|Ferrari, C|Santi, P L|De Marchi, R|Farris, A|Ajmar, F|Bruzzi, P|Bianchi-Scarra, G
PMID: 10508477
Journal: Cancer. 1999 Dec 1;86(11 Suppl):2464-77.
Title: The genetics of hereditary melanoma and nevi. 1998 update.
Author: Greene, M H
PMID: 10630172
Journal: Clin Cancer Res. 1999 Dec;5(12):4182-5.
Title: P16INK4a expression adenovirus vector to suppress pancreas cancer cell proliferation.
Author: Kobayashi, S|Shirasawa, H|Sashiyama, H|Kawahira, H|Kaneko, K|Asano, T|Ochiai, T
PMID: 10632358
Journal: Curr Opin Gastroenterol. 1999 Sep;15(5):404-9.
Title: Molecular genetics and related developments in pancreatic cancer.
Author: Hruban, R H|Goggins, M|Kern, S E
PMID: 17023981
Journal: Cancer Treat Rev. 2000 Feb;26(1):29-52.
Title: Molecular biology of pancreatic cancer; oncogenes, tumour suppressor genes, growth factors, and their receptors from a clinical perspective.
Author: Sakorafas, G H|Tsiotou, A G|Tsiotos, G G
PMID: 10660490
Journal: Cancer Res. 2000 Jan 15;60(2):409-16.
Title: Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations.
Author: Lal, G|Liu, G|Schmocker, B|Kaurah, P|Ozcelik, H|Narod, S A|Redston, M|Gallinger, S
PMID: 10667595
Journal: Blood. 2000 Mar 1;95(5):1869-71.
Title: Germline CDKN2A mutation implicated in predisposition to multiple myeloma.
Author: Dilworth, D|Liu, L|Stewart, A K|Berenson, J R|Lassam, N|Hogg, D
PMID: 10688850
Journal: Genes Chromosomes Cancer. 2000 Apr;27(4):358-61.
Title: Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations.
Author: Lal, G|Liu, L|Hogg, D|Lassam, N J|Redston, M S|Gallinger, S
PMID: 10719365
Journal: Nihon Geka Gakkai Zasshi. 2000 Feb;101(2):233-6.
Title: [General rules for the study of pancreatic cancer by molecular biological aspect].
Author: Omata, M|Tada, M
PMID: 10734643
Journal: Cancer Res. 2000 Apr 1;60(7):1835-9.
Title: Hypermethylation of multiple genes in pancreatic adenocarcinoma.
Author: Ueki, T|Toyota, M|Sohn, T|Yeo, C J|Issa, J P|Hruban, R H|Goggins, M
PMID: 10766168
Journal: J Surg Res. 2000 May 1;90(1):39-44.
Title: Pancreatic cancer cell proliferation is phosphatidylinositol 3-kinase dependent.
Author: Perugini, R A|McDade, T P|Vittimberga, F J Jr|Callery, M P
PMID: 10781373
Journal: J Natl Cancer Inst. 2000 Jun 21;92(12):1006-10.
Title: Genotype-phenotype relationships in U.S. melanoma-prone families with CDKN2A and CDK4 mutations.
Author: Goldstein, A M|Struewing, J P|Chidambaram, A|Fraser, M C|Tucker, M A
PMID: 10861313
Journal: Am J Pathol. 2000 Jul;157(1):83-92.
Title: Molecular analysis of microdissected tumors and preneoplastic intraductal lesions in pancreatic carcinoma.
Author: Heinmoller, E|Dietmaier, W|Zirngibl, H|Heinmoller, P|Scaringe, W|Jauch, K W|Hofstadter, F|Ruschoff, J
PMID: 10880379
Journal: J Natl Cancer Inst. 2000 Aug 2;92(15):1260-6.
Title: High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families.
Author: Borg, A|Sandberg, T|Nilsson, K|Johannsson, O|Klinker, M|Masback, A|Westerdahl, J|Olsson, H|Ingvar, C
PMID: 10922411
Journal: Appl Immunohistochem Mol Morphol. 2000 Mar;8(1):71-9.
Title: Immunohistochemical p16INK4a analysis of archival tumors with deletion, hypermethylation, or mutation of the CDKN2/MTS1 gene. A comparison of four commercial antibodies.
Author: Geradts, J|Hruban, R H|Schutte, M|Kern, S E|Maynard, R
PMID: 10937052
Journal: Am J Gastroenterol. 2000 Aug;95(8):2080-5.
Title: Association of poor prognosis with loss of 12q, 17p, and 18q, and concordant loss of 6q/17p and 12q/18q in human pancreatic ductal adenocarcinoma.
Author: Yatsuoka, T|Sunamura, M|Furukawa, T|Fukushige, S|Yokoyama, T|Inoue, H|Shibuya, K|Takeda, K|Matsuno, S|Horii, A
PMID: 10950061
Journal: Int J Cancer. 2000 Sep 15;87(6):809-11.
Title: Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden).
Author: Vasen, H F|Gruis, N A|Frants, R R|van Der Velden, P A|Hille, E T|Bergman, W
PMID: 10956390
Journal: Cancer Lett. 2000 Oct 31;159(2):151-8.
Title: Inhibition of pRb phosphorylation and cell cycle progression by an antennapedia-p16(INK4A) fusion peptide in pancreatic cancer cells.
Author: Fujimoto, K|Hosotani, R|Miyamoto, Y|Doi, R|Koshiba, T|Otaka, A|Fujii, N|Beauchamp, R D|Imamura, M
PMID: 10996726
Journal: Hum Mutat. 2000 Nov;16(5):447-8.
Title: A novel germline mutation, P48T, in the CDKN2A/p16 gene in a patient with pancreatic carcinoma.
Author: Moore, P S|Zamboni, G|Falconi, M|Bassi, C|Scarpa, A
PMID: 11058911
Journal: Pancreas. 2000 Nov;21(4):369-75.
Title: Multiple primary tumors as an indicator for p16INK4a germline mutations in pancreatic cancer patients?
Author: Gerdes, B|Bartsch, D K|Ramaswamy, A|Kersting, M|Wild, A|Schuermann, M|Frey, M|Rothmund, M
PMID: 11075991
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2000 Dec;17(6):399-403.
Title: [Study on the relationship of alteration and expression of p16 gene to pancreatic carcinoma].
Author: Zhou, J|Yang, D|Zhang, L|Wang, J|Yao, Q|Su, Z|Fan, Y
PMID: 11110976
Journal: Gastroenterology. 2000 Dec;119(6):1756-60.
Title: Genetic counseling and testing for germline p16 mutations in two pancreatic cancer-prone families.
Author: Lynch, H T|Brand, R E|Lynch, J F|Fusaro, R M|Smyrk, T C|Goggins, M|Kern, S E
PMID: 11113097
Journal: Cell Biochem Biophys. 2000;33(2):189-97.
Title: The physiology of p16(INK4A)-mediated G1 proliferative arrest.
Author: Shapiro, G I|Edwards, C D|Rollins, B J
PMID: 11325039
Journal: Zhonghua Wai Ke Za Zhi. 2000 Jun;38(6):457-9.
Title: [The growth inhibitory effects by transfection of p16 gene on human pancreatic cancer cell line].
Author: Zhang, J|Wang, M|He, S|Liu, Y|Zhang, B
PMID: 11832084
Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2000 Oct;22(5):491-3.
Title: [Alterations of the p16 gene for the carcinogenesis in pancreas].
Author: Wang, C|Lu, X
PMID: 12903437
Journal: Curr Opin Gastroenterol. 2000 Sep;16(5):419-25.
Title: Molecular genetics of ductal pancreatic neoplasia.
Author: Su, G H|Kern, S E
PMID: 17031113
Journal: Oncol Rep. 2001 Jan-Feb;8(1):89-92.
Title: Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines.
Author: Sun, C|Yamato, T|Furukawa, T|Ohnishi, Y|Kijima, H|Horii, A
PMID: 11115575
Journal: Genes Dev. 2001 Feb 1;15(3):286-93.
Title: A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease.
Author: Wagner, M|Greten, F R|Weber, C K|Koschnick, S|Mattfeldt, T|Deppert, W|Kern, H|Adler, G|Schmid, R M
PMID: 11159909
Journal: Br J Cancer. 2001 Jan;84(2):253-62.
Title: Pancreatic tumours: molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumorigenesis.
Author: Moore, P S|Orlandini, S|Zamboni, G|Capelli, P|Rigaud, G|Falconi, M|Bassi, C|Lemoine, N R|Scarpa, A
PMID: 11161385
Journal: Int J Cancer. 2001 Feb 1;91(3):350-8.
Title: Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping.
Author: Sirivatanauksorn, V|Sirivatanauksorn, Y|Gorman, P A|Davidson, J M|Sheer, D|Moore, P S|Scarpa, A|Edwards, P A|Lemoine, N R
PMID: 11169959
Journal: Virchows Arch. 2001 Feb;438(2):154-8.
Title: Successful xenografting of cryopreserved primary pancreatic cancers.
Author: Sorio, C|Bonora, A|Orlandini, S|Moore, P S|Capelli, P|Cristofori, P|Dal Negro, G|Marchiori, P|Gaviraghi, G|Falconi, M|Pederzoli, P|Zamboni, G|Scarpa, A
PMID: 11253117
Journal: Curr Gastroenterol Rep. 2001 Apr;3(2):121-8.
Title: Update on familial pancreatic cancer.
Author: Lynch, H T|Brand, R E|Deters, C A|Fusaro, R M
PMID: 11276379
Journal: Surgery. 2001 Apr;129(4):490-7.
Title: p16(INK4a) alterations in chronic pancreatitis-indicator for high-risk lesions for pancreatic cancer.
Author: Gerdes, B|Ramaswamy, A|Kersting, M|Ernst, M|Lang, S|Schuermann, M|Wild, A|Bartsch, D K
PMID: 11283541
Journal: Cancer Invest. 2001;19(1):65-75.
Title: The role of genetic factors in the etiology of pancreatic adenocarcinoma: an update.
Author: Chappuis, P O|Ghadirian, P|Foulkes, W D
PMID: 11291558
Journal: Gene Ther. 2001 Feb;8(3):199-208.
Title: Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo.
Author: Ghaneh, P|Greenhalf, W|Humphreys, M|Wilson, D|Zumstein, L|Lemoine, N R|Neoptolemos, J P
PMID: 11313791
Journal: Langenbecks Arch Surg. 2001 Apr;386(3):163-71.
Title: Carcinogenesis of cancer of the papilla and ampulla: pathophysiological facts and molecular biological mechanisms.
Author: Esposito, I|Friess, H|Buchler, M W
PMID: 11382316
Journal: Dig Dis. 2001;19(1):76-84.
Title: Prevention of pancreatic cancer and strategies for management of familial pancreatic cancer.
Author: Hruban, R H|Canto, M I|Yeo, C J
PMID: 11385254
Journal: Cancer Res. 2001 Aug 1;61(15):5905-10.
Title: Tumor suppressor genes in the 9p21 gene cluster are selective targets of inactivation in neuroendocrine gastroenteropancreatic tumors.
Author: Lubomierski, N|Kersting, M|Bert, T|Muench, K|Wulbrand, U|Schuermann, M|Bartsch, D|Simon, B
PMID: 11479232
Journal: Hepatogastroenterology. 2001 Jul-Aug;48(40):933-8.
Title: Molecular diagnosis of pancreatic cancer.
Author: Inoue, S|Tezel, E|Nakao, A
PMID: 11490843
Journal: BioDrugs. 2001;15(7):439-52.
Title: Molecular biology of pancreatic cancer: potential clinical implications.
Author: Sakorafas, G H|Tsiotos, G G
PMID: 11520255
Journal: Cancer J. 2001 Jul-Aug;7(4):251-8.
Title: Molecular pathology of pancreatic cancer.
Author: Hruban, R H|Iacobuzio-Donahue, C|Wilentz, R E|Goggins, M|Kern, S E
PMID: 11561601
Journal: Cancer Gene Ther. 2001 Oct;8(10):740-50.
Title: Adenovirus-mediated wt-p16 reintroduction induces cell cycle arrest or apoptosis in pancreatic cancer.
Author: Calbo, J|Marotta, M|Cascallo, M|Roig, J M|Gelpi, J L|Fueyo, J|Mazo, A
PMID: 11687897
Journal: Mod Pathol. 2001 Nov;14(11):1162-8.
Title: Immunohistochemical [corrected] detection of the alternate INK4a-encoded tumor suppressor protein p14(ARF) in archival human cancers and cell lines using commercial antibodies: correlation with p16(INK4a) expression.
Author: Geradts, J|Wilentz, R E|Roberts, H
PMID: 11706079
Journal: Gene. 2001 Oct 31;278(1-2):235-43.
Title: Identification and sequencing of the Syrian Golden hamster (Mesocricetus auratus) p16(INK4a) and p15(INK4b) cDNAs and their homozygous gene deletion in cheek pouch and pancreatic tumor cells.
Author: Muscarella, P|Knobloch, T J|Ulrich, A B|Casto, B C|Moniaux, N|Wittel, U A|Melvin, W S|Pour, P M|Song, H|Gold, B|Batra, S K|Weghorst, C M
PMID: 11707341
Journal: Virchows Arch. 2001 Dec;439(6):798-802.
Title: Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Author: Moore, P S|Sipos, B|Orlandini, S|Sorio, C|Real, F X|Lemoine, N R|Gress, T|Bassi, C|Kloppel, G|Kalthoff, H|Ungefroren, H|Lohr, M|Scarpa, A
PMID: 11787853
Journal: Pancreatology. 2001;1(4):363-8.
Title: TGF alpha transgenic mice. A model of pancreatic cancer development.
Author: Greten, F R|Wagner, M|Weber, C K|Zechner, U|Adler, G|Schmid, R M
PMID: 12120215
Journal: Pancreatology. 2001;1(5):466-71.
Title: Hereditary pancreatic cancer.
Author: Lynch, H T|Brand, R E|Deters, C A|Shaw, T G|Lynch, J F
PMID: 12120226
Journal: Pancreatology. 2001;1(5):510-6.
Title: Update of familial pancreatic cancer in Germany.
Author: Bartsch, D K|Sina-Frey, M|Ziegler, A|Hahn, S A|Przypadlo, E|Kress, R|Gerdes, B|Rieder, H
PMID: 12120230
Journal: Pancreatology. 2001;1(6):571-5.
Title: Pancreatic cancer genetics.
Author: Efthimiou, E|Crnogorac-Jurcevic, T|Lemoine, N R
PMID: 12120238
Journal: Asian Pac J Cancer Prev. 2001;2(4):271-280.
Title: An Epidemiological Overview of Environmental and Genetic Risk Factors of Pancreatic Cancer.
Author: Lin, Yingsong|Tamakoshi, Akiko|Kawamura, Takashi|Inaba, Yutaka|Kikuchi, Shogo|Motohashi, Yutaka|Kurosawa, Michiko|Ohno, Yoshiyuki
PMID: 12718618
Journal: Methods Mol Med. 2001;61:109-22.
Title: Genetic Testing in Familial Melanoma : Epidemiologic/Genetic Assessment of Risks and Role of CDKN2A Analysis.
Author: Hogg, D|Liu, L|Lassam, N
PMID: 22323255
Journal: Ann Surg. 2002 Jan;235(1):51-9.
Title: p16INK4a is a prognostic marker in resected ductal pancreatic cancer: an analysis of p16INK4a, p53, MDM2, an Rb.
Author: Gerdes, Berthold|Ramaswamy, Annette|Ziegler, Andreas|Lang, Sven A|Kersting, Michael|Baumann, Renate|Wild, Anja|Moll, Roland|Rothmund, Matthias|Bartsch, Detlef K
PMID: 11753042
Journal: Mol Cell Biol. 2002 Jan;22(2):635-43.
Title: Obligate roles for p16(Ink4a) and p19(Arf)-p53 in the suppression of murine pancreatic neoplasia.
Author: Bardeesy, Nabeel|Morgan, Jeffrey|Sinha, Manisha|Signoretti, Sabina|Srivastava, Shefali|Loda, Massimo|Merlino, Glenn|DePinho, Ronald A
PMID: 11756558
Journal: J Natl Cancer Inst. 2002 Jan 16;94(2):129-42.
Title: Overexpression of pRB in human pancreatic carcinoma cells: function in chemotherapy-induced apoptosis.
Author: Plath, Thomas|Peters, Michael|Detjen, Katharina|Welzel, Martina|von Marschall, Zofia|Radke, Cornelia|Wiedenmann, Bertram|Rosewicz, Stefan
PMID: 11792751
Journal: Am J Med Genet. 2002 Jan 22;107(3):214-21.
Title: High prevalence of the G101W germline mutation in the CDKN2A (P16(ink4a)) gene in 62 Italian malignant melanoma families.
Author: Mantelli, Michela|Barile, Monica|Ciotti, Paola|Ghiorzo, Paola|Lantieri, Francesca|Pastorino, Lorenza|Catricala, Caterina|Torre, Gabriella Della|Folco, Ugo|Grammatico, Paola|Padovani, Laura|Pasini, Barbara|Rovini, Dario|Queirolo, Paola|Rainero, Maria Luisa
PMID: 11807902
Journal: Cancer. 2002 Jan 1;94(1):84-96.
Title: Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome.
Author: Lynch, Henry T|Brand, Randall E|Hogg, David|Deters, Carolyn A|Fusaro, Ramon M|Lynch, Jane F|Liu, Ling|Knezetic, Joseph|Lassam, Norman J|Goggins, Michael|Kern, Scott
PMID: 11815963
Journal: Clin Cancer Res. 2002 Apr;8(4):1271-6.
Title: Trojan p16 peptide suppresses pancreatic cancer growth and prolongs survival in mice.
Author: Hosotani, Ryo|Miyamoto, Yoshiharu|Fujimoto, Koji|Doi, Ryuichiro|Otaka, Akira|Fujii, Nobutaka|Imamura, Masayuki
PMID: 11948142
Journal: Mod Pathol. 2002 Apr;15(4):441-7.
Title: Direct correlation between proliferative activity and dysplasia in pancreatic intraepithelial neoplasia (PanIN): additional evidence for a recently proposed model of progression.
Author: Klein, Walter M|Hruban, Ralph H|Klein-Szanto, Andres J P|Wilentz, Robb E
PMID: 11950919
Journal: Am J Pathol. 2002 May;160(5):1573-81.
Title: Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma.
Author: Fukushima, Noriyoshi|Sato, Norihiro|Ueki, Takashi|Rosty, Christophe|Walter, Kimberly M|Wilentz, Robb E|Yeo, Charles J|Hruban, Ralph H|Goggins, Michael
PMID: 12000709
Journal: Gut. 2002 Jun;50(6):861-8.
Title: Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma.
Author: Biankin, A V|Biankin, S A|Kench, J G|Morey, A L|Lee, C-S|Head, D R|Eckstein, R P|Hugh, T B|Henshall, S M|Sutherland, R L
PMID: 12010891
Journal: J Hepatobiliary Pancreat Surg. 2002;9(1):1-11.
Title: Molecular prognostic markers in pancreatic cancer.
Author: Ghaneh, Paula|Kawesha, Anthony|Evans, James D|Neoptolemos, John P
PMID: 12021893
Journal: J Hepatobiliary Pancreat Surg. 2002;9(1):12-31.
Title: Hereditary factors in pancreatic cancer.
Author: Lynch, Henry T|Brand, Randall E|Lynch, Jane F|Fusaro, Ramon M|Kern, Scott E
PMID: 12021894
Journal: Cell Tissue Res. 2002 May;308(2):205-14. Epub 2002 Apr 11.
Title: Establishment and characterization of four human pancreatic carcinoma cell lines. Genetic alterations in the TGFBR2 gene but not in the MADH4 gene.
Author: Ku, Ja-Lok|Yoon, Kyong-Ah|Kim, Woo-Ho|Jang, Young|Suh, Kyung-Suk|Kim, Sun-Whe|Park, Yong-Hyun|Park, Jae-Gahb
PMID: 12037578
Journal: Hematol Oncol Clin North Am. 2002 Feb;16(1):17-35, v.
Title: Molecular pathogenesis of pancreatic cancer.
Author: Hilgers, Werner|Rosty, Christophe|Hahn, Stephan A
PMID: 12063826
Journal: Best Pract Res Clin Gastroenterol. 2002 Jun;16(3):421-33.
Title: Genetic basis of pancreatic cancer.
Author: Schmid, Roland M
PMID: 12079267
Journal: Nihon Geka Gakkai Zasshi. 2002 Jun;103(6):476-81.
Title: [Genetics of pancreatic cancer: recent advances in molecular diagnosis].
Author: Hayashi, Naoko|Egami, Hiroshi|Ogawa, Michio
PMID: 12094699
Journal: Onkologie. 2002 Jun;25(3):262-6.
Title: German national case collection of familial pancreatic cancer - clinical-genetic analysis of the first 21 families.
Author: Rieder, H|Sina-Frey, M|Ziegler, A|Hahn, S A|Przypadlo, E|Kress, R|Gerdes, B|Colombo Benkmann, M|Eberl, T|Grutzmann, R|Lorken, M|Schmidt, J|Bartsch, D K
PMID: 12119461
Journal: Pancreatology. 2002;2(1):17-25.
Title: Frequent deletions of tumor suppressor genes in pure pancreatic juice from patients with tumoral or nontumoral pancreatic diseases.
Author: Costentin, Lydie|Pages, Philippe|Bouisson, Michele|Berthelemy, Philippe|Buscail, Louis|Escourrou, Jean|Pradayrol, Lucien|Vaysse, Nicole
PMID: 12120000
Journal: J Clin Oncol. 2002 Dec 1;20(23):4531-42.
Title: DPC4/Smad4 expression and outcome in pancreatic ductal adenocarcinoma.
Author: Biankin, Andrew V|Morey, Adrienne L|Lee, C-Soon|Kench, James G|Biankin, Sandra A|Hook, Henry C|Head, Darren R|Hugh, Thomas B|Sutherland, Robert L|Henshall, Susan M
PMID: 12454109
Journal: Ann Surg. 2002 Dec;236(6):730-7.
Title: CDKN2A germline mutations in familial pancreatic cancer.
Author: Bartsch, Detlef K|Sina-Frey, Mercedes|Lang, Sven|Wild, Anja|Gerdes, Berthold|Barth, Peter|Kress, Ralf|Grutzmann, Robert|Colombo-Benkmann, Mario|Ziegler, Andreas|Hahn, Stephan A|Rothmund, Matthias|Rieder, Harald
PMID: 12454511
Journal: Melanoma Res. 2002 Dec;12(6):559-63.
Title: The CDKN2A tumour suppressor gene: no mutations detected in patients with melanoma and additional unrelated cancers.
Author: Alao, J P|Mohammed, M Q|Retsas, S
PMID: 12459645
Journal: Ai Zheng. 2002 Feb;21(2):132-7.
Title: [Expression of DPC4/Smad4, p21wafI, and p16 in human pancreatic cancer].
Author: Gu, Li-jun|Chen, Jie|Lu, Zhao-hui|Li, Li|Zhou, Wei-xun|Luo, Yu-feng
PMID: 12479060
Journal: Ann Pathol. 2002 Oct;22(5):349-55.
Title: [Molecular pathways of pancreatic carcinogenesis].
Author: Torrisani, Jerome|Buscail, Louis
PMID: 12483152
Journal: Oncology (Williston Park). 2002 Dec;16(12):1615-22, 1631-2; discussion 1632-3,
Title: Pancreatic cancer: epidemiology, genetics, and approaches to screening.
Author: Konner, Jason|O'Reilly, Eileen
PMID: 12520639
Journal: Int J Gastrointest Cancer. 2002;31(1-3):191-7.
Title: Minute invasive ductal carcinoma of the residual pancreas after distal pancreatectomy for intraductal papillary-mucinous tumor.
Author: Moriya, Toshiyuki|Kimura, Wataru|Sakurai, Fumiaki|Semba, Shuho|Ozawa, Koichiro|Hirai, Ichiro|Fuse, Akira
PMID: 12622431
Journal: Oncol Rep. 2003 Jan-Feb;10(1):21-5.
Title: Differential roles of alterations of p53, p16, and SMAD4 expression in the progression of intraductal papillary-mucinous tumors of the pancreas.
Author: Sasaki, Shigeru|Yamamoto, Hiroyuki|Kaneto, Hiroyuki|Ozeki, Itaru|Adachi, Yasuyo|Takagi, Hideyasu|Matsumoto, Takeshi|Itoh, Hideto|Nagakawa, Tatsuya|Miyakawa, Hiroyuki|Muraoka, Shunji|Fujinaga, Akira|Suga, Toshihiro|Satoh, Masaaki|Itoh, Fumio|Endo, Takao|Im
PMID: 12469138
Journal: Pancreas. 2003 Jan;26(1):42-8.
Title: Tumor-suppressing pathways in cystic pancreatic tumors.
Author: Gerdes, Berthold|Wild, Anja|Wittenberg, Judith|Barth, Peter|Ramaswamy, Annette|Kersting, Michael|Luttges, Jutta|Kloppel, Gunter|Bartsch, Detlef K
PMID: 12499916
Journal: Mol Cancer. 2003 Jan 7;2:7.
Title: Genetic abnormalities in pancreatic cancer.
Author: Moore, Patrick S|Beghelli, Stefania|Zamboni, Giuseppe|Scarpa, Aldo
PMID: 12537585
Journal: Mol Cancer. 2003 Jan 22;2:15.
Title: Genetic alterations in pancreatic carcinoma.
Author: Schneider, Gunter|Schmid, Roland M
PMID: 12605716
Journal: Br J Cancer. 2003 Jan 27;88(2):217-22.
Title: Methylation status of p14ARF and p16INK4a as detected in pancreatic secretions.
Author: Klump, B|Hsieh, C J|Nehls, O|Dette, S|Holzmann, K|Kiesslich, R|Jung, M|Sinn, U|Ortner, M|Porschen, R|Gregor, M
PMID: 12610506
Journal: Chirurg. 2003 Mar;74(3):165-70.
Title: [Pancreatic carcinogenesis. Clinical implications].
Author: Schneider, G|Lersch, C|Schmid, R M
PMID: 12647072
Journal: Virchows Arch. 2003 May;442(5):444-52.
Title: A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform.
Author: Sipos, Bence|Moser, Simone|Kalthoff, Holger|Torok, Virag|Lohr, Matthias|Kloppel, Gunter
PMID: 12692724
Journal: Biochem Biophys Res Commun. 2003 May 2;304(2):241-7.
Title: Expression and characterization of Syrian golden hamster p16, a homologue of human tumor suppressor p16 INK4A.
Author: Li, Junan|Qin, Dongyan|Knobloch, Thomas J|Tsai, Ming-Daw|Weghorst, Christopher M|Melvin, W Scott|Muscarella, Peter
PMID: 12711305
Journal: Cancer Res. 2003 May 1;63(9):2005-9.
Title: The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice.
Author: Brembeck, Felix H|Schreiber, Franz S|Deramaudt, Therese B|Craig, Linden|Rhoades, Ben|Swain, Gary|Grippo, Paul|Stoffers, Doris A|Silberg, Debra G|Rustgi, Anil K
PMID: 12727809
Journal: Hepatogastroenterology. 2003 Mar-Apr;50(50):541-4.
Title: P53 mutation but not p16/MTS1 mutation occurs in intraductal papillary mucinous tumors of the pancreas.
Author: Mueller, J|Gansauge, S|Mattfeldt, T
PMID: 12749268
Journal: Oncogene. 2003 Jun 12;22(24):3806-12.
Title: Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.
Author: Dammann, Reinhard|Schagdarsurengin, Undraga|Liu, Limin|Otto, Noreen|Gimm, Oliver|Dralle, Henning|Boehm, Bernhard O|Pfeifer, Gerd P|Hoang-Vu, Cuong
PMID: 12802288
Journal: J Natl Cancer Inst. 2003 Jul 2;95(13):948-60.
Title: Etiology of pancreatic cancer, with a hypothesis concerning the role of N-nitroso compounds and excess gastric acidity.
Author: Risch, Harvey A
PMID: 12837831
Journal: Zhonghua Yi Xue Za Zhi. 2003 May 25;83(10):868-71.
Title: [The relationship between tumor suppressor genes p14ARF and p53 expression and biological behavior of pancreatic carcinoma].
Author: Chen, Xiao-lei|Zhang, Qun-hua|Ni, Quan-xing
PMID: 12895341
Journal: J Gastroenterol. 2003;38(7):663-71.
Title: Abnormalities of tumor suppressor gene p16 in pancreatic carcinoma: immunohistochemical and genetic findings compared with clinicopathological parameters.
Author: Ohtsubo, Koushiro|Watanabe, Hiroyuki|Yamaguchi, Yasushi|Hu, Yu-Xin|Motoo, Yoshiharu|Okai, Takashi|Sawabu, Norio
PMID: 12898359
Journal: Cancer. 2003 Aug 15;98(4):798-804.
Title: Characterization of the neoplastic phenotype in the familial atypical multiple-mole melanoma-pancreatic carcinoma syndrome.
Author: Rulyak, Stephen J|Brentnall, Teresa A|Lynch, Henry T|Austin, Melissa A
PMID: 12910525
Journal: Pathol Res Pract. 2003;199(6):363-71.
Title: Laser microdissection of small tissue samples--application to chronic pancreatitis tissues.
Author: Heinmoller, Ernst|Bockholt, Anke|Werther, Meike|Ziemer, Maria|Muller, Annegret|Ghadimi, B Michael|Ruschoff, Josef
PMID: 12924436
Journal: Arch Dermatol. 2003 Aug;139(8):1019-25.
Title: Pancreatic carcinoma surveillance in patients with familial melanoma.
Author: Parker, Jana Foley|Florell, Scott R|Alexander, April|DiSario, James A|Shami, Paul J|Leachman, Sancy A
PMID: 12925390
Journal: Chin Med J (Engl). 2003 Aug;116(8):1150-5.
Title: p14ARF upregulation of p53 and enhanced effects of 5-fluorouracil in pancreatic cancer.
Author: Zhang, Qunhua|Ni, Quanxing|Gan, Jun|Shen, Zhaozhong|Luo, Jianmin|Jin, Chen|Zhang, Niu|Zhang, Yanling
PMID: 12935400
Journal: Am J Surg. 2003 Sep;186(3):279-86.
Title: The genetics of pancreatic cancer.
Author: Cowgill, Sarah M|Muscarella, Peter
PMID: 12946833
Journal: Mod Pathol. 2003 Sep;16(9):902-12.
Title: Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray.
Author: Maitra, Anirban|Adsay, N Volkan|Argani, Pedram|Iacobuzio-Donahue, Christine|De Marzo, Angelo|Cameron, John L|Yeo, Charles J|Hruban, Ralph H
PMID: 13679454
Journal: Ann Surg. 2003 Sep;238(3):423-31; discussion 431-2.
Title: Aberrant hypermethylation of tumor suppressor genes in pancreatic endocrine neoplasms.
Author: House, Michael G|Herman, James G|Guo, Ming Zhou|Hooker, Craig M|Schulick, Richard D|Lillemoe, Keith D|Cameron, John L|Hruban, Ralph H|Maitra, Anirban|Yeo, Charles J
PMID: 14501508
Journal: Ther Umsch. 2003 Aug;60(8):469-72.
Title: [Genetic counseling and DNA testing in patients with increased risks for malignant melanoma].
Author: Itin, P H|Fistarol, S K
PMID: 14502854
Journal: Clin Cancer Res. 2003 Sep 1;9(10 Pt 1):3598-605.
Title: Pancreatic carcinoma in carriers of a specific 19 base pair deletion of CDKN2A/p16 (p16-leiden).
Author: de vos tot Nederveen Cappel, Wouter H|Offerhaus, G Johan A|van Puijenbroek, Marjo|Caspers, Eric|Gruis, Nelleke A|De Snoo, Femke A|Lamers, Cornelis B H W|Griffioen, Gerrit|Bergman, Wilma|Vasen, Hans F A|Morreau, Hans
PMID: 14506146
Journal: Genes Chromosomes Cancer. 2003 Nov;38(3):240-8.
Title: Pattern of secondary genomic changes in pancreatic tumors of Tgf alpha/Trp53+/- transgenic mice.
Author: Schreiner, Bettina|Baur, Dorothee M|Fingerle, Alexander A|Zechner, Ulrich|Greten, Florian R|Adler, Guido|Sipos, Bence|Kloppel, Gunter|Hameister, Horst|Schmid, Roland M
PMID: 14506698
Journal: J Surg Res. 2003 Nov;115(1):41-7.
Title: Somatostatin receptor gene transfer inhibits established pancreatic cancer xenografts.
Author: Celinski, Scott A|Fisher, William E|Amaya, Felipe|Wu, Yuan Qing|Yao, Q|Youker, Keith A|Li, Min
PMID: 14572771
Journal: Cancer. 2003 Nov 1;98(9):1947-57.
Title: Familial sarcoma: challenging pedigrees.
Author: Lynch, Henry T|Deters, Carolyn A|Hogg, David|Lynch, Jane F|Kinarsky, Yulia|Gatalica, Zoran
PMID: 14584079
Journal: Am J Surg Pathol. 2003 Dec;27(12):1495-501.
Title: p16 Inactivation in pancreatic intraepithelial neoplasias (PanINs) arising in patients with chronic pancreatitis.
Author: Rosty, Christophe|Geradts, Joseph|Sato, Norihiro|Wilentz, Robb E|Roberts, Helen|Sohn, Taylor|Cameron, John L|Yeo, Charles J|Hruban, Ralph H|Goggins, Michael
PMID: 14657708
Journal: Electrophoresis. 2003 Dec;24(24):4291-303.
Title: Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2'-deoxycytidine.
Author: Cecconi, Daniela|Astner, Hubert|Donadelli, Massimo|Palmieri, Marta|Missiaglia, Edoardo|Hamdan, Mahmoud|Scarpa, Aldo|Righetti, Pier Giorgio
PMID: 14679576
Journal: Genes Dev. 2003 Dec 15;17(24):3127-38. Epub 2003 Dec 17.
Title: The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer.
Author: Lewis, Brian C|Klimstra, David S|Varmus, Harold E
PMID: 14681205
Journal: Genes Dev. 2003 Dec 15;17(24):3112-26.
Title: Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.
Author: Aguirre, Andrew J|Bardeesy, Nabeel|Sinha, Manisha|Lopez, Lyle|Tuveson, David A|Horner, James|Redston, Mark S|DePinho, Ronald A
PMID: 14681207
Journal: Scand J Gastroenterol Suppl. 2003;(239):94-9.
Title: Surveillance for familial pancreatic cancer.
Author: de Vos tot Nederveen Cappel, W H|Lagendijk, M A C|Lamers, C B H W|Morreau, H|Vasen, H F A
PMID: 14743890
Journal: Carcinogenesis. 2004 Feb;25(2):263-8. Epub 2003 Nov 6.
Title: Frequent p16INK4A/CDKN2A alterations in chemically induced Syrian golden hamster pancreatic tumors.
Author: Li, Junan|Weghorst, Christopher M|Tsutsumi, Masahiro|Poi, Ming J|Knobloch, Thomas J|Casto, Bruce C|Melvin, W Scott|Tsai, Ming-Daw|Muscarella, Peter
PMID: 14604895
Journal: Ann Oncol. 2004 Jan;15(1):70-8.
Title: INK4/ARF germline alterations in pancreatic cancer patients.
Author: Ghiorzo, P|Pastorino, L|Bonelli, L|Cusano, R|Nicora, A|Zupo, S|Queirolo, P|Sertoli, M|Pugliese, V|Bianchi-Scarra, G
PMID: 14679123
Journal: Br J Cancer. 2004 Jan 26;90(2):503-9.
Title: Germline mutations of the INK4a-ARF gene in patients with suspected genetic predisposition to melanoma.
Author: Soufir, N|Lacapere, J J|Bertrand, G|Matichard, E|Meziani, R|Mirebeau, D|Descamps, V|Gerard, B|Archimbaud, A|Ollivaud, L|Bouscarat, F|Baccard, M|Lanternier, G|Saiag, P|Lebbe, C|Basset-Seguin, N|Crickx, B|Cave, H|Grandchamp, B
PMID: 14735200
Journal: Laryngorhinootologie. 2004 Jan;83(1):55-60.
Title: [Biallelic inactivation of the p16-Gen in a metachronous triple carcinoma in the oropharyngeal region].
Author: Motsch, C|Giers, A|Boltze, C|Evert, M|Freigang, B|Roessner, A|Schneider-Stock, R
PMID: 14740307
Journal: Dermatol Surg. 2004 Feb;30(2 Pt 2):291-6.
Title: FAMMM syndrome: pathogenesis and management.
Author: Czajkowski, Rafal|Placek, Waldemar|Drewa, Gerard|Czajkowska, Aldona|Uchanska, Grazyna
PMID: 14871223
Journal: Virchows Arch. 2004 May;444(5):447-53.
Title: Microcystic tubulopapillary carcinoma of the pancreas: a new tumor entity?
Author: Esposito, Irene|Bauer, Andrea|Hoheisel, Jorg D|Kleeff, Jorg|Friess, Helmut|Bergmann, Frank|Rieker, Ralf J|Otto, Herwart F|Kloppel, Gunter|Penzel, Roland
PMID: 15014986
Journal: J Cancer Res Clin Oncol. 2004 Jun;130(6):339-45.
Title: Allelotype of ampulla of Vater cancer: highly frequent involvement of chromosome 11.
Author: Moore, Patrick S|Missiaglia, Edoardo|Beghelli, Stefania|Bragantini, Emma|Mina, Maria M|Zamboni, Giuseppe|Falconi, Massimo|Scarpa, Aldo
PMID: 15024645
Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004 Feb;26(1):79-82.
Title: [Recent advances in gene change of pancreatic cancer].
Author: Wang, Yu-yue|Cui, Quan-cai
PMID: 15052782
Journal: Cancer. 2004 May 1;100(9):1978-86.
Title: Characterization of FAMPAC, a newly identified human pancreatic carcinoma cell line with a hereditary background.
Author: Eisold, Sven|Ryschich, Eduard|Linnebacher, Michael|Giese, Thomas|Nauheimer, Dirk|Wild, Anja|Bartsch, Detlef K|Buchler, Markus W|Schmidt, Jan
PMID: 15112280
Journal: Zhonghua Bing Li Xue Za Zhi. 2004 Apr;33(2):130-4.
Title: [Expression of proteins in p53 (p14ARF-mdm2-p53-p21WAF/CIP1) pathway and their significance in exocrine pancreatic carcinoma].
Author: Yu, Guan-zhen|Zhu, Ming-hua|Ni, Can-rong|Li, Fang-mei|Zheng, Jian-ming|Gong, Zhi-jin
PMID: 15132849
Journal: J Gene Med. 2004 May;6(5):514-25.
Title: 5-Fluorouracil or gemcitabine combined with adenoviral-mediated reintroduction of p16INK4A greatly enhanced cytotoxicity in Panc-1 pancreatic adenocarcinoma cells.
Author: Halloran, Christopher M|Ghaneh, Paula|Shore, Susannah|Greenhalf, William|Zumstein, Lou|Wilson, Deborah|Neoptolemos, John P|Costello, Eithne
PMID: 15133762
Journal: Hum Mutat. 2004 Jun;23(6):630.
Title: Familial melanoma, pancreatic cancer and germline CDKN2A mutations.
Author: Goldstein, Alisa M
PMID: 15146471
Journal: Nihon Rinsho. 2004 May;62(5):889-93.
Title: [Alteration of the K-ras and p16/CDKN2 gene in endocrine pancreatic carcinomas].
Author: Shirahama, Shuya|Matsuyoshi, Junko|Yamamoto, Shigeki|Tsukada, Yutaka
PMID: 15148814
Journal: J Med Genet. 2004 Jun;41(6):421-4.
Title: Prospective risk of cancer in CDKN2A germline mutation carriers.
Author: Goldstein, A M|Struewing, J P|Fraser, M C|Smith, M W|Tucker, M A
PMID: 15173226
Journal: Am J Med Genet C Semin Med Genet. 2004 Aug 15;129C(1):5-22.
Title: Inherited predisposition to cancer: a historical overview.
Author: Lynch, Henry T|Shaw, Trudy G|Lynch, Jane F
PMID: 15264268
Journal: Cell Death Differ. 2004 Oct;11(10):1055-65.
Title: The fate of pancreatic tumor cell lines following p16 overexpression depends on the modulation of CDK2 activity.
Author: Calbo, J|Serna, C|Garriga, J|Grana, X|Mazo, A
PMID: 15309028
Journal: Biochem Biophys Res Commun. 2004 Sep 24;322(3):930-4.
Title: Restoration of protein synthesis in pancreatic cancer cells by trans-splicing ribozymes.
Author: Kastanos, Evdokia|Hjiantoniou, Eleni|Phylactou, Leonidas A
PMID: 15336553
Journal: Pancreas. 2004 Oct;29(3):193-203.
Title: Orthotopic transplantation models of pancreatic adenocarcinoma derived from cell lines and primary tumors and displaying varying metastatic activity.
Author: Loukopoulos, Panayiotis|Kanetaka, Kengo|Takamura, Masaaki|Shibata, Tatsuhiro|Sakamoto, Michiie|Hirohashi, Setsuo
PMID: 15367885
Journal: Clin Cancer Res. 2004 Oct 1;10(19):6598-605.
Title: Overexpression of G1-S cyclins and cyclin-dependent kinases during multistage human pancreatic duct cell carcinogenesis.
Author: Al-Aynati, Maamoun M|Radulovich, Nikolina|Ho, James|Tsao, Ming-Sound
PMID: 15475449
Journal: Fam Cancer. 2004;3(3-4):233-40.
Title: Familial pancreatic carcinoma in Jews.
Author: Lynch, Henry T|Deters, Carolyn A|Lynch, Jane F|Brand, Randall E
PMID: 15516847
Journal: Oncology. 2004;67(3-4):277-90.
Title: Expression profiles of a human pancreatic cancer cell line upon induction of apoptosis search for modulators in cancer therapy.
Author: Blasco, F|Penuelas, S|Cascallo, M|Hernandez, J L|Alemany, C|Masa, M|Calbo, J|Soler, M|Nicolas, M|Perez-Torras, S|Gomez, A|Tarrason, G|Noe, V|Mazo, A|Ciudad, C J|Piulats, J
PMID: 15557790
Journal: Dig Dis. 2004;22(3):235-8.
Title: Molecular analysis of pancreatic juice: a helpful tool to differentiate benign and malignant pancreatic tumors?
Author: Teich, Niels|Mossner, Joachim
PMID: 15753605
Journal: Langenbecks Arch Surg. 2005 Apr;390(2):94-103.
Title: Survival after surgical management of pancreatic adenocarcinoma: does curative and radical surgery truly exist?
Author: Smeenk, H G|Tran, T C K|Erdmann, J|van Eijck, C H J|Jeekel, J
PMID: 15578211
Journal: Oncogene. 2005 Jan 6;24(1):199-211.
Title: Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway.
Author: Missiaglia, Edoardo|Donadelli, Massimo|Palmieri, Marta|Crnogorac-Jurcevic, Tatjana|Scarpa, Aldo|Lemoine, Nicholas R
PMID: 15637593
Journal: Cancer Biol Ther. 2005 Jan;4(1):83-6. Epub 2005 Jan 15.
Title: Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: a potential new target for therapy.
Author: Hustinx, Steven R|Hruban, Ralph H|Leoni, Lorenzo M|Iacobuzio-Donahue, Christine|Cameron, John L|Yeo, Charles J|Brown, Priscilla N|Argani, Pedram|Ashfaq, Raheela|Fukushima, Noriyoshi|Goggins, Michael|Kern, Scott E|Maitra, Anirban
PMID: 15662124
Journal: Virchows Arch. 2005 Mar;446(3):239-45.
Title: Mucinous cystic carcinoma of the pancreas: a unique cell line and xenograft model of a preinvasive lesion.
Author: Sorio, Claudio|Capelli, Paola|Lissandrini, Daniele|Moore, Patrick S|Balzarini, Piera|Falconi, Massimo|Zamboni, Giuseppe|Scarpa, Aldo
PMID: 15688169
Journal: Cancer Res. 2005 Mar 15;65(6):2260-8.
Title: Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas.
Author: Vance, Keith W|Carreira, Suzanne|Brosch, Gerald|Goding, Colin R
PMID: 15781639
Journal: Hepatogastroenterology. 2005 Mar-Apr;52(62):398-403.
Title: MUC1 overexpression is the most reliable marker of invasive carcinoma in intraductal papillary-mucinous tumor (IPMT).
Author: Ueda, Michio|Miura, Yasuhiko|Kunihiro, Osamu|Ishikawa, Takashi|Ichikawa, Yasushi|Endo, Itaru|Sekido, Hitoshi|Togo, Shinji|Shimada, Hiroshi
PMID: 15816444
Journal: Mod Pathol. 2005 Aug;18(8):1034-42.
Title: Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas.
Author: Furukawa, Toru|Fujisaki, Rumi|Yoshida, Yoshitaro|Kanai, Naomi|Sunamura, Makoto|Abe, Tadayoshi|Takeda, Kazunori|Matsuno, Seiki|Horii, Akira
PMID: 15832194
Journal: Mod Pathol. 2005 Jul;18(7):959-63.
Title: Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion.
Author: Hustinx, Steven R|Leoni, Lorenzo M|Yeo, Charles J|Brown, Priscilla N|Goggins, Michael|Kern, Scott E|Hruban, Ralph H|Maitra, Anirban
PMID: 15832197
Journal: Cancer Genet Cytogenet. 2005 May;159(1):10-7.
Title: AURKA amplification, chromosome instability, and centrosome abnormality in human pancreatic carcinoma cells.
Author: Zhu, Jijiang|Abbruzzese, James L|Izzo, Julie|Hittelman, Walter N|Li, Donghui
PMID: 15860351
Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2005 Feb;30(1):7-10, 15.
Title: [Anti-tumor effect of pcDNA3. 1-Egr. 1p-p16 gene combined with radiotherapy in tumor-bearing nude mice].
Author: Ma, Hong-bing|Wang, Xi-jing|Hu, Hai-tao|Di, Zheng-li|Xia, Hui|Wang, Zheng|Li, Cheng|Han, Zhi-kai|Ma, Jie|Wu, Cong-mei
PMID: 15871178
Journal: Drugs Today (Barc). 2005 Mar;41(3):193-203.
Title: The genetics of susceptibility to cutaneous melanoma.
Author: Newton Bishop, Julia A|Bishop, D Timothy
PMID: 15883616
Journal: Genes Chromosomes Cancer. 2005 Sep;44(1):37-51.
Title: Analysis of genomic DNA alterations and mRNA expression patterns in a panel of human pancreatic cancer cell lines.
Author: Gysin, Stephan|Rickert, Paula|Kastury, Kumar|McMahon, Martin
PMID: 15929091
Journal: Gastroenterology. 2005 Jun;128(7):2124-30.
Title: Molecular analysis to detect pancreatic ductal adenocarcinoma in high-risk groups.
Author: Yan, Li|McFaul, Christopher|Howes, Nathan|Leslie, Jane|Lancaster, Gillian|Wong, Theresa|Threadgold, Jane|Evans, Jonathan|Gilmore, Ian|Smart, Howard|Lombard, Martin|Neoptolemos, John|Greenhalf, William
PMID: 15940643
Journal: Praxis (Bern 1994). 2005 May 18;94(20):811-7.
Title: [Chronic pancreatitis--pancreas cancer: influence of genetic factors].
Author: Keim, V
PMID: 15957615
Journal: Cancer Res. 2005 Jun 15;65(12):5045-53.
Title: In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis.
Author: Qian, Jiaying|Niu, Jiangong|Li, Ming|Chiao, Paul J|Tsao, Ming-Sound
PMID: 15958547
Journal: Biochem Biophys Res Commun. 2005 Aug 12;333(4):1249-53.
Title: Cloning of the hamster p16 gene 5' upstream region and its aberrant methylation patterns in pancreatic cancer.
Author: Hanaoka, Madoka|Shimizu, Kyoko|Shigemura, Mayumi|Kato, Ayumi|Fujii, Hiromasa|Honoki, Kanya|Tsujiuchi, Toshifumi
PMID: 15979573
Journal: BMC Gastroenterol. 2005 Jun 28;5:22.
Title: Alterations of tumor suppressor gene p16INK4a in pancreatic ductal carcinoma.
Author: Attri, Jyotika|Srinivasan, Radhika|Majumdar, Siddhartha|Radotra, Bishan Dass|Wig, Jaidev
PMID: 15985168
Journal: Cancer Genet Cytogenet. 2005 Aug;161(1):36-50.
Title: Genome-wide aberrations in pancreatic adenocarcinoma.
Author: Nowak, Norma J|Gaile, Daniel|Conroy, Jeffrey M|McQuaid, Devin|Cowell, John|Carter, Randy|Goggins, Michael G|Hruban, Ralph H|Maitra, Anirban
PMID: 16080956
Journal: Cancer Genet Cytogenet. 2005 Sep;161(2):140-5.
Title: Identification of oligodendroglioma specific chromosomal copy number changes in the glioblastoma MI-4 cell line by array-CGH and FISH analyses.
Author: Magnani, Ivana|Moroni, Ramona Frida|Roversi, Gaia|Beghini, Alessandro|Pfundt, Rolph|Schoenmakers, Eric F|Larizza, Lidia
PMID: 16102584
Journal: Yonsei Med J. 2005 Aug 31;46(4):519-25.
Title: Clinical significance of p16 protein expression loss and aberrant p53 protein expression in pancreatic cancer.
Author: Jeong, Joon|Park, Young Nyun|Park, Joon Seong|Yoon, Dong-Sup|Chi, Hoon Sang|Kim, Byong Ro
PMID: 16127777
Journal: Eur J Cancer. 2005 Oct;41(15):2213-36.
Title: Molecular prognostic markers in pancreatic cancer: a systematic review.
Author: Garcea, G|Neal, C P|Pattenden, C J|Steward, W P|Berry, D P
PMID: 16146690
Journal: Curr Treat Options Gastroenterol. 2005 Oct;8(5):365-75.
Title: Treatment of familial pancreatic cancer and its precursors.
Author: Hruban, Ralph H|Canto, Marcia I|Griffin, Constance|Kern, Scott E|Klein, Alison P|Laheru, Dan|Yeo, Charles J
PMID: 16162302
Journal: Semin Radiat Oncol. 2005 Oct;15(4):254-64.
Title: Ductal neoplasia of the pancreas: nosologic, clinicopathologic, and biologic aspects.
Author: Adsay, Nazmi Volkan|Basturk, Olca|Cheng, Jeanette D|Andea, Aleodor A
PMID: 16183479
Journal: Zhonghua Bing Li Xue Za Zhi. 2005 Jul;34(7):389-92.
Title: [Mucinous noncystic (colloid) adenocarcinoma of the pancreas].
Author: Zhu, Ming-hua|Hu, Xian-gui|Ni, Can-rong|Zhang, Shun-min|Xi, Peng-cheng|Yu, Guan-zhen
PMID: 16251039
Journal: Cancer Sci. 2006 Jan;97(1):1-7.
Title: Molecular mechanisms of pancreatic carcinogenesis.
Author: Furukawa, Toru|Sunamura, Makoto|Horii, Akira
PMID: 16367914
Journal: J Invest Dermatol. 2006 Mar;126(3):660-6.
Title: Population-based prevalence of CDKN2A mutations in Utah melanoma families.
Author: Eliason, Mark J|Larson, April A|Florell, Scott R|Zone, John J|Cannon-Albright, Lisa A|Samlowski, Wolfram E|Leachman, Sancy A
PMID: 16397522
Journal: Cancer Res. 2006 Jan 15;66(2):1208-17.
Title: DNA methylation alterations in the pancreatic juice of patients with suspected pancreatic disease.
Author: Matsubayashi, Hiroyuki|Canto, Marcia|Sato, Norihiro|Klein, Alison|Abe, Tadayoshi|Yamashita, Keishi|Yeo, Charles J|Kalloo, Anthony|Hruban, Ralph|Goggins, Michael
PMID: 16424060
Journal: Hepatobiliary Pancreat Dis Int. 2006 Feb;5(1):138-42.
Title: Expression of p53, p16 and COX-2 in pancreatic cancer with tissue microarray.
Author: Xu, Lei|Li, You-Ming|Yu, Chao-Hui|Li, Lan|Liu, You-Shi|Zhang, Bao-Feng|Fang, Jing|Zhou, Qiong|Hu, Ying|Gao, Hen-Jun
PMID: 16481301
Journal: Best Pract Res Clin Gastroenterol. 2006 Apr;20(2):211-26.
Title: Molecular pathogenesis of pancreatic cancer.
Author: Maitra, Anirban|Kern, Scott E|Hruban, Ralph H
PMID: 16549325
Journal: Best Pract Res Clin Gastroenterol. 2006 Apr;20(2):285-98.
Title: Gene therapy developments for pancreatic cancer.
Author: Bhattacharyya, Madhumita|Lemoine, Nick R
PMID: 16549328
Journal: Endocrinol Metab Clin North Am. 2006 Jun;35(2):417-30, xi.
Title: Familial pancreatic cancer syndromes.
Author: Habbe, Nils|Langer, Peter|Sina-Frey, Mercedes|Bartsch, Detlef K
PMID: 16632103
Journal: Zhonghua Yi Xue Za Zhi. 2006 Apr 11;86(14):939-42.
Title: [Detection of expression of p53, p16, and cyclooxygenase 2 in pancreatic cancer by tissue microarray and correlation among these three genes].
Author: Li, You-ming|Yu, Zhao-hui|Li, Lan|Xu, Ping|Li, Lin|Zhang, Bao-feng|Fang, Jing|Zhou, Qiong|Hu, Ying|Gao, Heng-jun
PMID: 16759529
Journal: Mol Cancer Ther. 2006 Jun;5(6):1387-95.
Title: Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer.
Author: Giovannetti, Elisa|Mey, Valentina|Nannizzi, Sara|Pasqualetti, Giuseppe|Del Tacca, Mario|Danesi, Romano
PMID: 16818496
Journal: J Carcinog. 2006 Jul 5;5:19.
Title: Characterization of pancreatic lesions from MT-tgf alpha, Ela-myc and MT-tgf alpha/Ela-myc single and double transgenic mice.
Author: Liao, Dezhong Joshua|Wang, Yong|Wu, Jiusheng|Adsay, Nazmi Volkan|Grignon, David|Khanani, Fayyaz|Sarkar, Fazlul H
PMID: 16822304
Journal: Anticancer Res. 2006 Jul-Aug;26(4B):3105-10.
Title: Immunohistochemical expression of 14-3-3 sigma protein in intraductal papillary-mucinous tumor and invasive ductal carcinoma of the pancreas.
Author: Okada, Toshiyuki|Masuda, Norihiro|Fukai, Yasuyuki|Shimura, Tatsuo|Nishida, Yasuji|Hosouchi, Yasuo|Kashiwabara, Kenji|Nakajima, Takashi|Kuwano, Hiroyuki
PMID: 16886641
Journal: Magy Onkol. 2006;50(2):163-8.
Title: [Familial pancreatic cancer].
Author: Zalatnai, Attila
PMID: 16888680
Journal: Hum Mol Genet. 2006 Sep 15;15(18):2682-9. Epub 2006 Aug 7.
Title: Impact of E27X, a novel CDKN2A germ line mutation, on p16 and p14ARF expression in Italian melanoma families displaying pancreatic cancer and neuroblastoma.
Author: Ghiorzo, Paola|Gargiulo, Sara|Pastorino, Lorenza|Nasti, Sabina|Cusano, Roberto|Bruno, William|Gliori, Sara|Sertoli, Mario R|Burroni, Anna|Savarino, Vincenzo|Gensini, Francesca|Sestini, Roberta|Queirolo, Paola|Goldstein, Alisa M|Scarra, Giovanna Bianchi
PMID: 16893909
Journal: Med Sci Monit. 2006 Sep;12(9):RA186-93.
Title: Molecular pathogenesis of pancreatic adenocarcinoma: potential clinical implications.
Author: Talar-Wojnarowska, Renata|Malecka-Panas, Ewa
PMID: 16940943
Journal: J Biol Chem. 2006 Dec 8;281(49):38080-8.
Title: Physical and functional interaction of the p14ARF tumor suppressor with ribosomes.
Author: Rizos, Helen|McKenzie, Heather A|Ayub, Ana Luisa|Woodruff, Sarah|Becker, Therese M|Scurr, Lyndee L|Stahl, Joachim|Kefford, Richard F
PMID: 17035234
Journal: Cancer Res. 2006 Oct 15;66(20):9818-28.
Title: High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL.
Author: Goldstein, Alisa M|Chan, May|Harland, Mark|Gillanders, Elizabeth M|Hayward, Nicholas K|Avril, Marie-Francoise|Azizi, Esther|Bianchi-Scarra, Giovanna|Bishop, D Timothy|Bressac-de Paillerets, Brigitte|Bruno, William|Calista, Donato|Cannon Albright, Lisa A|D
PMID: 17047042
Journal: Cancer Biol Ther. 2006 Oct;5(10):1392-9. Epub 2006 Oct 30.
Title: Detecting low-abundance p16 and p53 mutations in pancreatic juice using a novel assay: heteroduplex analysis of limiting dilution PCRs.
Author: Bian, Yansong|Matsubayashi, Hiroyuki|Li, Chung-Pin|Abe, Tadayoshi|Canto, Marcia|Murphy, Kathleen M|Goggins, Michael
PMID: 17106238
Journal: Praxis (Bern 1994). 2006 Nov 1;95(44):1709-12.
Title: [Pancreatic cancer].
Author: Schmid, R M
PMID: 17111879
Journal: Genes Dev. 2006 Nov 15;20(22):3130-46.
Title: Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Author: Bardeesy, Nabeel|Cheng, Kuang-Hung|Berger, Justin H|Chu, Gerald C|Pahler, Jessica|Olson, Peter|Hezel, Aram F|Horner, James|Lauwers, Gregory Y|Hanahan, Douglas|DePinho, Ronald A
PMID: 17114584
Journal: J Med Genet. 2007 Feb;44(2):99-106. Epub 2006 Aug 11.
Title: Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents.
Author: Goldstein, Alisa M|Chan, May|Harland, Mark|Hayward, Nicholas K|Demenais, Florence|Bishop, D Timothy|Azizi, Esther|Bergman, Wilma|Bianchi-Scarra, Giovanna|Bruno, William|Calista, Donato|Albright, Lisa A Cannon|Chaudru, Valerie|Chompret, Agnes|Cuellar, Fran
PMID: 16905682
Journal: Pancreas. 2007 Jan;34(1):55-62.
Title: K-ras mutation and p16 and preproenkephalin promoter hypermethylation in plasma DNA of pancreatic cancer patients: in relation to cigarette smoking.
Author: Jiao, Li|Zhu, Jijiang|Hassan, Manal M|Evans, Douglas B|Abbruzzese, James L|Li, Donghui
PMID: 17198183
Journal: Pancreas. 2007 Jan;34(1):85-91.
Title: Different patterns of p16INK4A and p53 protein expressions in intraductal papillary-mucinous neoplasms and pancreatic intraepithelial neoplasia.
Author: Abe, Keiko|Suda, Koichi|Arakawa, Atsushi|Yamasaki, Shigetaka|Sonoue, Hiroshi|Mitani, Keiko|Nobukawa, Bunsei
PMID: 17198188
Journal: Int J Cancer. 2007 May 15;120(10):2157-64.
Title: Analysis of molecular pathways in sporadic neuroendocrine tumors of the gastro-entero-pancreatic system.
Author: Arnold, Christian N|Sosnowski, Andrea|Schmitt-Graff, Annette|Arnold, Rudolf|Blum, Hubert E
PMID: 17278096
Journal: Cancer Biol Ther. 2007 Mar;6(3):320-3. Epub 2007 Mar 15.
Title: Linkage analysis of chromosome 4 in families with familial pancreatic cancer.
Author: Klein, Alison P|de Andrade, Mariza|Hruban, Ralph H|Bondy, Melissa|Schwartz, Ann G|Gallinger, Steven|Lynch, Henry T|Syngal, Sapna|Rabe, Kari G|Goggins, Michael G|Petersen, Gloria M
PMID: 17312386
Journal: Cancer Cell. 2007 Mar;11(3):229-43.
Title: Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas.
Author: Izeradjene, Kamel|Combs, Chelsea|Best, Melissa|Gopinathan, Aarthi|Wagner, Amary|Grady, William M|Deng, Chu-Xia|Hruban, Ralph H|Adsay, N Volkan|Tuveson, David A|Hingorani, Sunil R
PMID: 17349581
Journal: Dig Surg. 2007;24(1):38-45.
Title: Long-term survival after radical resection for pancreatic head and ampullary cancer: a potential role for the EGF-R.
Author: Smeenk, H G|Erdmann, J|van Dekken, H|van Marion, R|Hop, W C J|Jeekel, J|van Eijck, C H J
PMID: 17369680
Journal: Future Oncol. 2007 Apr;3(2):169-81.
Title: Hereditary cancer syndrome diagnosis: molecular genetic clues and cancer control.
Author: Lynch, Henry T|Fusaro, Ramon M|Lynch, Jane F
PMID: 17381417
Journal: World J Surg. 2007 May;31(5):1135-41.
Title: Differential expressions of cyclin D1 associated with better prognosis of cancers of ampulla of Vater.
Author: Chang, Ming-Chug|Chang, Yu-Ting|Sun, Chia-Tung|Chiu, Yen-Feng|Lin, Jaw-Town|Tien, Yu-Wen
PMID: 17420962
Journal: Clin Cancer Res. 2007 May 15;13(10):3100-4.
Title: Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians.
Author: Chen, Jinyun|Li, Donghui|Wei, Chongjuan|Sen, Subrata|Killary, Ann M|Amos, Christopher I|Evans, Douglas B|Abbruzzese, James L|Frazier, Marsha L
PMID: 17505013
Journal: J Hepatobiliary Pancreat Surg. 2007;14(3):238-42.
Title: Mucinous cystic neoplasms of the pancreas: pathology and molecular genetics.
Author: Fukushima, Noriyoshi|Fukayama, Masashi
PMID: 17520198
Journal: FEBS J. 2007 Jul;274(13):3233-56.
Title: Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells.
Author: Andre, Sabine|Sanchez-Ruderisch, Hugo|Nakagawa, Hiroaki|Buchholz, Malte|Kopitz, Jurgen|Forberich, Pia|Kemmner, Wolfgang|Bock, Corina|Deguchi, Kisaburo|Detjen, Katharia M|Wiedenmann, Bertram|von Knebel Doeberitz, Magnus|Gress, Thomas M|Nishimura, Shin-Ichi
PMID: 17535296
Journal: Int J Cancer. 2007 Oct 1;121(7):1410-6.
Title: Overexpression of ErbB2 in the exocrine pancreas induces an inflammatory response but not increased proliferation.
Author: Algul, Hana|Wagner, Martin|Lesina, Marina|Schmid, Roland M
PMID: 17546589
Journal: Cell Cycle. 2007 Jul 1;6(13):1553-7.
Title: Shh signaling and pancreatic cancer: implications for therapy?
Author: Morton, Jennifer P|Lewis, Brian C
PMID: 17611415
Journal: Cell Cycle. 2007 Jul 15;6(14):1741-7. Epub 2007 May 10.
Title: p14ARF regulates E2F-1 ubiquitination and degradation via a p53-dependent mechanism.
Author: Rizos, Helen|Scurr, Lyndee L|Irvine, Mal|Alling, Nikki J|Kefford, Richard F
PMID: 17630509
Journal: Mod Pathol. 2007 Sep;20(9):955-60. Epub 2007 Jul 13.
Title: Solid pseudopapillary neoplasms of the pancreas show an interruption of the Wnt-signaling pathway and express gene products of 11q.
Author: Tiemann, Katharina|Heitling, Ulrike|Kosmahl, Markus|Kloppel, Gunter
PMID: 17632456
Journal: World J Gastroenterol. 2007 Jul 21;13(27):3714-20.
Title: Evaluation of clinical relevance of examining K-ras, p16 and p53 mutations along with allelic losses at 9p and 18q in EUS-guided fine needle aspiration samples of patients with chronic pancreatitis and pancreatic cancer.
Author: Salek, C|Benesova, L|Zavoral, M|Nosek, V|Kasperova, L|Ryska, M|Strnad, R|Traboulsi, E|Minarik, M
PMID: 17659731
Journal: Am J Surg Pathol. 2007 Aug;31(8):1191-5.
Title: Pancreatic intraepithelial neoplasia in heterotopic pancreas: evidence for the progression model of pancreatic ductal adenocarcinoma.
Author: Zhang, Lizhi|Sanderson, Schuyler O|Lloyd, Ricardo V|Smyrk, Thomas C
PMID: 17667542
Journal: Curr Mol Med. 2007 Aug;7(5):504-21.
Title: Molecular pathogenesis of pancreatic cancer: advances and challenges.
Author: Welsch, Thilo|Kleeff, Jorg|Friess, Helmut
PMID: 17691965
Journal: World J Gastroenterol. 2007 Aug 21;13(31):4214-8.
Title: Construction of targeted plasmid vector pcDNA3.1-Egr.1p-p16 and its expression in pancreatic cancer JF305 cells induced by radiation in vitro.
Author: Ma, Hong-Bing|Wang, Xi-Jing|Di, Zheng-Li|Xia, Hui|Li, Zheng|Liu, Jie|Ma, Jie|Kang, Hua-Fen|Wu, Cong-Mei|Bai, Ming-Hua
PMID: 17696250
Journal: Pancreatology. 2007;7(4):352-9. Epub 2007 Aug 15.
Title: Identification of methylation-associated gene expression in neuroendocrine pancreatic tumor cells.
Author: Habbe, Nils|Bert, Tillmann|Simon, Babette
PMID: 17703082
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2007 Aug;27(8):1183-6.
Title: [Effect of irradiation-induced pcDNA3.1-Egr.1p-p16 on cell apoptosis and cell cycle of JF305 cells].
Author: Ma, Hong-Bing|Wang, Xi-Jing|Ma, Jie|Xia, Hui|Wang, Zheng|Li, Zheng|Han, Zhi-Kai|Wu, Cong-Mei
PMID: 17715021
Journal: Expert Opin Ther Targets. 2007 Dec;11(12):1553-69.
Title: Molecular prognostic factors in patients with pancreatic cancer.
Author: Tonini, Giuseppe|Pantano, Francesco|Vincenzi, Bruno|Gabbrielli, Armando|Coppola, Roberto|Santini, Daniele
PMID: 18020978
Journal: J Clin Oncol. 2007 Nov 20;25(33):5336-7; author reply 5337-8.
Title: Predicting the risk of pancreatic cancer: on CDKN2A mutations in the melanoma-pancreatic cancer syndrome in Italy.
Author: Ghiorzo, Paola|Gargiulo, Sara|Nasti, Sabina|Pastorino, Lorenza|Battistuzzi, Linda|Bruno, William|Bonelli, Luigina|Taveggia, Paola|Pugliese, Vittorio|Borgonovo, Giacomo|Mastracci, Luca|Fornarini, Giuseppe|Romagnoli, Paola|Iiritano, Elena|Savarino, Vincenzo
PMID: 18024887
Journal: BMC Cancer. 2007 Nov 25;7:217.
Title: Aberrant overexpression of an epithelial marker, 14-3-3sigma, in a subset of hematological malignancies.
Author: Motokura, Toru|Nakamura, Yukari|Sato, Hiroyuki
PMID: 18036248
Journal: Semin Oncol. 2007 Dec;34(6):452-9.
Title: Genetics: what advice for patients who present with a family history of melanoma?
Author: Newton Bishop, Julia A|Gruis, Nelleke A
PMID: 18083368
Journal: Expert Rev Gastroenterol Hepatol. 2007 Oct;1(1):81-8.
Title: Familial pancreatic cancer: from genes to improved patient care.
Author: Hruban, Ralph H|Klein, Alison P|Eshleman, James R|Axilbund, Jennifer E|Goggins, Michael
PMID: 19072437
Journal: J Invest Dermatol. 2008 Feb;128(2):421-5.
Title: Clinical and molecular characterization of patients at risk for hereditary melanoma in southern Brazil.
Author: Ashton-Prolla, Patricia|Bakos, Lucio|Junqueira, Gerson Jr|Giugliani, Roberto|Azevedo, Sergio J|Hogg, David
PMID: 17713569
Journal: Fam Cancer. 2008;7(1):103-12. Epub 2007 Nov 9.
Title: Pancreatic cancer and the FAMMM syndrome.
Author: Lynch, Henry T|Fusaro, Ramon M|Lynch, Jane F|Brand, Randall
PMID: 17992582
Journal: Annu Rev Pathol. 2008;3:157-88.
Title: Pancreatic cancer.
Author: Maitra, Anirban|Hruban, Ralph H
PMID: 18039136
Journal: J Med Genet. 2008 May;45(5):284-9.
Title: CDKN2A mutations and melanoma risk in the Icelandic population.
Author: Goldstein, A M|Stacey, S N|Olafsson, J H|Jonsson, G F|Helgason, A|Sulem, P|Sigurgeirsson, B|Benediktsdottir, K R|Thorisdottir, K|Ragnarsson, R|Kjartansson, J|Kostic, J|Masson, G|Kristjansson, K|Gulcher, J R|Kong, A|Thorsteinsdottir, U|Rafnar, T|Tucker, M
PMID: 18178632
Journal: Langenbecks Arch Surg. 2008 Nov;393(6):883-90.
Title: Molecular markers of pancreatic cancer: development and clinical relevance.
Author: Fry, Lucia C|Monkemuller, Klaus|Malfertheiner, Peter
PMID: 18266003
Journal: Eur J Endocrinol. 2008 Mar;158(3):417-22.
Title: Uncommon association of germline mutations of RET proto-oncogene and CDKN2A gene.
Author: Foppiani, L|Forzano, F|Ceccherini, I|Bruno, W|Ghiorzo, P|Caroli, F|Quilici, P|Bandelloni, R|Arlandini, A|Sartini, G|Cabria, M|Del Monte, P
PMID: 18299477
Journal: Am J Pathol. 2008 Apr;172(4):1081-7.
Title: Trp53 deletion stimulates the formation of metastatic pancreatic tumors.
Author: Morton, Jennifer P|Klimstra, David S|Mongeau, Michelle E|Lewis, Brian C
PMID: 18310506
Journal: Mol Cell Biol. 2008 May;28(10):3219-35.
Title: Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter.
Author: Wu, Li-Peng|Wang, Xi|Li, Lian|Zhao, Ying|Lu, Shaoli|Yu, Yu|Zhou, Wen|Liu, Xiangyu|Yang, Jing|Zheng, Zhixin|Zhang, Hui|Feng, Jingnan|Yang, Yang|Wang, Haiying|Zhu, Wei-Guo
PMID: 18332107
Journal: J Hepatobiliary Pancreat Surg. 2008;15(2):169-77.
Title: Characterization of K-ras gene mutations in association with mucinous hypersecretion in intraductal papillary-mucinous neoplasms.
Author: Kobayashi, Noritoshi|Inamori, Masahiko|Fujita, Koji|Fujisawa, Toshio|Fujisawa, Nobutaka|Takahashi, Hirokazu|Yoneda, Masato|Abe, Yasunobu|Kawamura, Harunobu|Shimamura, Takeshi|Kirikoshi, Hiroyuki|Kubota, Kensuke|Sakaguchi, Takashi|Saito, Satoru|Saubermann,
PMID: 18392710
Journal: Gut. 2008 Oct;57(10):1420-30.
Title: Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer.
Author: Feldmann, G|Habbe, N|Dhara, S|Bisht, S|Alvarez, H|Fendrich, V|Beaty, R|Mullendore, M|Karikari, C|Bardeesy, N|Ouellette, M M|Yu, W|Maitra, A
PMID: 18515410
Journal: Bull Cancer. 2008 May;95(5):503-12.
Title: [New molecular targets in pancreatic cancer].
Author: Torrisani, Jerome|Bournet, Barbara|Cordelier, Pierre|Buscail, Louis
PMID: 18541514
Journal: Hum Pathol. 2008 Aug;39(8):1205-11.
Title: Expression of RNA-binding protein IMP3 (KOC) in benign urothelium and urothelial tumors.
Author: Li, Lin|Xu, Haodong|Spaulding, Betsy O|Cheng, Liang|Simon, Rochelle|Yao, Jorge L|di Sant'Agnese, P Anthony|Bourne, Patricia A|Huang, Jiaoti
PMID: 18547613
Journal: Br J Cancer. 2008 Jul 8;99(1):110-7.
Title: Inducible re-expression of p16 in an orthotopic mouse model of pancreatic cancer inhibits lymphangiogenesis and lymphatic metastasis.
Author: Schulz, P|Scholz, A|Rexin, A|Hauff, P|Schirner, M|Wiedenmann, B|Detjen, K
PMID: 18577984
Journal: Psychooncology. 2008 Aug;17(8):790-6.
Title: Genetic testing in familial melanoma: uptake and implications.
Author: de Snoo, Femke A|Riedijk, Samantha R|van Mil, Anneke M|Bergman, Wilma|ter Huurne, Jeanet A C|Timman, Reinier|Bertina, Wieke|Gruis, Nelleke A|Vasen, Hans F A|van Haeringen, Arie|Breuning, Martijn H|Tibben, Aad
PMID: 18613292
Journal: Eur J Gastroenterol Hepatol. 2008 Aug;20(8):713-5.
Title: Pancreatic cancer: a plea for good and comprehensive morphological studies.
Author: Algul, Hana|Schmid, Roland M
PMID: 18617774
Journal: Surg Clin North Am. 2008 Aug;88(4):897-916, viii.
Title: Familial melanoma.
Author: Hansson, Johan
PMID: 18672145
Journal: Gastrointest Endosc Clin N Am. 2008 Jul;18(3):535-53, x.
Title: Screening and surveillance approaches in familial pancreatic cancer.
Author: Canto, Marcia Irene
PMID: 18674702
Journal: Cancer Sci. 2008 Sep;99(9):1859-64.
Title: Establishment and molecular profiling of a novel human pancreatic cancer panel for 5-FU.
Author: Yanagihara, Kazuyoshi|Takigahira, Misato|Tanaka, Hiromi|Arao, Tokuzo|Aoyagi, Yasuyuki|Oda, Tatsuya|Ochiai, Atsushi|Nishio, Kazuto
PMID: 18691340
Journal: Hepatobiliary Pancreat Dis Int. 2008 Aug;7(4):345-56.
Title: Molecular aspects of carcinogenesis in pancreatic cancer.
Author: Koliopanos, Alexandros|Avgerinos, Constantinos|Paraskeva, Constantina|Touloumis, Zisis|Kelgiorgi, Dionisisa|Dervenis, Christos
PMID: 18693168
Journal: Eur J Cancer Prev. 2008 Oct;17(5):389-91.
Title: Low prevalence of CDKN2A/ARF mutations among early-onset cancers of breast, pancreas and malignant melanoma in Poland.
Author: Debniak, Tadeusz|van de Wetering, Thierry|Scott, Rodney|Nagay, Leszek|Cybulski, Cezary|Gorski, Bohdan|Jakubowska, Anna|Gronwald, Jacek|Masojc, Bartlomiej|Huzarski, Tomasz|Byrski, Tomasz|Nej-Wolosiak, Katarzyna|Kladny, Jozef|Maleszka, Romuald|Lubinski, Jan
PMID: 18714178
Journal: Am J Surg Pathol. 2008 Dec;32(12):1905-9.
Title: Undifferentiated carcinoma with osteoclastic giant cells (UCOCGC) of the pancreas associated with the familial atypical multiple mole melanoma syndrome (FAMMM).
Author: Koorstra, Jan-Bart M|Maitra, Anirban|Morsink, Folkert H M|Drillenburg, Paul|ten Kate, Fiebo J W|Hruban, Ralph H|Offerhaus, Johan A
PMID: 18813118
Journal: Pancreatology. 2008;8(6):558-65.
Title: International registries of families at high risk of pancreatic cancer.
Author: Greenhalf, William|Malats, Nuria|Nilsson, Magnus|Bartsch, Detlef|Neoptolemos, John
PMID: 18818508
Journal: Oncol Rep. 2008 Nov;20(5):1053-9.
Title: Lentiviral-mediated Smad4 RNAi induced anti-proliferation by p16 up-regulation and apoptosis by caspase 3 down-regulation in hepatoma SMMC-7721 cells.
Author: Huang, Shu|Zhang, Faming|Miao, Lin|Zhang, Huijie|Fan, Zhining|Wang, Xuehao|Ji, Guozhong
PMID: 18949401
Journal: Clin Cancer Res. 2008 Nov 1;14(21):7151-7.
Title: Increased risk of cancer other than melanoma in CDKN2A founder mutation (p16-Leiden)-positive melanoma families.
Author: de Snoo, Femke A|Bishop, D Timothy|Bergman, Wilma|van Leeuwen, Inge|van der Drift, Clasine|van Nieuwpoort, Frans A|Out-Luiting, Coby J|Vasen, Hans F|ter Huurne, Jeanet A C|Frants, Rune R|Willemze, Rein|Breuning, Martijn H|Gruis, Nelleke A
PMID: 18981015
Journal: Zhonghua Yi Xue Za Zhi. 2008 Jul 22;88(28):1948-51.
Title: [Activation of multiple tumor suppressor genes by MBD1 siRNA in pancreatic cancer cell line BxPC-3].
Author: Xu, Jin|Liu, Chen|Yu, Xian-jun|Jin, Chen|Fu, De-liang|Ni, Quan-xing
PMID: 19062732
Journal: Pol Arch Med Wewn. 2008 Nov;118(11):645-9.
Title: Is there any relationship between BRCA1 gene mutation and pancreatic cancer development?
Author: Lawniczak, Malgorzata|Gawin, Alicja|Bialek, Andrzej|Lubinski, Jan|Starzynska, Teresa
PMID: 19140568
Journal: Gut Liver. 2008 Dec;2(3):137-54.
Title: Precursor lesions of pancreatic cancer.
Author: Yonezawa, Suguru|Higashi, Michiyo|Yamada, Norishige|Goto, Masamichi
PMID: 20485640
Journal: Appl Immunohistochem Mol Morphol. 2009 Jan;17(1):31-9.
Title: Histologic, immunohistochemical, and molecular classification of 52 IPMNs of the pancreas.
Author: Chadwick, Barbara|Willmore-Payne, Carlynn|Tripp, Sheryl|Layfield, Lester J|Hirschowitz, Sharon|Holden, Joseph
PMID: 18813127
Journal: Pancreas. 2009 Mar;38(2):184-96.
Title: Establishment and characterization of 4 new human pancreatic cancer cell lines: evidences of different tumor phenotypes.
Author: Chifenti, Barbara|Morelli, Mariangela|Zavaglia, Michele|Coviello, Domenico A|Guerneri, Silvana|Santucci, Annalisa|Paffetti, Alessandro|Masetti, Massimo|Locci, Maria Teresa|Bertacca, Gloria|Capodanno, Alessandra|Collecchi, Paola|Campani, Daniela|Mosca, Fra
PMID: 19002021
Journal: Ann Surg Oncol. 2009 Feb;16(2):431-9.
Title: Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation.
Author: Chen, Jinyun|Li, Donghui|Killary, Ann M|Sen, Subrata|Amos, Christopher I|Evans, Douglas B|Abbruzzese, James L|Frazier, Marsha L
PMID: 19020940
Journal: J Gastrointest Surg. 2009 Jun;13(6):1151-4.
Title: Novel presentation of a familial pancreatic cancer syndrome.
Author: Maker, Ajay V|Warth, James A|Zinner, Michael J
PMID: 19089513
Journal: Mutat Res. 2009 Mar-Jun;681(2-3):299-307.
Title: Genetic predisposition and environmental risk factors to pancreatic cancer: A review of the literature.
Author: Landi, Stefano
PMID: 19150414
Journal: Ann Surg Oncol. 2009 Apr;16(4):1051-9.
Title: Positive regulation of human telomerase reverse transcriptase gene expression and telomerase activity by DNA methylation in pancreatic cancer.
Author: Kumari, Alpana|Srinivasan, Radhika|Vasishta, Rakesh Kumar|Wig, Jai Dev
PMID: 19194757
Journal: Cancer Lett. 2009 Jun 18;278(2):230-40.
Title: Expression of TBX2 promotes anchorage-independent growth and survival in the p53-negative SW13 adrenocortical carcinoma.
Author: Ismail, Amin|Bateman, Andrew
PMID: 19216023
Journal: Mod Pathol. 2009 May;22(5):651-9.
Title: Adenosquamous carcinoma of the pancreas harbors KRAS2, DPC4 and TP53 molecular alterations similar to pancreatic ductal adenocarcinoma.
Author: Brody, Jonathan R|Costantino, Christina L|Potoczek, Magdalena|Cozzitorto, Joseph|McCue, Peter|Yeo, Charles J|Hruban, Ralph H|Witkiewicz, Agnieszka K
PMID: 19270646
Journal: Cancer Res. 2009 Apr 15;69(8):3681-8.
Title: Genetic mutations associated with cigarette smoking in pancreatic cancer.
Author: Blackford, Amanda|Parmigiani, Giovanni|Kensler, Thomas W|Wolfgang, Christopher|Jones, Sian|Zhang, Xiaosong|Parsons, D Willams|Lin, Jimmy Cheng-Ho|Leary, Rebecca J|Eshleman, James R|Goggins, Michael|Jaffee, Elizabeth M|Iacobuzio-Donahue, Christine A|Maitra
PMID: 19351817
Journal: Head Neck. 2009 Nov;31(11):1524-7.
Title: Head and neck squamous cell carcinoma in FAMMM syndrome.
Author: Vinarsky, Vladimir|Fine, Robert L|Assaad, Adel|Qian, Ying|Chabot, John A|Su, Gloria H|Frucht, Harold
PMID: 19360740
Journal: J Clin Gastroenterol. 2009 Oct;43(9):853-7.
Title: Atypical familial presentation of FAMMM syndrome with a high incidence of pancreatic cancer: case finding of asymptomatic individuals by EUS surveillance.
Author: Kluijt, Irma|Cats, Annemieke|Fockens, Paul|Nio, Yung|Gouma, Dirk J|Bruno, Marco J
PMID: 19417680
Journal: Anticancer Res. 2009 May;29(5):1803-10.
Title: Mutation status of K-ras, p53 and allelic losses at 9p and 18q are not prognostic markers in patients with pancreatic cancer.
Author: Salek, Cyril|Minarikova, Petra|Benesova, Lucie|Nosek, Vladimir|Strnad, Robin|Zavoral, Miroslav|Minarik, Marek
PMID: 19443408
Journal: PLoS One. 2009 May 29;4(5):e5735.
Title: Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy.
Author: Lubin, Martin|Lubin, Adam
PMID: 19478948
Journal: Clin Cancer Res. 2009 Jul 15;15(14):4674-9.
Title: SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.
Author: Blackford, Amanda|Serrano, Oscar K|Wolfgang, Christopher L|Parmigiani, Giovanni|Jones, Sian|Zhang, Xiaosong|Parsons, D Williams|Lin, Jimmy Cheng-Ho|Leary, Rebecca J|Eshleman, James R|Goggins, Michael|Jaffee, Elizabeth M|Iacobuzio-Donahue, Christine A|Mait
PMID: 19584151
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2549-52.
Title: Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.
Author: McWilliams, Robert R|Bamlet, William R|de Andrade, Mariza|Rider, David N|Couch, Fergus J|Cunningham, Julie M|Matsumoto, Martha E|Rabe, Kari G|Hammer, Traci J|Petersen, Gloria M
PMID: 19690177
Journal: Mayo Clin Proc. 2009 Sep;84(9):801-10.
Title: Fluorescence in situ hybridization to visualize genetic abnormalities in interphase cells of acinar cell carcinoma, ductal adenocarcinoma, and islet cell carcinoma of the pancreas.
Author: Dewald, Gordon W|Smyrk, Thomas C|Thorland, Erik C|McWilliams, Robert R|Van Dyke, Daniel L|Keefe, Jeannette G|Belongie, Kimberly J|Smoley, Stephanie A|Knutson, Darlene L|Fink, Stephanie R|Wiktor, Anne E|Petersen, Gloria M
PMID: 19720778
Journal: J Am Acad Dermatol. 2009 Oct;61(4):677.e1-14.
Title: Selection criteria for genetic assessment of patients with familial melanoma.
Author: Leachman, Sancy A|Carucci, John|Kohlmann, Wendy|Banks, Kimberly C|Asgari, Maryam M|Bergman, Wilma|Bianchi-Scarra, Giovanna|Brentnall, Teresa|Bressac-de Paillerets, Brigitte|Bruno, William|Curiel-Lewandrowski, Clara|de Snoo, Femke A|Debniak, Tadeusz|Demier
PMID: 19751883
Journal: Clin Gastroenterol Hepatol. 2009 Nov;7(11 Suppl):S35-9.
Title: Molecular pathology of pancreatic cancer: implications for molecular targeting therapy.
Author: Furukawa, Toru
PMID: 19896096
Journal: Clin Gastroenterol Hepatol. 2009 Nov;7(11 Suppl):S55-8.
Title: Differentiating neoplastic from benign lesions of the pancreas: translational techniques.
Author: Khalid, Asif
PMID: 19896100
Journal: Eur J Gynaecol Oncol. 2009;30(6):661-3.
Title: Incidence of multiple primary malignancies in women diagnosed with breast cancer.
Author: Stracci, F|D'Alo, D|Cassetti, T|Scheibel, M|La Rosa, F
PMID: 20099499
Journal: Ecancermedicalscience. 2009;3:131.
Title: Detection of methylation in the CpG islands of the p16INK4A, RASSF 1A and methylguanine methyltransferase gene promoters in pancreatic adenocarcinoma.
Author: Paikos, D|Stravoravdi, P|Voyatzi, S|Boukovinas, I|Papakotoulas, P|Kiziridou, A|Sibilidis, G|Stergiou, I
PMID: 22276000
Journal: Neuroendocrinology. 2010;91(2):131-41.
Title: Spectral karyotypic and comparative genomic analysis of the endocrine pancreatic tumor cell line BON-1.
Author: Lopez, Juan R|Claessen, Sandra M H|Macville, Merryn V E|Albrechts, Jozefa C M|Skogseid, Britt|Speel, Ernst-Jan M
PMID: 19887762
Journal: Clin Genet. 2010 Apr;77(4):333-41.
Title: Clinical and genetic analysis of 18 pancreatic carcinoma/melanoma-prone families.
Author: Bartsch, D K|Langer, P|Habbe, N|Matthai, E|Chaloupka, B|Sina, M|Hahn, S A|Slater, E P
PMID: 20041885
Journal: Fam Cancer. 2010 Sep;9(3):335-43.
Title: Prevalence of BRCA2 and CDKN2a mutations in German familial pancreatic cancer families.
Author: Slater, Emily P|Langer, Peter|Fendrich, Volker|Habbe, Nils|Chaloupka, Brunhilde|Matthai, Elvira|Sina, Mercedes|Hahn, Stephan A|Bartsch, Detlef K
PMID: 20195775
Journal: Pancreas. 2010 May;39(4):425-35.
Title: Phenotype and genotype of pancreatic cancer cell lines.
Author: Deer, Emily L|Gonzalez-Hernandez, Jessica|Coursen, Jill D|Shea, Jill E|Ngatia, Josephat|Scaife, Courtney L|Firpo, Matthew A|Mulvihill, Sean J
PMID: 20418756
Journal: Pancreas. 2010 Oct;39(7):1093-103.
Title: Genomic instability at both the base pair level and the chromosomal level is detectable in earliest PanIN lesions in tissues of chronic pancreatitis.
Author: Baumgart, Mario|Werther, Meike|Bockholt, Anke|Scheurer, Maria|Ruschoff, Josef|Dietmaier, Wolfgang|Ghadimi, B Michael|Heinmoller, Ernst
PMID: 20531246
Journal: Cancer Biol Ther. 2010 Sep 15;10(6):582-7. Epub 2010 Oct 1.
Title: Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annotation of somatic mutations (CHASM).
Author: Carter, Hannah|Samayoa, Josue|Hruban, Ralph H|Karchin, Rachel
PMID: 20581473
Journal: Cancer. 2010 Nov 15;116(22):5179-87.
Title: Expression of p16(INK4A) but not hypoxia markers or poly adenosine diphosphate-ribose polymerase is associated with improved survival in patients with pancreatic adenocarcinoma.
Author: Chang, Daniel T|Chapman, Christopher H|Norton, Jeffrey A|Visser, Brendan|Fisher, George A|Kunz, Pamela|Ford, James M|Koong, Albert C|Pai, Reetesh K
PMID: 20665497
Journal: Adv Exp Med Biol. 2010;685:134-45.
Title: Familial cutaneous melanoma.
Author: Hansson, Johan
PMID: 20687502
Journal: FEBS J. 2010 Sep;277(17):3552-63.
Title: Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model.
Author: Sanchez-Ruderisch, Hugo|Fischer, Christian|Detjen, Katharina M|Welzel, Martina|Wimmel, Anja|Manning, Joachim C|Andre, Sabine|Gabius, Hans-Joachim
PMID: 20695889
Journal: Clin Cancer Res. 2010 Oct 15;16(20):5028-37.
Title: Pancreatic cancer screening in a prospective cohort of high-risk patients: a comprehensive strategy of imaging and genetics.
Author: Verna, Elizabeth C|Hwang, Caroline|Stevens, Peter D|Rotterdam, Heidrun|Stavropoulos, Stavros N|Sy, Carolyn D|Prince, Martin A|Chung, Wendy K|Fine, Robert L|Chabot, John A|Frucht, Harold
PMID: 20876795
Journal: Anticancer Res. 2010 Dec;30(12):4907-13.
Title: Gender differences in gemcitabine (Gemzar) efficacy in cancer cells: effect of indole-3-carbinol.
Author: Lyn-Cook, Beverly D|Mohammed, Sulma I|Davis, Cornelius|Word, Beverly|Haefele, Aaron|Wang, Honggang|Hammons, George
PMID: 21187469
Journal: Anticancer Agents Med Chem. 2010 Dec;10(10):742-6.
Title: FAK and interacting proteins as therapeutic targets in pancreatic cancer.
Author: Ucar, Deniz A|Hochwald, Steven N
PMID: 21235432
Journal: Cancer Biomark. 2010;9(1-6):421-40.
Title: Molecular pathology of early pancreatic cancer.
Author: Remmers, Neeley|Bailey, Jennifer M|Mohr, Ashley M|Hollingsworth, Michael A
PMID: 22112488
Journal: Cancers (Basel). 2010 Nov 10;2(4):1861-83.
Title: Familial pancreatic cancer.
Author: Lynch, Henry T|Lynch, Jane F|Lanspa, Stephen J
PMID: 24281205
Journal: Gastroenterology. 2011 Mar;140(3):850-6.
Title: Magnetic resonance imaging surveillance detects early-stage pancreatic cancer in carriers of a p16-Leiden mutation.
Author: Vasen, Hans F A|Wasser, Martin|van Mil, Anneke|Tollenaar, Rob A|Konstantinovski, Marja|Gruis, Nelleke A|Bergman, Wilma|Hes, Frederik J|Hommes, Daniel W|Offerhaus, G Johan A|Morreau, Hans|Bonsing, Bert A|de Vos tot Nederveen Cappel, Wouter H
PMID: 21129377
Journal: Eur J Hum Genet. 2011 Apr;19(4):472-8.
Title: Prevalence of CDKN2A mutations in pancreatic cancer patients: implications for genetic counseling.
Author: McWilliams, Robert R|Wieben, Eric D|Rabe, Kari G|Pedersen, Katrina S|Wu, Yanhong|Sicotte, Hugues|Petersen, Gloria M
PMID: 21150883
Journal: Front Biosci (Elite Ed). 2011 Jan 1;3:750-6.
Title: Focal adhesion kinase signaling and function in pancreatic cancer.
Author: Ucar, Deniz A|Dang, Long H|Hochwald, Steven N
PMID: 21196348
Journal: Fam Cancer. 2011 Jun;10(2):323-30.
Title: German national case collection for familial pancreatic cancer (FaPaCa): ten years experience.
Author: Schneider, Ralph|Slater, Emily P|Sina, Mercede|Habbe, Nils|Fendrich, Volker|Matthai, Elvira|Langer, Peter|Bartsch, Detlef K
PMID: 21207249
Journal: Oncogene. 2011 May 5;30(18):2123-34.
Title: Oncogenic Ras/Src cooperativity in pancreatic neoplasia.
Author: Shields, D J|Murphy, E A|Desgrosellier, J S|Mielgo, A|Lau, S K M|Barnes, L A|Lesperance, J|Huang, M|Schmedt, C|Tarin, D|Lowy, A M|Cheresh, D A
PMID: 21242978
Journal: J Gastrointest Cancer. 2011 Jun;42(2):76-84.
Title: Pancreatic ductal adenocarcinoma and transcription factors: role of c-Myc.
Author: Skoudy, Anouchka|Hernandez-Munoz, Inmaculada|Navarro, Pilar
PMID: 21279552
Journal: J Gastrointest Cancer. 2011 Jun;42(2):93-9.
Title: Epigenetic silencing of tumor suppressor genes in pancreatic cancer.
Author: Lomberk, Gwen A
PMID: 21318291
Journal: Br J Cancer. 2011 Apr 26;104(9):1440-51.
Title: Meta-analysis of immunohistochemical prognostic markers in resected pancreatic cancer.
Author: Smith, R A|Tang, J|Tudur-Smith, C|Neoptolemos, J P|Ghaneh, P
PMID: 21448172
Journal: Pathol Res Pract. 2011 Jun 15;207(6):343-53.
Title: Dysregulation of the cell cycle and chromosomal imbalances in juxtaglomerular cell tumors - a comparative study with endocrine tumors of the pancreas.
Author: Assmann, Gerald|Verdorfer, Irmgard|Jung, Andreas|Bader, Markus|Muller-Hocker, Josef
PMID: 21482036
Journal: Clin Exp Dermatol. 2011 Oct;36(7):782-7.
Title: EDNRB gene variants and melanoma risk in two southern European populations.
Author: Spica, T|Fargnoli, M C|Hetet, G|Bertrand, G|Formicone, F|Descamps, V|Wolkenstein, P|Dupin, N|Lebbe, C|Basset-Seguin, N|Saiag, P|Cambien, F|Grandchamp, B|Peris, K|Soufir, N
PMID: 21507037
Journal: Dig Endosc. 2011 May;23 Suppl 1:43-5.
Title: Genetic diagnosis of pancreatic cancer using specimens obtained by EUS-FNA.
Author: Ryozawa, Shomei|Iwano, Hirotoshi|Taba, Kumiko|Sen-yo, Manabu|Uekitani, Toshiyuki
PMID: 21535200
Journal: PLoS One. 2011 May 12;6(5):e19721.
Title: Plasma proteome profiles associated with inflammation, angiogenesis, and cancer.
Author: Kelly-Spratt, Karen S|Pitteri, Sharon J|Gurley, Kay E|Liggitt, Denny|Chin, Alice|Kennedy, Jacob|Wong, Chee-Hong|Zhang, Qing|Buson, Tina Busald|Wang, Hong|Hanash, Samir M|Kemp, Christopher J
PMID: 21589862
Journal: World J Clin Oncol. 2011 May 10;2(5):195-202.
Title: Genetically-engineered mouse models for pancreatic cancer: Advances and current limitations.
Author: Ijichi, Hideaki
PMID: 21611096
Journal: Fam Cancer. 2011 Sep;10(3):545-8.
Title: Lack of germline PALB2 mutations in melanoma-prone families with CDKN2A mutations and pancreatic cancer.
Author: Yang, Xiaohong R|Jessop, Lea|Myers, Timothy|Amundadottir, Laufey|Pfeiffer, Ruth M|Wheeler, William|Pike, Kristen M|Yuenger, Jeff|Burdett, Laurie|Yeager, Meredith|Chanock, Stephen J|Tucker, Margaret A|Goldstein, Alisa M
PMID: 21614589
Journal: Cancer Radiother. 2011 Aug;15(5):365-75.
Title: [New perspectives for radiosensitization in pancreatic carcinoma: a review of mechanisms involved in pancreatic tumorigenesis].
Author: Huguet, F|Fernet, M|Monnier, L|Touboul, E|Favaudon, V
PMID: 21664851
Journal: Cancer Cell. 2011 Jun 14;19(6):728-39.
Title: Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence.
Author: Guerra, Carmen|Collado, Manuel|Navas, Carolina|Schuhmacher, Alberto J|Hernandez-Porras, Isabel|Canamero, Marta|Rodriguez-Justo, Manuel|Serrano, Manuel|Barbacid, Mariano
PMID: 21665147
Journal: Int J Mol Sci. 2011;12(3):1595-604.
Title: Cancer stem-like cells enriched in Panc-1 spheres possess increased migration ability and resistance to gemcitabine.
Author: Yin, Tao|Wei, Hongji|Gou, Shanmiao|Shi, Pengfei|Yang, Zhiyong|Zhao, Gang|Wang, Chunyou
PMID: 21673909
Journal: PLoS One. 2011;6(6):e20537.
Title: Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-kappaB signaling pathways.
Author: Wang, Zhiwei|Banerjee, Sanjeev|Ahmad, Aamir|Li, Yiwei|Azmi, Asfar S|Gunn, Jason R|Kong, Dejuan|Bao, Bin|Ali, Shadan|Gao, Jiankun|Mohammad, Ramzi M|Miele, Lucio|Korc, Murray|Sarkar, Fazlul H
PMID: 21673986
Journal: Gastroenterology. 2011 Sep;141(3):1091-101.
Title: Deletion of Rb accelerates pancreatic carcinogenesis by oncogenic Kras and impairs senescence in premalignant lesions.
Author: Carriere, Catherine|Gore, A Jesse|Norris, Alixanna M|Gunn, Jason R|Young, Alison L|Longnecker, Daniel S|Korc, Murray
PMID: 21699781
Journal: World J Gastroenterol. 2011 Jun 28;17(24):2897-908.
Title: Molecular biology of pancreatic cancer.
Author: Zavoral, Miroslav|Minarikova, Petra|Zavada, Filip|Salek, Cyril|Minarik, Marek
PMID: 21734801
Journal: Pancreas. 2011 Aug;40(6):905-10.
Title: Establishment and characterization of a new cell line, A99, from a primary small cell carcinoma of the pancreas.
Author: Yachida, Shinichi|Zhong, Yi|Patrascu, Raul|Davis, Meghan B|Morsberger, Laura A|Griffin, Constance A|Hruban, Ralph H|Laheru, Daniel|Iacobuzio-Donahue, Christine A
PMID: 21768923
Journal: Cancer Gene Ther. 2011 Oct;18(10):734-43.
Title: An oncolytic adenovirus defective in pRb-binding (dl922-947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine.
Author: Bhattacharyya, M|Francis, J|Eddouadi, A|Lemoine, N R|Hallden, G
PMID: 21836633
Journal: Curr Genomics. 2011 Mar;12(1):15-24.
Title: Genetic and epigenetic alterations in pancreatic carcinogenesis.
Author: Delpu, Yannick|Hanoun, Naima|Lulka, Hubert|Sicard, Flavie|Selves, Janick|Buscail, Louis|Torrisani, Jerome|Cordelier, Pierre
PMID: 21886451
Journal: Cancer Epidemiol. 2011 Dec;35(6):e116-20.
Title: Clinical features predicting identification of CDKN2A mutations in Italian patients with familial cutaneous melanoma.
Author: Pedace, Lucia|De Simone, Paola|Castori, Marco|Sperduti, Isabella|Silipo, Vitaliano|Eibenschutz, Laura|De Bernardo, Carmelilia|Buccini, Pierluigi|Moscarella, Elvira|Panetta, Chiara|Ferrari, Angela|Grammatico, Paola|Catricala, Caterina
PMID: 21893440
Journal: JOP. 2011 Sep 9;12(5):464-8.
Title: A minute pancreatic ductal adenocarcinoma with lipomatous pseudohypertrophy of the pancreas.
Author: Izumi, Sadanobu|Nakamura, Satoko|Tokumo, Masaki|Mano, Shohei
PMID: 21904072
Journal: Oncotarget. 2011 Nov;2(11):862-73.
Title: Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo.
Author: Qiu, Wanglong|Sahin, Fikret|Iacobuzio-Donahue, Christine A|Garcia-Carracedo, Dario|Wang, Wendy M|Kuo, Chia-Yu|Chen, Doris|Arking, Dan E|Lowy, Andrew M|Hruban, Ralph H|Remotti, Helen E|Su, Gloria H
PMID: 22113502
Journal: Oncology. 2011;81(3-4):259-72.
Title: Molecular pathogenesis of pancreatic cancer and clinical perspectives.
Author: Matthaios, D|Zarogoulidis, P|Balgouranidou, I|Chatzaki, E|Kakolyris, S
PMID: 22116519
Journal: Oncol Lett. 2011 Jan;2(1):161-166.
Title: Ductal adenocarcinoma of the pancreas: Expression of growth factor receptors, oncogenes and suppressor genes, and their relationship to pathological features, staging and survival.
Author: Lozano-Leon, Antonio|Perez-Quintela, Begona Vieites|Iglesias-Garcia, Julio|Larino-Noia, Jose|Varo, Evaristo|Forteza, Jeronimo|Dominguez-Munoz, J Enrique
PMID: 22870146
Journal: Cancers (Basel). 2011 Feb 9;3(1):582-602.
Title: Experimental animal models of pancreatic carcinogenesis for prevention studies and their relevance to human disease.
Author: Takahashi, Mami|Hori, Mika|Mutoh, Michihiro|Wakabayashi, Keiji|Nakagama, Hitoshi
PMID: 24212630
Journal: Dig Liver Dis. 2012 May;44(5):442-6.
Title: Familial intraductal papillary mucinous neoplasms of the pancreas.
Author: Rebours, Vinciane|Couvelard, Anne|Peyroux, Jean-Luc|Sauvanet, Alain|Hammel, Pascal|Ruszniewski, Philippe|Levy, Philippe
PMID: 21824831
Journal: Oncogene. 2012 May 17;31(20):2535-44.
Title: A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
Author: Whipple, C A|Young, A L|Korc, M
PMID: 21996748
Journal: Scand J Immunol. 2012 Mar;75(3):342-9.
Title: Immunodiagnostic value of combined detection of autoantibodies to tumor-associated antigens as biomarkers in pancreatic cancer.
Author: Li, J|Wang, L J|Ying, X|Han, S X|Bai, E|Zhang, Y|Zhu, Q
PMID: 22010875
Journal: J Gastroenterol. 2012 Feb;47(2):203-13.
Title: Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression.
Author: Mohri, Dai|Asaoka, Yoshinari|Ijichi, Hideaki|Miyabayashi, Koji|Kudo, Yotaro|Seto, Motoko|Ohta, Miki|Tada, Motohisa|Tanaka, Yasuo|Ikenoue, Tsuneo|Tateishi, Keisuke|Isayama, Hiroyuki|Kanai, Fumihiko|Fukushima, Noriyoshi|Tada, Minoru|Kawabe, Takao|Omata, Mas
PMID: 22041919
Journal: FASEB J. 2012 Feb;26(2):938-46.
Title: Loss of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells.
Author: Kemmner, Wolfgang|Kessel, Pia|Sanchez-Ruderisch, Hugo|Moller, Heinz|Hinderlich, Stephan|Schlag, Peter M|Detjen, Katharina
PMID: 22049060
Journal: Cancer Sci. 2012 Feb;103(2):169-75.
Title: Tumor suppressor p16INK4a controls oncogenic K-Ras function in human pancreatic cancer cells.
Author: Rabien, Anja|Sanchez-Ruderisch, Hugo|Schulz, Petra|Otto, Noreen|Wimmel, Anja|Wiedenmann, Bertram|Detjen, Katharina M
PMID: 22049925
Journal: J Gastrointest Surg. 2012 Jan;16(1):104-12; discussion 112.
Title: RAGE gene deletion inhibits the development and progression of ductal neoplasia and prolongs survival in a murine model of pancreatic cancer.
Author: DiNorcia, Joseph|Lee, Minna K|Moroziewicz, Dorota N|Winner, Megan|Suman, Paritosh|Bao, Fei|Remotti, Helen E|Zou, Yu Shan|Yan, Shi Fang|Qiu, Wanglong|Su, Gloria H|Schmidt, Ann Marie|Allendorf, John D
PMID: 22052106
Journal: Cancer Lett. 2012 May 1;318(1):99-105.
Title: Targeted silencing of TRPM7 ion channel induces replicative senescence and produces enhanced cytotoxicity with gemcitabine in pancreatic adenocarcinoma.
Author: Yee, Nelson S|Zhou, Weiqiang|Lee, Minsun|Yee, Rosemary K
PMID: 22166235
Journal: Curr Mol Med. 2012 Mar;12(3):331-41.
Title: Genomic sequencing of key genes in mouse pancreatic cancer cells.
Author: Wang, Y|Zhang, Y|Yang, J|Ni, X|Liu, S|Li, Z|Hodges, S E|Fisher, W E|Brunicardi, F C|Gibbs, R A|Gingras, M-C|Li, M
PMID: 22208613
Journal: J Cell Physiol. 2012 Oct;227(10):3373-80.
Title: Inactivation of Ink4a/Arf leads to deregulated expression of miRNAs in K-Ras transgenic mouse model of pancreatic cancer.
Author: Ali, Shadan|Banerjee, Sanjeev|Logna, Farah|Bao, Bin|Philip, Philip A|Korc, Murray|Sarkar, Fazlul H
PMID: 22213426
Journal: Mol Med Rep. 2012 Apr;5(4):1106-10.
Title: Reduced levels of p15INK4b, p16INK4a, p21cip1 and p27kip1 in pancreatic carcinoma.
Author: Li, Gang|Ji, Yuan|Liu, Chen|Li, JingQi|Zhou, YingQi
PMID: 22293850
Journal: J Med Genet. 2012 Mar;49(3):164-70.
Title: CDKN2A is the main susceptibility gene in Italian pancreatic cancer families.
Author: Ghiorzo, Paola|Fornarini, Giuseppe|Sciallero, Stefania|Battistuzzi, Linda|Belli, Fiorenza|Bernard, Loris|Bonelli, Luigina|Borgonovo, Giacomo|Bruno, William|De Cian, Franco|Decensi, Andrea|Filauro, Marco|Faravelli, Francesca|Gozza, Alberto|Gargiulo, Sara|M
PMID: 22368299
Journal: Scand J Surg. 2012;101(1):38-44.
Title: Preliminary study analyzing the methylated genes in the plasma of patients with pancreatic cancer.
Author: Park, J W|Baek, I H|Kim, Y T
PMID: 22414467
Journal: Clin Cancer Res. 2012 May 15;18(10):2838-49.
Title: Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients.
Author: Speisky, Daniela|Duces, Aurelie|Bieche, Ivan|Rebours, Vinciane|Hammel, Pascal|Sauvanet, Alain|Richard, Stephane|Bedossa, Pierre|Vidaud, Michel|Murat, Arnaud|Niccoli, Patricia|Scoazec, Jean-Yves|Ruszniewski, Philippe|Couvelard, Anne
PMID: 22461457
Journal: World J Gastroenterol. 2012 Mar 28;18(12):1286-94.
Title: Mouse models of pancreatic cancer.
Author: Herreros-Villanueva, Marta|Hijona, Elizabeth|Cosme, Angel|Bujanda, Luis
PMID: 22493542
Journal: J Natl Cancer Inst. 2012 Jun 20;104(12):953-6.
Title: Risk of non-melanoma cancers in first-degree relatives of CDKN2A mutation carriers.
Author: Mukherjee, Bhramar|Delancey, John Oliver|Raskin, Leon|Everett, Jessica|Jeter, Joanne|Begg, Colin B|Orlow, Irene|Berwick, Marianne|Armstrong, Bruce K|Kricker, Anne|Marrett, Loraine D|Millikan, Robert C|Culver, Hoda Anton|Rosso, Stefano|Zanetti, Roberto|Kan
PMID: 22534780
Journal: PLoS One. 2012;7(5):e37509.
Title: Whole blood DNA aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease: a pilot study.
Author: Dauksa, Albertas|Gulbinas, Antanas|Barauskas, Giedrius|Pundzius, Juozas|Oldenburg, Johannes|El-Maarri, Osman
PMID: 22629410
Journal: J Med Genet. 2012 Jun;49(6):362-5.
Title: Indication for CDKN2A-mutation analysis in familial pancreatic cancer families without melanomas.
Author: Harinck, Femme|Kluijt, Irma|van der Stoep, Nienke|Oldenburg, Rogier A|Wagner, Anja|Aalfs, Cora M|Sijmons, Rolf H|Poley, Jan-Werner|Kuipers, Ernst J|Fockens, Paul|van Os, Theo A M|Bruno, Marco J
PMID: 22636603
Journal: Autophagy. 2012 Jun;8(6):989-91.
Title: AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway.
Author: Kang, Rui|Tang, Daolin|Lotze, Michael T|Zeh, Herbert J 3rd
PMID: 22722139
Journal: Clin Cancer Res. 2012 Dec 1;18(23):6519-30.
Title: Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity.
Author: Cui, Yunfeng|Brosnan, Jacqueline A|Blackford, Amanda L|Sur, Surojit|Hruban, Ralph H|Kinzler, Kenneth W|Vogelstein, Bert|Maitra, Anirban|Diaz, Luis A Jr|Iacobuzio-Donahue, Christine A|Eshleman, James R
PMID: 22753594
Journal: Curr Opin Gastroenterol. 2012 Sep;28(5):516-22.
Title: Emerging frontiers in pancreatic cancer research: elaboration of key genes, cells and the extracellular milieu.
Author: Kumar-Sinha, Chandan|Wei, Iris|Simeone, Diane M
PMID: 22759592
Journal: J Am Acad Dermatol. 2012 Dec;67(6):1257-64.
Title: Familial melanoma: clinical factors associated with germline CDKN2A mutations according to the number of patients affected by melanoma in a family.
Author: Maubec, Eve|Chaudru, Valerie|Mohamdi, Hamida|Blondel, Christophe|Margaritte-Jeannin, Patricia|Forget, Sebastien|Corda, Eve|Boitier, Francoise|Dalle, Stephane|Vabres, Pierre|Perrot, Jean-Luc|Lyonnet, Dominique Stoppa|Zattara, Helene|Mansard, Sandrine|Grang
PMID: 22841127
Journal: Cancer J. 2012 Jul-Aug;18(4):350-4.
Title: Genetic testing by cancer site: pancreas.
Author: Axilbund, Jennifer E|Wiley, Elizabeth A
PMID: 22846737
Journal: PLoS One. 2012;7(7):e42234.
Title: RhoT1 and Smad4 are correlated with lymph node metastasis and overall survival in pancreatic cancer.
Author: Jiang, Hua|He, Chengzhi|Geng, Shasha|Sheng, Haihui|Shen, Xiaoying|Zhang, Xiaoyan|Li, Hang|Zhu, Shizhang|Chen, Ximei|Yang, Changqing|Gao, HengJun
PMID: 22860091
Journal: Clin Cancer Res. 2012 Aug 15;18(16):4285-90.
Title: Conceptual framework for cutting the pancreatic cancer fuel supply.
Author: Le, Anne|Rajeshkumar, N V|Maitra, Anirban|Dang, Chi V
PMID: 22896695
Journal: FEBS J. 2012 Nov;279(21):4062-80.
Title: Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model.
Author: Amano, Maho|Eriksson, Hanna|Manning, Joachim C|Detjen, Katharina M|Andre, Sabine|Nishimura, Shin-Ichiro|Lehtio, Janne|Gabius, Hans-Joachim
PMID: 22943525
Journal: Cancer Cell. 2012 Sep 11;22(3):318-30.
Title: EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma.
Author: Navas, Carolina|Hernandez-Porras, Isabel|Schuhmacher, Alberto J|Sibilia, Maria|Guerra, Carmen|Barbacid, Mariano
PMID: 22975375
Journal: Clin Cancer Res. 2012 Nov 15;18(22):6339-47.
Title: Clinical significance of the genetic landscape of pancreatic cancer and implications for identification of potential long-term survivors.
Author: Yachida, Shinichi|White, Catherine M|Naito, Yoshiki|Zhong, Yi|Brosnan, Jacqueline A|Macgregor-Das, Anne M|Morgan, Richard A|Saunders, Tyler|Laheru, Daniel A|Herman, Joseph M|Hruban, Ralph H|Klein, Alison P|Jones, Sian|Velculescu, Victor|Wolfgang, Christop
PMID: 22991414
Journal: J Clin Invest. 2012 Nov;122(11):4118-29.
Title: Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans.
Author: Ochi, Atsuo|Graffeo, Christopher S|Zambirinis, Constantinos P|Rehman, Adeel|Hackman, Michael|Fallon, Nina|Barilla, Rocky M|Henning, Justin R|Jamal, Mohsin|Rao, Raghavendra|Greco, Stephanie|Deutsch, Michael|Medina-Zea, Marco V|Bin Saeed, Usama|Ego-Osuala,
PMID: 23023703
Journal: PPAR Res. 2012;2012:367450.
Title: Peroxisome proliferator-activated receptor gamma and regulations by the ubiquitin-proteasome system in pancreatic cancer.
Author: Stravodimou, Athina|Mazzoccoli, Gianluigi|Voutsadakis, Ioannis A
PMID: 23049538
Journal: Nature. 2012 Nov 15;491(7424):399-405.
Title: Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.
Author: Biankin, Andrew V|Waddell, Nicola|Kassahn, Karin S|Gingras, Marie-Claude|Muthuswamy, Lakshmi B|Johns, Amber L|Miller, David K|Wilson, Peter J|Patch, Ann-Marie|Wu, Jianmin|Chang, David K|Cowley, Mark J|Gardiner, Brooke B|Song, Sarah|Harliwong, Ivon|Idrisog
PMID: 23103869
Journal: Cancer J. 2012 Nov-Dec;18(6):485-91.
Title: Inherited pancreatic cancer syndromes.
Author: Solomon, Sheila|Das, Siddhartha|Brand, Randall|Whitcomb, David C
PMID: 23187834
Journal: Gastroenterol Res Pract. 2012;2012:243524.
Title: Molecular Biologic Approach to the Diagnosis of Pancreatic Carcinoma Using Specimens Obtained by EUS-Guided Fine Needle Aspiration.
Author: Kato, Kiyohito|Kamada, Hideki|Fujimori, Takayuki|Aritomo, Yuuichi|Ono, Masahiro|Masaki, Tsutomu
PMID: 23197977
Journal: Coll Antropol. 2012 Sep;36(3):1063-7.
Title: Etiology and oncogenesis of pancreatic carcinoma.
Author: Dobrila-Dintinjana, Renata|Vanis, Nenad|Dintinjana, Marijan|Radic, Mladen
PMID: 23213974
Journal: Adv Exp Med Biol. 2012;771:229-39.
Title: Pancreatic cancer and diabetes.
Author: Morrison, Maureen
PMID: 23393682
Journal: J Cell Physiol. 2013 Mar;228(3):556-62.
Title: Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype.
Author: Wang, Zhiwei|Ali, Shadan|Banerjee, Sanjeev|Bao, Bin|Li, Yiwei|Azmi, Asfar S|Korc, Murray|Sarkar, Fazlul H
PMID: 22806240
Journal: Anticancer Agents Med Chem. 2013 Feb;13(2):261-9.
Title: BRCA2 dysfunction promotes malignant transformation of pancreatic intraepithelial neoplasia.
Author: Wang, Qi|Liu, Hongrui|Liu, Tingting|Shu, Shizhen|Jiang, He|Cheng, Shidan|Yuan, Yaozong|Yang, Weiguo|Wang, Lifu
PMID: 22934697
Journal: Gut. 2013 Mar;62(3):339-47.
Title: International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer.
Author: Canto, Marcia Irene|Harinck, Femme|Hruban, Ralph H|Offerhaus, George Johan|Poley, Jan-Werner|Kamel, Ihab|Nio, Yung|Schulick, Richard S|Bassi, Claudio|Kluijt, Irma|Levy, Michael J|Chak, Amitabh|Fockens, Paul|Goggins, Michael|Bruno, Marco
PMID: 23135763
Journal: Curr Mol Med. 2013 Aug;13(7):1140-59.
Title: Chemoprevention gene therapy (CGT): novel combinatorial approach for preventing and treating pancreatic cancer.
Author: Sarkar, S|Azab, B M|Das, S K|Quinn, B A|Shen, X|Dash, R|Emdad, L|Thomas, S|Dasgupta, S|Su, Z-Z|Wang, X-Y|Sarkar, D|Fisher, P B
PMID: 23157679
Journal: Clin Cancer Res. 2013 Jan 15;19(2):442-9.
Title: Variation in precursor lesions of pancreatic cancer among high-risk groups.
Author: Potjer, Thomas P|Schot, Ingrid|Langer, Peter|Heverhagen, Johannes T|Wasser, Martin N J M|Slater, Emily P|Kloppel, Gunter|Morreau, Hans M|Bonsing, Bert A|de Vos Tot Nederveen Cappel, Wouter H|Bargello, Mathias|Gress, Thomas M|Vasen, Hans F A|Bartsch, Detle
PMID: 23172884
Journal: Psychooncology. 2013 Feb;22(2):276-89.
Title: Genetic testing for hereditary melanoma and pancreatic cancer: a longitudinal study of psychological outcome.
Author: Aspinwall, Lisa G|Taber, Jennifer M|Leaf, Samantha L|Kohlmann, Wendy|Leachman, Sancy A
PMID: 23382133
Journal: Gut. 2013 Sep;62(9):1364-72.
Title: Senescence in pancreatic carcinogenesis: from signalling to chromatin remodelling and epigenetics.
Author: Singh, Shiv K|Ellenrieder, Volker
PMID: 23408353
Journal: Cancer Res. 2013 Mar 15;73(6):1821-30.
Title: Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.
Author: Lin, Wan-chi|Rajbhandari, Nirakar|Liu, Chengbao|Sakamoto, Kazuhito|Zhang, Qian|Triplett, Aleata A|Batra, Surinder K|Opavsky, Rene|Felsher, Dean W|DiMaio, Dominick J|Hollingsworth, Michael A|Morris, John P 4th|Hebrok, Matthias|Witkiewicz, Agnieszka K|Brody
PMID: 23467612
Journal: World J Gastroenterol. 2013 Mar 21;19(11):1718-27.
Title: Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids.
Author: Kato, Norihiro|Yamamoto, Hiroyuki|Adachi, Yasushi|Ohashi, Hirokazu|Taniguchi, Hiroaki|Suzuki, Hiromu|Nakazawa, Mayumi|Kaneto, Hiroyuki|Sasaki, Shigeru|Imai, Kohzoh|Shinomura, Yasuhisa
PMID: 23555160
Journal: PLoS One. 2013;8(4):e60870.
Title: Somatic mutations in exocrine pancreatic tumors: association with patient survival.
Author: Rachakonda, P Sivaramakrishna|Bauer, Andrea S|Xie, Huaping|Campa, Daniele|Rizzato, Cosmeri|Canzian, Federico|Beghelli, Stefania|Greenhalf, William|Costello, Eithne|Schanne, Michaela|Heller, Anette|Scarpa, Aldo|Neoptolemos, John P|Werner, Jens|Buchler, Mar
PMID: 23565280
Journal: Am J Med Genet A. 2013 Jun;161A(6):1425-31.
Title: Multiple neurofibromas as the presenting feature of familial atypical multiple malignant melanoma (FAMMM) syndrome.
Author: Vanneste, Rachel|Smith, Erika|Graham, Gail
PMID: 23613284
Journal: Am J Pathol. 2013 Jul;183(1):296-303.
Title: FAM190A deficiency creates a cell division defect.
Author: Patel, Kalpesh|Scrimieri, Francesca|Ghosh, Soma|Zhong, Jun|Kim, Min-Sik|Ren, Yunzhao R|Morgan, Richard A|Iacobuzio-Donahue, Christine A|Pandey, Akhilesh|Kern, Scott E
PMID: 23665203
Journal: Mol Cancer Ther. 2013 Jul;12(7):1190-201.
Title: PG545, an angiogenesis and heparanase inhibitor, reduces primary tumor growth and metastasis in experimental pancreatic cancer.
Author: Ostapoff, Katherine T|Awasthi, Niranjan|Cenik, Bercin Kutluk|Hinz, Stefan|Dredge, Keith|Schwarz, Roderich E|Brekken, Rolf A
PMID: 23696215
Journal: Biochem Biophys Res Commun. 2013 Jun 28;436(2):217-22.
Title: Evidence that P12, a specific variant of P16(INK4A), plays a suppressive role in human pancreatic carcinogenesis.
Author: Poi, Ming J|Knobloch, Thomas J|Yuan, Chunhua|Tsai, Ming-Daw|Weghorst, Christopher M|Li, Junan
PMID: 23727582
Journal: Pancreas. 2013 Jul;42(5):740-59.
Title: Sweating the small stuff: microRNAs and genetic changes define pancreatic cancer.
Author: Tang, Siuwah|Bonaroti, Jillian|Unlu, Sebnem|Liang, Xiaoyan|Tang, Daolin|Zeh, Herbert J|Lotze, Michael T
PMID: 23774697
Journal: Cancer Cytopathol. 2013 Dec;121(12):688-94.
Title: Clinical next-generation sequencing successfully applied to fine-needle aspirations of pulmonary and pancreatic neoplasms.
Author: Young, Geneva|Wang, Kai|He, Jie|Otto, Geoff|Hawryluk, Matthew|Zwirco, Zac|Brennan, Tina|Nahas, Michelle|Donahue, Amy|Yelensky, Roman|Lipson, Doron|Sheehan, Christine E|Boguniewicz, Ann B|Stephens, Philip J|Miller, Vincent A|Ross, Jeffrey S
PMID: 23893923
Journal: Cancer Lett. 2013 Dec 1;341(2):195-203.
Title: Novel synthetic curcumin analogues EF31 and UBS109 are potent DNA hypomethylating agents in pancreatic cancer.
Author: Nagaraju, Ganji Purnachandra|Zhu, Shijun|Wen, Jing|Farris, Alton B|Adsay, Volkan N|Diaz, Roberto|Snyder, James P|Mamoru, Shoji|El-Rayes, Bassel F
PMID: 23933177
Journal: Cancer Prev Res (Phila). 2013 Oct;6(10):1046-55.
Title: Dietary energy balance modulation of Kras- and Ink4a/Arf+/--driven pancreatic cancer: the role of insulin-like growth factor-I.
Author: Lashinger, Laura M|Harrison, Lauren M|Rasmussen, Audrey J|Logsdon, Craig D|Fischer, Susan M|McArthur, Mark J|Hursting, Stephen D
PMID: 23980075
Journal: BMC Genomics. 2013 Sep 16;14:624.
Title: Integrative genomic and functional profiling of the pancreatic cancer genome.
Author: Shain, A Hunter|Salari, Keyan|Giacomini, Craig P|Pollack, Jonathan R
PMID: 24041470
Journal: Pathologe. 2013 Nov;34 Suppl 2:214-20.
Title: [Will molecular diagnostics become established in pancreatic pathology?].
Author: Sipos, B|Sperveslage, J
PMID: 24196616
Journal: J Clin Invest. 2013 Nov;123(11):4681-94.
Title: Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression.
Author: Court, Helen|Amoyel, Marc|Hackman, Michael|Lee, Kyoung Eun|Xu, Ruliang|Miller, George|Bar-Sagi, Dafna|Bach, Erika A|Bergo, Martin O|Philips, Mark R
PMID: 24216479
Journal: Med Sci (Paris). 2013 Nov;29(11):991-7.
Title: [Kras oncogene and pancreatic cancer: thirty years after].
Author: Bournet, Barbara|Dufresne, Marlene|Selves, Janick|Torrisani, Jerome|Cordelier, Pierre|Buscail, Louis
PMID: 24280502
Journal: Front Physiol. 2014 Jan 16;4:415.
Title: Risk factors for pancreatic cancer: underlying mechanisms and potential targets.
Author: Kolodecik, Thomas|Shugrue, Christine|Ashat, Munish|Thrower, Edwin C
PMID: 24474939
Journal: Oncogene. 2014 Feb 13;33(7):823-31.
Title: Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.
Author: Ray, K C|Moss, M E|Franklin, J L|Weaver, C J|Higginbotham, J|Song, Y|Revetta, F L|Blaine, S A|Bridges, L R|Guess, K E|Coffey, R J|Crawford, H C|Washington, M K|Means, A L
PMID: 23376846
Journal: Gut. 2014 Jun;63(6):984-95.
Title: Genetic inactivation of Nupr1 acts as a dominant suppressor event in a two-hit model of pancreatic carcinogenesis.
Author: Cano, Carla E|Hamidi, Tewfik|Garcia, Maria Noe|Grasso, Daniel|Loncle, Celine|Garcia, Stephane|Calvo, Ezequiel|Lomberk, Gwen|Dusetti, Nelson|Bartholin, Laurent|Urrutia, Raul|Iovanna, Juan L
PMID: 24026351
Journal: Genes Dev. 2014 Jan 1;28(1):1-7.
Title: Familial pancreatic cancer: genetic advances.
Author: Rustgi, Anil K
PMID: 24395243
Journal: Am J Clin Pathol. 2014 Feb;141(2):168-80.
Title: Molecular genetics of pancreatic neoplasms and their morphologic correlates: an update on recent advances and potential diagnostic applications.
Author: Reid, Michelle D|Saka, Burcu|Balci, Serdar|Goldblum, Andrew S|Adsay, N Volkan
PMID: 24436263
Journal: Cancer J. 2014 Jan-Feb;20(1):80-4.
Title: Genetic progression of pancreatic cancer.
Author: Cowan, Robert W|Maitra, Anirban
PMID: 24445769
Journal: Pathol Int. 2014 Jan;64(1):10-9.
Title: Molecular pathology of pancreatic cancer.
Author: Saiki, Yuriko|Horii, Akira
PMID: 24471965
Journal: Discov Med. 2014 Feb;17(92):67-73.
Title: Epigenetic changes associated with neoplasms of the exocrine and endocrine pancreas.
Author: Guo, Mingzhou|Jia, Yan|Yu, Zhengtao|House, Michael G|Esteller, Manel|Brock, Malcolm V|Herman, James G
PMID: 24534469
Journal: Int J Toxicol. 2014 Mar-Apr;33(2):116-29.
Title: Mitochondrial oxidative stress-induced epigenetic modifications in pancreatic epithelial cells.
Author: Mishra, Pradyumna Kumar|Raghuram, Gorantla Venkata|Jain, Deepika|Jain, Subodh Kumar|Khare, Naveen Kumar|Pathak, Neelam
PMID: 24563415
Journal: J Pathol. 2014 Jul;233(3):217-27.
Title: Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas.
Author: Amato, Eliana|Molin, Marco Dal|Mafficini, Andrea|Yu, Jun|Malleo, Giuseppe|Rusev, Borislav|Fassan, Matteo|Antonello, Davide|Sadakari, Yoshihiko|Castelli, Paola|Zamboni, Giuseppe|Maitra, Anirban|Salvia, Roberto|Hruban, Ralph H|Bassi, Claudio|Capelli, Paola|
PMID: 24604757
Journal: J Cell Physiol. 2014 Oct;229(10):1437-43.
Title: Pancreatic cancer-induced cachexia is Jak2-dependent in mice.
Author: Gilabert, Marine|Calvo, Ezequiel|Airoldi, Ana|Hamidi, Tewfik|Moutardier, Vincent|Turrini, Olivier|Iovanna, Juan
PMID: 24648112
Journal: Curr Treat Options Oncol. 2014 Jun;15(2):336-50.
Title: Clinical applications of melanoma genetics.
Author: Gabree, Michele|Patel, Devanshi|Rodgers, Linda
PMID: 24652319
Journal: J Gastrointest Cancer. 2014 Sep;45(3):256-61.
Title: Familial pancreatic cancer: challenging diagnostic approach and therapeutic management.
Author: Mastoraki, Aikaterini|Chatzimavridou-Grigoriadou, Victoria|Chatzipetrou, Varvara|Mastoraki, Sotiria|Papanikolaou, Ioannis S|Danias, Nikolaos|Smyrniotis, Vasilios|Arkadopoulos, Nikolaos
PMID: 24756831
Journal: Mol Oncol. 2014 Oct;8(7):1253-65.
Title: Mesenchymal-like pancreatic cancer cells harbor specific genomic alterations more frequently than their epithelial-like counterparts.
Author: Sinha, Arkadeep|Cherba, David|Bartlam, Heather|Lenkiewicz, Elizabeth|Evers, Lisa|Barrett, Michael T|Haab, Brian B
PMID: 24837184
Journal: Cancer Lett. 2014 Aug 28;351(1):134-42.
Title: Deregulation of miR-146a expression in a mouse model of pancreatic cancer affecting EGFR signaling.
Author: Ali, Shadan|Ahmad, Aamir|Aboukameel, Amro|Ahmed, Alia|Bao, Bin|Banerjee, Sanjeev|Philip, Philip A|Sarkar, Fazlul H
PMID: 24839931
Journal: J Med Genet. 2014 Aug;51(8):545-52.
Title: High risk of tobacco-related cancers in CDKN2A mutation-positive melanoma families.
Author: Helgadottir, Hildur|Hoiom, Veronica|Jonsson, Goran|Tuominen, Rainer|Ingvar, Christian|Borg, Ake|Olsson, Hakan|Hansson, Johan
PMID: 24935963
Journal: World J Gastroenterol. 2014 Jun 28;20(24):7830-48.
Title: Epigenetics and pancreatic cancer: pathophysiology and novel treatment aspects.
Author: Neureiter, Daniel|Jager, Tarkan|Ocker, Matthias|Kiesslich, Tobias
PMID: 24976721
Journal: Exp Mol Pathol. 2014 Aug;97(1):144-7.
Title: Association of melanoma with intraepithelial neoplasia of the pancreas in three patients.
Author: Fidalgo, Felipe|Gomes, Elimar Elias|Moredo Facure, Luciana|Da Silva, Felipe Carneiro|Carraro, Dirce Maria|de Sa, Bianca Costa Soares|Duprat Neto, Joao Pedreira|Krepischi, Ana Cristina Victorino
PMID: 24984283
Journal: Pancreas. 2014 Oct;43(7):1009-13.
Title: Deletions of RDINK4/ARF enhancer in gastrinomas and nonfunctioning pancreatic neuroendocrine tumors.
Author: Poi, Ming J|Drosdeck, Joe|Frankel, Wendy L|Muscarella, Peter|Li, Junan
PMID: 25003221
Journal: J Am Acad Dermatol. 2014 Nov;71(5):888-95.
Title: Increased prevalence of lung, breast, and pancreatic cancers in addition to melanoma risk in families bearing the cyclin-dependent kinase inhibitor 2A mutation: implications for genetic counseling.
Author: Potrony, Miriam|Puig-Butille, Joan Anton|Aguilera, Paula|Badenas, Celia|Carrera, Cristina|Malvehy, Josep|Puig, Susana
PMID: 25064638
Journal: World J Gastroenterol. 2014 Aug 21;20(31):10825-44.
Title: Novel therapeutic targets for pancreatic cancer.
Author: Tang, Shing-Chun|Chen, Yang-Chao
PMID: 25152585
Journal: Oncotarget. 2014 Aug 15;5(15):6512-25.
Title: CDK4/6 inhibitors have potent activity in combination with pathway selective therapeutic agents in models of pancreatic cancer.
Author: Franco, Jorge|Witkiewicz, Agnieszka K|Knudsen, Erik S
PMID: 25156567
Journal: Carcinogenesis. 2014 Dec;35(12):2698-705.
Title: Genetic polymorphisms in the 9p21 region associated with risk of multiple cancers.
Author: Li, Wen-Qing|Pfeiffer, Ruth M|Hyland, Paula L|Shi, Jianxin|Gu, Fangyi|Wang, Zhaoming|Bhattacharjee, Samsiddhi|Luo, Jun|Xiong, Xiaoqin|Yeager, Meredith|Deng, Xiang|Hu, Nan|Taylor, Philip R|Albanes, Demetrius|Caporaso, Neil E|Gapstur, Susan M|Amundadottir,
PMID: 25239644
Journal: Genes Cancer. 2014 Sep;5(9-10):337-47.
Title: Mirk kinase inhibition blocks the in vivo growth of pancreatic cancer cells.
Author: Deng, Xiaobing|Friedman, Eileen
PMID: 25352950
Journal: Semin Diagn Pathol. 2014 Nov;31(6):491-7.
Title: Pathology and genetics of pancreatic neoplasms with acinar differentiation.
Author: Wood, Laura D|Klimstra, David S
PMID: 25441307
Journal: Int J Biochem Cell Biol. 2014 Dec;57:142-8.
Title: Arrested development and the great escape--the role of cellular senescence in pancreatic cancer.
Author: Moir, John A G|White, Steven A|Mann, Jelena
PMID: 25461770
Journal: Cell Cycle. 2014;13(18):2962-74.
Title: Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway.
Author: Lv, Hongjun|Liu, Rui|Fu, Jiao|Yang, Qi|Shi, Jing|Chen, Pu|Ji, Meiju|Shi, Bingyin|Hou, Peng
PMID: 25486483
Journal: Eksp Klin Gastroenterol. 2014;(10):70-6.
Title: [Genetic aspects of pancreatic cancer].
Author: Grigor'eva, I N|Efimova, O V|Suvorova, T S|Tov, N L
PMID: 25911935
Journal: Oncotarget. 2015 Mar 10;6(7):4553-61.
Title: Molecular landscape of pancreatic cancer: implications for current clinical trials.
Author: Heestand, Gregory M|Kurzrock, Razelle
PMID: 11051691
Journal: Eur J Hum Genet. 2015 May;23(5):711-4.
Title: Prospective risk of cancer and the influence of tobacco use in carriers of the p16-Leiden germline variant.
Author: Potjer, Thomas P|Kranenburg, Heidi E|Bergman, Wilma|de Vos tot Nederveen Cappel, Wouter H|van Monsjou, Hester S|Barge-Schaapveld, Daniela Q C M|Vasen, Hans F A
PMID: 25227142
Journal: Fam Cancer. 2015 Mar;14(1):95-103.
Title: Familial and sporadic pancreatic cancer share the same molecular pathogenesis.
Author: Norris, Alexis L|Roberts, Nicholas J|Jones, Sian|Wheelan, Sarah J|Papadopoulos, Nickolas|Vogelstein, Bert|Kinzler, Kenneth W|Hruban, Ralph H|Klein, Alison P|Eshleman, James R
PMID: 25240578
Journal: Radiology. 2015 Mar;274(3):790-9.
Title: Vascular endothelial growth factor receptor type 2-targeted contrast-enhanced US of pancreatic cancer neovasculature in a genetically engineered mouse model: potential for earlier detection.
Author: Pysz, Marybeth A|Machtaler, Steven B|Seeley, E Scott|Lee, John J|Brentnall, Teresa A|Rosenberg, Jarrett|Tranquart, Francois|Willmann, Jurgen K
PMID: 25322341
Journal: Mol Med Rep. 2015 Jan;11(1):277-82.
Title: Identification of dysregulated pathways associated with pancreatic cancer by survival analysis.
Author: Yuan, Qiong-Ying|Gu, Yan-Ping|Wang, Cong-Jun|Zhang, Hui|Wang, Xing-Peng
PMID: 25333741
Journal: Genet Med. 2015 Jul;17(7):569-77.
Title: BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study.
Author: Zhen, David B|Rabe, Kari G|Gallinger, Steven|Syngal, Sapna|Schwartz, Ann G|Goggins, Michael G|Hruban, Ralph H|Cote, Michele L|McWilliams, Robert R|Roberts, Nicholas J|Cannon-Albright, Lisa A|Li, Donghui|Moyes, Kelsey|Wenstrup, Richard J|Hartman, Anne-Rene
PMID: 25356972
Journal: Adv Drug Deliv Rev. 2015 Jan;81:16-33.
Title: Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer.
Author: Rachagani, Satyanarayana|Macha, Muzafar A|Heimann, Nicholas|Seshacharyulu, Parthasarathy|Haridas, Dhanya|Chugh, Seema|Batra, Surinder K
PMID: 25453266
Journal: Gastroenterology. 2015 Mar;148(3):556-64.
Title: Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer.
Author: Grant, Robert C|Selander, Iris|Connor, Ashton A|Selvarajah, Shamini|Borgida, Ayelet|Briollais, Laurent|Petersen, Gloria M|Lerner-Ellis, Jordan|Holter, Spring|Gallinger, Steven
PMID: 25479140
Journal: J Surg Res. 2015 Mar;194(1):212-9.
Title: High-risk population in sporadic pancreatic adenocarcinoma: guidelines for screening.
Author: Bruenderman, Elizabeth H|Martin, Robert C G 2nd
PMID: 25479908
Journal: Nat Genet. 2015 Jan;47(1):47-56.
Title: A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.
Author: Rad, Roland|Rad, Lena|Wang, Wei|Strong, Alexander|Ponstingl, Hannes|Bronner, Iraad F|Mayho, Matthew|Steiger, Katja|Weber, Julia|Hieber, Maren|Veltkamp, Christian|Eser, Stefan|Geumann, Ulf|Ollinger, Rupert|Zukowska, Magdalena|Barenboim, Maxim|Maresch, Roma
PMID: 25485836
Journal: Ann Dermatol Venereol. 2015 Jan;142(1):26-36.
Title: [Recommendations for genetic testing and management of individuals genetically at-risk of cutaneous melanoma].
Author: Avril, M-F|Bahadoran, P|Cabaret, O|Caron, O|de la Fouchardiere, A|Demenais, F|Desjardins, L|Frebourg, T|Hammel, P|Leccia, M-T|Lesueur, F|Mahe, E|Martin, L|Maubec, E|Remenieras, A|Richard, S|Robert, C|Soufir, N|Stoppa-Lyonnet, D|Thomas, L|Vabres, P|Bressac
PMID: 25600792
Journal: Clin Cancer Res. 2015 Apr 15;21(8):1944-50.
Title: Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis.
Author: Dal Molin, Marco|Zhang, Ming|de Wilde, Roeland F|Ottenhof, Niki A|Rezaee, Neda|Wolfgang, Christopher L|Blackford, Amanda|Vogelstein, Bert|Kinzler, Kenneth W|Papadopoulos, Nickolas|Hruban, Ralph H|Maitra, Anirban|Wood, Laura D
PMID: 25623214
Journal: J Clin Pathol. 2015 Apr;68(4):283-7.
Title: A multistep cytological approach for patients with jaundice and biliary strictures of indeterminate origin.
Author: Boldorini, Renzo|Paganotti, Alessia|Andorno, Silvano|Orlando, Stefania|Mercalli, Francesca|Orsello, Marco|Ballare, Marco|Magnani, Corrado|Sartori, Massimo
PMID: 25681513
Journal: Cancer Lett. 2015 May 1;360(2):227-33.
Title: Metabolic tumor burden is associated with major oncogenomic alterations and serum tumor markers in patients with resected pancreatic cancer.
Author: Shi, Si|Ji, Shunrong|Qin, Yi|Xu, Jin|Zhang, Bo|Xu, Wenyan|Liu, Jiang|Long, Jiang|Liu, Chen|Liu, Liang|Ni, Quanxing|Yu, Xianjun
PMID: 25687883
Journal: Oncotarget. 2015 Mar 10;6(7):4553-61.
Title: Molecular landscape of pancreatic cancer: implications for current clinical trials.
Author: Heestand, Gregory M|Kurzrock, Razelle
PMID: 25714017
Journal: Nature. 2015 Feb 26;518(7540):495-501.
Title: Whole genomes redefine the mutational landscape of pancreatic cancer.
Author: Waddell, Nicola|Pajic, Marina|Patch, Ann-Marie|Chang, David K|Kassahn, Karin S|Bailey, Peter|Johns, Amber L|Miller, David|Nones, Katia|Quek, Kelly|Quinn, Michael C J|Robertson, Alan J|Fadlullah, Muhammad Z H|Bruxner, Tim J C|Christ, Angelika N|Harliwong,
PMID: 25719666
Journal: Mol Cancer Res. 2015 May;13(5):863-9.
Title: Detection of Tumor Suppressor Genes in Cancer Development by a Novel shRNA-Based Method.
Author: von Burstin, Johannes|Diersch, Sandra|Schneider, Gunter|Reichert, Maximilian|Rustgi, Anil K|Schmid, Roland M
PMID: 25724428
Journal: Semin Oncol. 2015 Feb;42(1):177-87.
Title: Novel targets in pancreatic cancer research.
Author: Kozak, Geoffrey|Blanco, Fernando F|Brody, Jonathan R
PMID: 25726061
Journal: JAMA Surg. 2015 Jun;150(6):512-8.
Title: Short-term Results of a Magnetic Resonance Imaging-Based Swedish Screening Program for Individuals at Risk for Pancreatic Cancer.
Author: Del Chiaro, Marco|Verbeke, Caroline S|Kartalis, Nikolaos|Pozzi Mucelli, Raffaella|Gustafsson, Peter|Hansson, Johan|Haas, Stephan L|Segersvard, Ralf|Andren-Sandberg, Ake|Lohr, J-Matthias
PMID: 25853369
Journal: Hepatobiliary Pancreat Dis Int. 2015 Apr;14(2):208-14.
Title: Mutations in the p16 gene in DMBA-induced pancreatic intraepithelial neoplasia and pancreatic cancer in rats.
Author: Zhu, Zhu|Liu, Tao|Han, Fei|Zhan, Su-Dong|Wang, Chun-You
PMID: 25865695
Journal: Oncol Rep. 2015 Jun;33(6):3015-23.
Title: Effects of emodin on the demethylation of tumor-suppressor genes in pancreatic cancer PANC-1 cells.
Author: Zhang, Hao|Chen, Liang|Bu, He-Qi|Yu, Qing-Jiang|Jiang, Dan-Dan|Pan, Feng-Ping|Wang, Yu|Liu, Dian-Lei|Lin, Sheng-Zhang
PMID: 25891176
Journal: Carcinogenesis. 2015 Jul;36(7):730-8.
Title: Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.
Author: Bednar, Filip|Schofield, Heather K|Collins, Meredith A|Yan, Wei|Zhang, Yaqing|Shyam, Nikhil|Eberle, Jaime A|Almada, Luciana L|Olive, Kenneth P|Bardeesy, Nabeel|Fernandez-Zapico, Martin E|Nakada, Daisuke|Simeone, Diane M|Morrison, Sean J|Pasca di Magliano,
PMID: 25939753
Journal: Am J Surg. 2015 Sep;210(3):409-16.
Title: A cost analysis of a pancreatic cancer screening protocol in high-risk populations.
Author: Bruenderman, Elizabeth|Martin, Robert C G 2nd
PMID: 26003200
Journal: Genes Chromosomes Cancer. 2015 Aug;54(8):472-481.
Title: Transflip mutations produce deletions in pancreatic cancer.
Author: Norris, Alexis L|Kamiyama, Hirohiko|Makohon-Moore, Alvin|Pallavajjala, Aparna|Morsberger, Laura A|Lee, Kurt|Batista, Denise|Iacobuzio-Donahue, Christine A|Lin, Ming-Tseh|Klein, Alison P|Hruban, Ralph H|Wheelan, Sarah J|Eshleman, James R
PMID: 26031834
Journal: Nat Genet. 2015 Aug;47(8):911-6.
Title: Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
Author: Childs, Erica J|Mocci, Evelina|Campa, Daniele|Bracci, Paige M|Gallinger, Steven|Goggins, Michael|Li, Donghui|Neale, Rachel E|Olson, Sara H|Scelo, Ghislaine|Amundadottir, Laufey T|Bamlet, William R|Bijlsma, Maarten F|Blackford, Amanda|Borges, Michael|Brenn
PMID: 26098869
Journal: BMC Res Notes. 2015 Jun 26;8:264.
Title: Pancreatic cancer-associated gene polymorphisms in a nation-wide cohort of p16-Leiden germline mutation carriers; a case-control study.
Author: Potjer, Thomas P|van der Stoep, Nienke|Houwing-Duistermaat, Jeanine J|Konings, Ingrid C A W|Aalfs, Cora M|van den Akker, Peter C|Ausems, Margreet G|Dommering, Charlotte J|van der Kolk, Lizet E|Maiburg, Merel C|Spruijt, Liesbeth|Wagner, Anja|Vasen, Hans F
PMID: 26111702
Journal: Bull Cancer. 2015 Jun;102(6 Suppl 1):S53-61.
Title: [Advance in the biology of pancreatic of cancer].
Author: Buscail, Louis|Bournet, Barbara|Dufresne, Marlene|Torrisani, Jerome|Cordelier, Pierre
PMID: 26118878
Journal: Oncotarget. 2015 Jun 30;6(18):15788-801.
Title: Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer.
Author: Witkiewicz, Agnieszka K|Borja, Nicholas A|Franco, Jorge|Brody, Jonathan R|Yeo, Charles J|Mansour, John|Choti, Michael A|McCue, Peter|Knudsen, Erik S
PMID: 26158861
Journal: Pancreas. 2015 Aug;44(6):988-94.
Title: Malignant Solitary Fibrous Tumor of the Pancreas.
Author: Estrella, Jeannelyn S|Wang, Huamin|Bhosale, Priya R|Evans, Harry L|Abraham, Susan C
PMID: 26166470
Journal: Hematol Oncol Clin North Am. 2015 Aug;29(4):641-53.
Title: Familial Pancreatic Adenocarcinoma.
Author: Petersen, Gloria M
PMID: 26226902
Journal: World J Gastrointest Endosc. 2015 Jul 25;7(9):833-42.
Title: Methods and outcomes of screening for pancreatic adenocarcinoma in high-risk individuals.
Author: Capurso, Gabriele|Signoretti, Marianna|Valente, Roberto|Arnelo, Urban|Lohr, Matthias|Poley, Jan-Werner|Delle Fave, Gianfranco|Del Chiaro, Marco
PMID: 26240684
Journal: Gastroenterology. 2015 Nov;149(6):1501-10.
Title: A combination of molecular markers and clinical features improve the classification of pancreatic cysts.
Author: Springer, Simeon|Wang, Yuxuan|Dal Molin, Marco|Masica, David L|Jiao, Yuchen|Kinde, Isaac|Blackford, Amanda|Raman, Siva P|Wolfgang, Christopher L|Tomita, Tyler|Niknafs, Noushin|Douville, Christopher|Ptak, Janine|Dobbyn, Lisa|Allen, Peter J|Klimstra, David
PMID: 26253305
Journal: Sci Rep. 2015 Sep 4;5:13563.
Title: Clinicopathological Significance of CDKN2A Promoter Hypermethylation Frequency with Pancreatic Cancer.
Author: Tang, Bo|Li, Yang|Qi, Guangying|Yuan, Shengguang|Wang, Zhenran|Yu, Shuiping|Li, Bo|He, Songqing
PMID: 26338139
Journal: Cancer. 2015 Dec 15;121(24):4382-8.
Title: Identification of germline genetic mutations in patients with pancreatic cancer.
Author: Salo-Mullen, Erin E|O'Reilly, Eileen M|Kelsen, David P|Ashraf, Asad M|Lowery, Maeve A|Yu, Kenneth H|Reidy, Diane L|Epstein, Andrew S|Lincoln, Anne|Saldia, Amethyst|Jacobs, Lauren M|Rau-Murthy, Rohini|Zhang, Liying|Kurtz, Robert C|Saltz, Leonard|Offit, Ken
PMID: 26440929
Journal: Cancer Res. 2015 Nov 15;75(22):4884-94.
Title: A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution.
Author: Walsh, Kyle M|de Smith, Adam J|Hansen, Helen M|Smirnov, Ivan V|Gonseth, Semira|Endicott, Alyson A|Xiao, Jianqiao|Rice, Terri|Fu, Cecilia H|McCoy, Lucie S|Lachance, Daniel H|Eckel-Passow, Jeanette E|Wiencke, John K|Jenkins, Robert B|Wrensch, Margaret R|Ma,
PMID: 26527286
Journal: J Clin Oncol. 2015 Dec 20;33(36):4284-92.
Title: Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer.
Author: Catenacci, Daniel V T|Junttila, Melissa R|Karrison, Theodore|Bahary, Nathan|Horiba, Margit N|Nattam, Sreenivasa R|Marsh, Robert|Wallace, James|Kozloff, Mark|Rajdev, Lakshmi|Cohen, Deirdre|Wade, James|Sleckman, Bethany|Lenz, Heinz-Josef|Stiff, Patrick|Kuma
PMID: 26527777
Journal: Sci Rep. 2015 Dec 16;5:18425.
Title: Clinical utility of circulating tumor DNA for molecular assessment in pancreatic cancer.
Author: Takai, Erina|Totoki, Yasushi|Nakamura, Hiromi|Morizane, Chigusa|Nara, Satoshi|Hama, Natsuko|Suzuki, Masami|Furukawa, Eisaku|Kato, Mamoru|Hayashi, Hideyuki|Kohno, Takashi|Ueno, Hideki|Shimada, Kazuaki|Okusaka, Takuji|Nakagama, Hitoshi|Shibata, Tatsuhiro|Ya
PMID: 26669280
Journal: Melanoma Manag. 2015 Feb;2(1):83-89.
Title: Familial risk of melanoma and links with other cancers.
Author: Lee, Kachiu C|Higgins, H William 2nd|Qureshi, Abrar A
PMID: 30190834
Journal: Anticancer Agents Med Chem. 2016;16(6):771-80.
Title: Multiple Pharmacological Properties of a Novel Parthenin Analog P16 as Evident by its Cytostatic and Antiangiogenic Potential Against Pancreatic Adenocarcinoma PANC -1 Cells.
Author: Goswami, Akshra|Shah, Bhahwal Ali|Batra, Navneet|Kumar, Ajay|Guru, Santosh Kumar|Bhushan, Shashi|Malik, Fayaz Ahmad|Joshi, Amit|Singh, Jagtar
PMID: 26299660
Journal: J Med Genet. 2016 Jan;53(1):1-14.
Title: Melanoma genetics.
Author: Read, Jazlyn|Wadt, Karin A W|Hayward, Nicholas K
PMID: 26337759
Journal: Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):27-38.
Title: RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.
Author: Fang, Bingliang
PMID: 26350096
Journal: Gastroenterology. 2016 Jan;150(1):218-228.e12.
Title: Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.
Author: Qiu, Wanglong|Tang, Sophia M|Lee, Sohyae|Turk, Andrew T|Sireci, Anthony N|Qiu, Anne|Rose, Christian|Xie, Chuangao|Kitajewski, Jan|Wen, Hui-Ju|Crawford, Howard C|Sims, Peter A|Hruban, Ralph H|Remotti, Helen E|Su, Gloria H
PMID: 26408346
Journal: Gene. 2016 Jan 15;576(1 Pt 3):476-82.
Title: Ferulic acid decreases cell viability and colony formation while inhibiting migration of MIA PaCa-2 human pancreatic cancer cells in vitro.
Author: Fahrioglu, Umut|Dodurga, Yavuz|Elmas, Levent|Secme, Mucahit
PMID: 26516023
Journal: Hum Pathol. 2016 Feb;48:117-21.
Title: Mutational spectrum of intraepithelial neoplasia in pancreatic heterotopia.
Author: Ma, Changqing|Gocke, Christopher D|Hruban, Ralph H|Belchis, Deborah A
PMID: 26626780
Journal: Cancer Discov. 2016 Feb;6(2):166-75.
Title: Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.
Author: Roberts, Nicholas J|Norris, Alexis L|Petersen, Gloria M|Bondy, Melissa L|Brand, Randall|Gallinger, Steven|Kurtz, Robert C|Olson, Sara H|Rustgi, Anil K|Schwartz, Ann G|Stoffel, Elena|Syngal, Sapna|Zogopoulos, George|Ali, Syed Z|Axilbund, Jennifer|Chaffee,
PMID: 26658419
Journal: Cancer Cell. 2016 Jan 11;29(1):75-89.
Title: Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.
Author: Hayes, Tikvah K|Neel, Nicole F|Hu, Chaoxin|Gautam, Prson|Chenard, Melissa|Long, Brian|Aziz, Meraj|Kassner, Michelle|Bryant, Kirsten L|Pierobon, Mariaelena|Marayati, Raoud|Kher, Swapnil|George, Samuel D|Xu, Mai|Wang-Gillam, Andrea|Samatar, Ahmed A|Maitra,
PMID: 26725216
Journal: Sci Rep. 2016 Jan 12;6:19222.
Title: Mutant p53 determines pancreatic cancer poor prognosis to pancreatectomy through upregulation of cavin-1 in patients with preoperative serum CA19-9 >/= 1,000 U/mL.
Author: Xiang, Jin-Feng|Wang, Wen-Quan|Liu, Liang|Xu, Hua-Xiang|Wu, Chun-Tao|Yang, Jing-Xuan|Qi, Zi-Hao|Wang, Ya-Qi|Xu, Jin|Liu, Chen|Long, Jiang|Ni, Quan-Xing|Li, Min|Yu, Xian-Jun
PMID: 26753987
Journal: J Am Acad Dermatol. 2016 Feb;74(2):325-32.
Title: Multiple primary melanomas (MPMs) and criteria for genetic assessment: MultiMEL, a multicenter study of the Italian Melanoma Intergroup.
Author: Bruno, William|Pastorino, Lorenza|Ghiorzo, Paola|Andreotti, Virginia|Martinuzzi, Claudia|Menin, Chiara|Elefanti, Lisa|Stagni, Camilla|Vecchiato, Antonella|Rodolfo, Monica|Maurichi, Andrea|Manoukian, Siranoush|De Giorgi, Vincenzo|Savarese, Imma|Gensini, Fr
PMID: 26775776
Journal: Oncol Rep. 2016 Apr;35(4):1941-9.
Title: Emodin enhances the demethylation by 5-Aza-CdR of pancreatic cancer cell tumor-suppressor genes P16, RASSF1A and ppENK.
Author: Pan, Feng-Ping|Zhou, Hong-Kun|Bu, He-Qi|Chen, Zi-Qiang|Zhang, Hao|Xu, Lu-Ping|Tang, Jian|Yu, Qing-Jiang|Chu, Yong-Quan|Pan, Jie|Fei, Yong|Lin, Sheng-Zhang|Liu, Dian-Lei|Chen, Liang
PMID: 26782786
Journal: Cancer Biol Ther. 2016;17(3):246-53.
Title: Nanopore sequencing detects structural variants in cancer.
Author: Norris, Alexis L|Workman, Rachael E|Fan, Yunfan|Eshleman, James R|Timp, Winston
PMID: 26787508
Journal: J Med Genet. 2016 Nov;53(11):721-727.
Title: An interstitial deletion within 9p21.3 and extending beyond CDKN2A predisposes to melanoma, neural system tumours and possible haematological malignancies.
Author: Baker, Maria J|Goldstein, Alisa M|Gordon, Patricia L|Harbaugh, Kimberly S|Mackley, Heath B|Glantz, Michael J|Drabick, Joseph J
PMID: 26794401
Journal: Cell Rep. 2016 Feb 9;14(5):979-990.
Title: Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique Vulnerabilities.
Author: Franco, Jorge|Balaji, Uthra|Freinkman, Elizaveta|Witkiewicz, Agnieszka K|Knudsen, Erik S
PMID: 26804906
Journal: Lancet. 2016 Jul 2;388(10039):73-85.
Title: Pancreatic cancer.
Author: Kamisawa, Terumi|Wood, Laura D|Itoi, Takao|Takaori, Kyoichi
PMID: 26830752
Journal: Br J Dermatol. 2016 Oct;175(4):785-9.
Title: CDKN2A mutations with p14 loss predisposing to multiple nerve sheath tumours, melanoma, dysplastic naevi and internal malignancies: a case series and review of the literature.
Author: Sargen, M R|Merrill, S L|Chu, E Y|Nathanson, K L
PMID: 26876133
Journal: Sci Rep. 2016 Feb 17;6:21648.
Title: MIA PaCa-2 and PANC-1 - pancreas ductal adenocarcinoma cell lines with neuroendocrine differentiation and somatostatin receptors.
Author: Gradiz, Rui|Silva, Henriqueta C|Carvalho, Lina|Botelho, Maria Filomena|Mota-Pinto, Anabela
PMID: 26884312
Journal: J Am Acad Dermatol. 2016 Mar;74(3):395-407; quiz 408-10.
Title: Hereditary melanoma: Update on syndromes and management: Genetics of familial atypical multiple mole melanoma syndrome.
Author: Soura, Efthymia|Eliades, Philip J|Shannon, Kristen|Stratigos, Alexander J|Tsao, Hensin
PMID: 26892650
Journal: Fam Cancer. 2016 Jul;15(3):487-91.
Title: Familial atypical multiple mole melanoma (FAMMM) syndrome: history, genetics, and heterogeneity.
Author: Lynch, Henry T|Shaw, Trudy G
PMID: 26892865
Journal: Pancreatology. 2016 May-Jun;16(3):372-81.
Title: Telomerase activity in pancreatic juice differentiates pancreatic cancer from chronic pancreatitis: A meta-analysis.
Author: Hata, Tatsuo|Ishida, Masaharu|Motoi, Fuyuhiko|Yamaguchi, Takuhiro|Naitoh, Takeshi|Katayose, Yu|Egawa, Shinichi|Unno, Michiaki
PMID: 26899542
Journal: J Clin Oncol. 2016 Jun 10;34(17):2010-9.
Title: Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers.
Author: Vasen, Hans|Ibrahim, Isaura|Ponce, Carmen Guillen|Slater, Emily P|Matthai, Elvira|Carrato, Alfredo|Earl, Julie|Robbers, Kristin|van Mil, Anneke M|Potjer, Thomas|Bonsing, Bert A|de Vos Tot Nederveen Cappel, Wouter H|Bergman, Wilma|Wasser, Martin|Morreau, H
PMID: 27114589
Journal: Nat Rev Dis Primers. 2016 Apr 21;2:16022.
Title: Pancreatic cancer.
Author: Kleeff, Jorg|Korc, Murray|Apte, Minoti|La Vecchia, Carlo|Johnson, Colin D|Biankin, Andrew V|Neale, Rachel E|Tempero, Margaret|Tuveson, David A|Hruban, Ralph H|Neoptolemos, John P
PMID: 27158978
Journal: Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1185-91.
Title: Association of Common Susceptibility Variants of Pancreatic Cancer in Higher-Risk Patients: A PACGENE Study.
Author: Childs, Erica J|Chaffee, Kari G|Gallinger, Steven|Syngal, Sapna|Schwartz, Ann G|Cote, Michele L|Bondy, Melissa L|Hruban, Ralph H|Chanock, Stephen J|Hoover, Robert N|Fuchs, Charles S|Rider, David N|Amundadottir, Laufey T|Stolzenberg-Solomon, Rachael|Wolpin
PMID: 27197284
Journal: Gut. 2016 Aug;65(8):1314-21.
Title: Refinement of screening for familial pancreatic cancer.
Author: Bartsch, D K|Slater, E P|Carrato, A|Ibrahim, I S|Guillen-Ponce, C|Vasen, H F A|Matthai, E|Earl, J|Jendryschek, F S|Figiel, J|Steinkamp, M|Ramaswamy, A|Vazquez-Sequeiros, E|Munoz-Beltran, M|Montans, J|Mocci, E|Bonsing, B A|Wasser, M|Kloppel, G|Langer, P|Fe
PMID: 27222532
Journal: Cancer Lett. 2016 Aug 28;379(1):1-11.
Title: Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer.
Author: Ju, Huai-Qiang|Zhuang, Zhuo-Nan|Li, Hao|Tian, Tian|Lu, Yun-Xin|Fan, Xiao-Qiang|Zhou, Hai-Jun|Mo, Hai-Yu|Sheng, Hui|Chiao, Paul J|Xu, Rui-Hua
PMID: 27233476
Journal: Br J Surg. 2016 Aug;103(9):1189-99.
Title: Infiltrating immune cells and gene mutations in pancreatic ductal adenocarcinoma.
Author: Wang, W-Q|Liu, L|Xu, H-X|Wu, C-T|Xiang, J-F|Xu, J|Liu, C|Long, J|Ni, Q-X|Yu, X-J
PMID: 27256393
Journal: Cancer Lett. 2016 Aug 28;379(1):143-53.
Title: Combined targeting of TGF-beta, EGFR and HER2 suppresses lymphangiogenesis and metastasis in a pancreatic cancer model.
Author: Gore, Jesse|Imasuen-Williams, Imade E|Conteh, Abass M|Craven, Kelly E|Cheng, Monica|Korc, Murray
PMID: 27267807
Journal: Transl Oncol. 2016 Jun;9(3):242-7.
Title: Application of a Serum Protein Signature for Pancreatic Cancer to Separate Cases from Controls in a Pancreatic Surveillance Cohort.
Author: Potjer, Thomas P|Mertens, Bart J|Nicolardi, Simone|van der Burgt, Yuri E M|Bonsing, Bert A|Mesker, Wilma E|Tollenaar, Rob A E M|Vasen, Hans F A
PMID: 27267843
Journal: J Cell Physiol. 2016 Oct;231(10):2303.
Title: Retraction: "Inactivation of Ink4a/Arf Leads to Deregulated Expression of miRNAs in K-Ras Transgenic Mouse Model of Pancreatic Cancer" by Ali et al.
Author:
PMID: 27315161
Journal: J Cell Physiol. 2016 Oct;231(10):2304.
Title: Retraction: "Activated K-Ras and INK4a/Arf Deficiency Promote Aggressiveness of Pancreatic Cancer by Induction of EMT Consistent With Cancer Stem Cell Phenotype" by Wang et al.
Author:
PMID: 27315162
Journal: Clin Cancer Res. 2016 Dec 15;22(24):6153-6163.
Title: Screening of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3-MYC Interactions as a Target in Pancreatic Cancer.
Author: Beglyarova, Natalya|Banina, Eugenia|Zhou, Yan|Mukhamadeeva, Ramilia|Andrianov, Grigorii|Bobrov, Egor|Lysenko, Elena|Skobeleva, Natalya|Gabitova, Linara|Restifo, Diana|Pressman, Max|Serebriiskii, Ilya G|Hoffman, John P|Paz, Keren|Behrens, Diana|Khazak, Vla
PMID: 27384421
Journal: Hum Genet. 2016 Nov;135(11):1241-1249.
Title: Multiple rare variants in high-risk pancreatic cancer-related genes may increase risk for pancreatic cancer in a subset of patients with and without germline CDKN2A mutations.
Author: Yang, Xiaohong R|Rotunno, Melissa|Xiao, Yanzi|Ingvar, Christian|Helgadottir, Hildur|Pastorino, Lorenza|van Doorn, Remco|Bennett, Hunter|Graham, Cole|Sampson, Joshua N|Malasky, Michael|Vogt, Aurelie|Zhu, Bin|Bianchi-Scarra, Giovanna|Bruno, William|Queirolo
PMID: 27449771
Journal: Pathol Res Pract. 2016 Aug;212(8):726-34.
Title: P53 overexpression and Ki67-index are associated with outcome in ductal pancreatic adenocarcinoma with adjuvant gemcitabine treatment.
Author: Striefler, Jana K|Sinn, Marianne|Pelzer, Uwe|Juhling, Anja|Wislocka, Lilianna|Bahra, Marcus|Sinn, Bruno V|Denkert, Carsten|Dorken, Bernd|Oettle, Helmut|Riess, Hanno|Blaker, Hendrik|Lohneis, Philipp
PMID: 27461834
Journal: Br J Dermatol. 2016 Nov;175(5):1030-1037.
Title: Genetic susceptibility to cutaneous melanoma in southern Switzerland: role of CDKN2A, MC1R and MITF.
Author: Mangas, C|Potrony, M|Mainetti, C|Bianchi, E|Carrozza Merlani, P|Mancarella Eberhardt, A|Maspoli-Postizzi, E|Marazza, G|Marcollo-Pini, A|Pelloni, F|Sessa, C|Simona, B|Puig-Butille, J A|Badenas, C|Puig, S
PMID: 27473757
Journal: Oncotarget. 2016 Aug 30;7(35):57011-57020.
Title: Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk.
Author: Campa, Daniele|Pastore, Manuela|Gentiluomo, Manuel|Talar-Wojnarowska, Renata|Kupcinskas, Juozas|Malecka-Panas, Ewa|Neoptolemos, John P|Niesen, Willem|Vodicka, Pavel|Delle Fave, Gianfranco|Bueno-de-Mesquita, H Bas|Gazouli, Maria|Pacetti, Paola|Di Leo, Mile
PMID: 27486979
Journal: Nat Commun. 2016 Sep 2;7:12685.
Title: Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers.
Author: Muzumdar, Mandar Deepak|Dorans, Kimberly Judith|Chung, Katherine Minjee|Robbins, Rebecca|Tammela, Tuomas|Gocheva, Vasilena|Li, Carman Man-Chung|Jacks, Tyler
PMID: 27585860
Journal: Neoplasia. 2016 Oct;18(10):610-617.
Title: p53 and p16(Ink4a)/p19(Arf) Loss Promotes Different Pancreatic Tumor Types from PyMT-Expressing Progenitor Cells.
Author: Azzopardi, Stephanie|Pang, Sharon|Klimstra, David S|Du, Yi-Chieh Nancy
PMID: 27664376
Journal: Cancer Lett. 2016 Dec 1;383(1):73-84.
Title: Hypoxia induces TWIST-activated epithelial-mesenchymal transition and proliferation of pancreatic cancer cells in vitro and in nude mice.
Author: Chen, Shi|Chen, Jiang-Zhi|Zhang, Jia-Qiang|Chen, Hui-Xin|Yan, Mao-Lin|Huang, Long|Tian, Yi-Feng|Chen, Yan-Lin|Wang, Yao-Dong
PMID: 27693633
Journal: Nature. 2016 Oct 20;538(7625):378-382.
Title: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.
Author: Notta, Faiyaz|Chan-Seng-Yue, Michelle|Lemire, Mathieu|Li, Yilong|Wilson, Gavin W|Connor, Ashton A|Denroche, Robert E|Liang, Sheng-Ben|Brown, Andrew M K|Kim, Jaeseung C|Wang, Tao|Simpson, Jared T|Beck, Timothy|Borgida, Ayelet|Buchner, Nicholas|Chadwick, Di
PMID: 27732578
Journal: Adv Exp Med Biol. 2016;924:13-17.
Title: Clinical Utility of Circulating Tumor DNA for Molecular Assessment and Precision Medicine in Pancreatic Cancer.
Author: Takai, Erina|Totoki, Yasushi|Nakamura, Hiromi|Kato, Mamoru|Shibata, Tatsuhiro|Yachida, Shinichi
PMID: 27753011
Journal: Surg Clin North Am. 2016 Dec;96(6):1207-1221.
Title: Genetics of Pancreatic Cancer and Its Implications on Therapy.
Author: Tatarian, Talar|Winter, Jordan M
PMID: 27865273
Journal: Prog Mol Biol Transl Sci. 2016;144:241-275.
Title: Molecular Pathogenesis of Pancreatic Cancer.
Author: Grant, T J|Hua, K|Singh, A
PMID: 27865459
Journal: Gan To Kagaku Ryoho. 2016 Nov;43(11):1326-1331.
Title: [A Novel Treatment Strategy for Pancreatic Cancer Based on Gene Profiles].
Author: Hayashi, Hideyuki|Nishihara, Hiroshi
PMID: 27899773
Journal: Sci Rep. 2016 Dec 23;6:39565.
Title: Common germline variants within the CDKN2A/2B region affect risk of pancreatic neuroendocrine tumors.
Author: Campa, Daniele|Capurso, Gabriele|Pastore, Manuela|Talar-Wojnarowska, Renata|Milanetto, Anna Caterina|Landoni, Luca|Maiello, Evaristo|Lawlor, Rita T|Malecka-Panas, Ewa|Funel, Niccola|Gazouli, Maria|De Bonis, Antonio|Kluter, Harald|Rinzivillo, Maria|Delle F
PMID: 28008994
Journal: Fam Cancer. 2017 Jan;16(1):111-115.
Title: Dilemmas in the management of screen-detected lesions in patients at high risk for pancreatic cancer.
Author: Ibrahim, Isaura S|Bonsing, Bert A|Swijnenburg, Rutger-Jan|Welling, Lieke|Veenendaal, Roeland A|Wasser, Martin N J M|Morreau, Hans|Inderson, Akin|Vasen, Hans F A
PMID: 27406244
Journal: J Clin Pathol. 2017 Feb;70(2):174-178.
Title: Targeted next-generation sequencing of FNA-derived DNA in pancreatic cancer.
Author: Sibinga Mulder, Babs G|Mieog, J Sven D|Handgraaf, Henricus J M|Farina Sarasqueta, Arantza|Vasen, Hans F A|Potjer, Thomas P|Swijnenburg, Rutger-Jan|Luelmo, Saskia A C|Feshtali, Shirin|Inderson, Akin|Vahrmeijer, Alexander L|Bonsing, Bert A|van Wezel, Tom|Mo
PMID: 27672215
Journal: Mol Cancer Res. 2017 Jan;15(1):3-14.
Title: Senescent Carcinoma-Associated Fibroblasts Upregulate IL8 to Enhance Prometastatic Phenotypes.
Author: Wang, Tao|Notta, Faiyaz|Navab, Roya|Joseph, Joella|Ibrahimov, Emin|Xu, Jing|Zhu, Chang-Qi|Borgida, Ayelet|Gallinger, Steven|Tsao, Ming-Sound
PMID: 27678171
Journal: Fam Cancer. 2017 Apr;16(2):257-265.
Title: Uptake of genetic counseling, genetic testing and surveillance in hereditary malignant melanoma (CDKN2A) in Norway.
Author: Levin, Trine|Maehle, Lovise
PMID: 27804060
Journal: Am J Surg Pathol. 2017 Mar;41(3):313-325.
Title: Intraductal Tubulopapillary Neoplasm of the Pancreas: A Clinicopathologic and Immunohistochemical Analysis of 33 Cases.
Author: Basturk, Olca|Adsay, Volkan|Askan, Gokce|Dhall, Deepti|Zamboni, Giuseppe|Shimizu, Michio|Cymes, Karina|Carneiro, Fatima|Balci, Serdar|Sigel, Carlie|Reid, Michelle D|Esposito, Irene|Baldaia, Helena|Allen, Peter|Kloppel, Gunter|Klimstra, David S
PMID: 27984235
Journal: Clin Cancer Res. 2017 Jun 15;23(12):3129-3138.
Title: Immune Cytolytic Activity Stratifies Molecular Subsets of Human Pancreatic Cancer.
Author: Balli, David|Rech, Andrew J|Stanger, Ben Z|Vonderheide, Robert H
PMID: 28007776
Journal: Pancreas. 2017 Mar;46(3):335-340.
Title: Utility of Assessing the Number of Mutated KRAS, CDKN2A, TP53, and SMAD4 Genes Using a Targeted Deep Sequencing Assay as a Prognostic Biomarker for Pancreatic Cancer.
Author: Hayashi, Hideyuki|Kohno, Takashi|Ueno, Hideki|Hiraoka, Nobuyoshi|Kondo, Shunsuke|Saito, Motonobu|Shimada, Yoko|Ichikawa, Hitoshi|Kato, Mamoru|Shibata, Tatsuhiro|Morizane, Chigusa|Sakamoto, Yasunari|Shimada, Kazuaki|Komatsu, Yoshito|Sakamoto, Naoya|Okusaka
PMID: 28099251
Journal: G Ital Dermatol Venereol. 2017 Jun;152(3):262-265.
Title: Familial melanoma and multiple primary melanoma.
Author: DE Simone, Paola|Valiante, Michele|Silipo, Vitaliano
PMID: 28121081
Journal: Mol Cancer Ther. 2017 Apr;16(4):662-670.
Title: Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma.
Author: Dai, Bingbing|Roife, David|Kang, Ya'an|Gumin, Joy|Rios Perez, Mayrim V|Li, Xinqun|Pratt, Michael|Brekken, Rolf A|Fueyo-Margareto, Juan|Lang, Frederick F|Fleming, Jason B
PMID: 28138026
Journal: Dig Endosc. 2017 Sep;29(6):657-666.
Title: Team work and cytopathology molecular diagnosis of solid pancreatic lesions.
Author: Fabbri, Carlo|Gibiino, Giulia|Fornelli, Adele|Cennamo, Vincenzo|Grifoni, Daniela|Visani, Michela|Acquaviva, Giorgia|Fassan, Matteo|Fiorino, Sirio|Giovanelli, Silvia|Bassi, Marco|Ghersi, Stefania|Tallini, Giovanni|Jovine, Elio|Gasbarrini, Antonio|de Biase,
PMID: 28190274
Journal: Pancreas. 2017 May/Jun;46(5):614-618.
Title: Methylation of Tumor Suppressor Genes in Autoimmune Pancreatitis.
Author: Kinugawa, Yasuhiro|Uehara, Takeshi|Sano, Kenji|Matsuda, Kazuyuki|Maruyama, Yasuhiro|Kobayashi, Yukihiro|Nakajima, Tomoyuki|Hamano, Hideaki|Kawa, Shigeyuki|Higuchi, Kayoko|Hosaka, Noriko|Shiozawa, Satoshi|Ishigame, Hiroki|Ota, Hiroyoshi
PMID: 28196014
Journal: Nat Commun. 2017 Mar 8;8:14686.
Title: Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells.
Author: Lee, Jonghyeob|Snyder, Emily R|Liu, Yinghua|Gu, Xueying|Wang, Jing|Flowers, Brittany M|Kim, Yoo Jung|Park, Sangbin|Szot, Gregory L|Hruban, Ralph H|Longacre, Teri A|Kim, Seung K
PMID: 28272465
Journal: Cancer Metastasis Rev. 2017 Mar;36(1):77-90.
Title: Identification, genetic testing, and management of hereditary melanoma.
Author: Leachman, Sancy A|Lucero, Olivia M|Sampson, Jone E|Cassidy, Pamela|Bruno, William|Queirolo, Paola|Ghiorzo, Paola
PMID: 28283772
Journal: Int J Biol Macromol. 2017 Sep;102:718-728.
Title: The over expression of long non-coding RNA ANRIL promotes epithelial-mesenchymal transition by activating the ATM-E2F1 signaling pathway in pancreatic cancer: An in vivo and in vitro study.
Author: Chen, Shi|Zhang, Jia-Qiang|Chen, Jiang-Zhi|Chen, Hui-Xing|Qiu, Fu-Nan|Yan, Mao-Lin|Chen, Yan-Ling|Peng, Cheng-Hong|Tian, Yi-Feng|Wang, Yao-Dong
PMID: 28344092
Journal: Clin Cancer Res. 2017 Apr 1;23(7):1629-1637.
Title: Pancreatic Cancer: "A Riddle Wrapped in a Mystery inside an Enigma".
Author: Borazanci, Erkut|Dang, Chi V|Robey, Robert W|Bates, Susan E|Chabot, John A|Von Hoff, Daniel D
PMID: 28373361
Journal: Cancers (Basel). 2017 Apr 28;9(5). pii: cancers9050042.
Title: KRAS, TP53, CDKN2A, SMAD4, BRCA1, and BRCA2 Mutations in Pancreatic Cancer.
Author: Cicenas, Jonas|Kvederaviciute, Kotryna|Meskinyte, Ingrida|Meskinyte-Kausiliene, Edita|Skeberdyte, Aiste|Cicenas, Jonas
PMID: 28452926
Journal: Cancer Treat Rev. 2017 May;56:28-35.
Title: Unraveling molecular pathways of poorly differentiated neuroendocrine carcinomas of the gastroenteropancreatic system: A systematic review.
Author: Girardi, Daniel M|Silva, Andrea C B|Rego, Juliana Florinda M|Coudry, Renata A|Riechelmann, Rachel P
PMID: 28456055
Journal: PLoS One. 2017 May 5;12(5):e0176844.
Title: LSL-KrasG12D; LSL-Trp53R172H/+; Ink4flox/+; Ptf1/p48-Cre mice are an applicable model for locally invasive and metastatic pancreatic cancer.
Author: Ma, Lixiang|Saiyin, Hexige
PMID: 28475592
Journal: Cancer Lett. 2017 Aug 28;402:110-116.
Title: Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
Author: Nagaraju, Ganji Purnachandra|Wu, Christina|Merchant, Neha|Chen, Zhengjia|Lesinski, Gregory B|El-Rayes, Bassel F
PMID: 28583846
Journal: J Med Genet. 2017 Sep;54(9):607-612.
Title: Germline CDKN2A/P16INK4A mutations contribute to genetic determinism of sarcoma.
Author: Jouenne, Fanelie|Chauvot de Beauchene, Isaure|Bollaert, Emeline|Avril, Marie-Francoise|Caron, Olivier|Ingster, Olivier|Lecesne, Axel|Benusiglio, Patrick|Terrier, Philippe|Caumette, Vincent|Pissaloux, Daniel|de la Fouchardiere, Arnaud|Cabaret, Odile|N'Diay
PMID: 28592523
Journal: Br J Cancer. 2017 Aug 8;117(4):572-582.
Title: Clinical study of genomic drivers in pancreatic ductal adenocarcinoma.
Author: Barrett, Michael T|Deiotte, Ray|Lenkiewicz, Elizabeth|Malasi, Smriti|Holley, Tara|Evers, Lisa|Posner, Richard G|Jones, Timothy|Han, Haiyong|Sausen, Mark|Velculescu, Victor E|Drebin, Jeffrey|O'Dwyer, Peter|Jameson, Gayle|Ramanathan, Ramesh K|Von Hoff, Dani
PMID: 28720843
Journal: J Clin Oncol. 2017 Oct 20;35(30):3382-3390.
Title: Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma.
Author: Shindo, Koji|Yu, Jun|Suenaga, Masaya|Fesharakizadeh, Shahriar|Cho, Christy|Macgregor-Das, Anne|Siddiqui, Abdulrehman|Witmer, P Dane|Tamura, Koji|Song, Tae Jun|Navarro Almario, Jose Alejandro|Brant, Aaron|Borges, Michael|Ford, Madeline|Barkley, Thomas|He,
PMID: 28767289
Journal: J Assoc Genet Technol. 2017;43(3):113-127.
Title: Elucidation of Novel Chromosomal Abnormalities in Pancreatic Cancer: Conventional and Molecular Cytogenetic Characterization of 16 Pancreatic Cell Lines.
Author: Shabsovich, David|Tirado, Carlos A
PMID: 28809762
Journal: Sci Rep. 2017 Sep 11;7(1):11144.
Title: ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer.
Author: Drosos, Yiannis|Escobar, David|Chiang, Ming-Yi|Roys, Kathryn|Valentine, Virginia|Valentine, Marc B|Rehg, Jerold E|Sahai, Vaibhav|Begley, Lesa A|Ye, Jianming|Paul, Leena|McKinnon, Peter J|Sosa-Pineda, Beatriz
PMID: 28894253
Journal: Biochem Biophys Res Commun. 2017 Nov 18;493(2):1018-1025.
Title: ARID1A suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/CDKN2A regulatory axis.
Author: Li, Zhao-Yun|Zhu, Shan-Shan|Chen, Xian-Jun|Zhu, Jie|Chen, Qi|Zhang, Ya-Qiong|Zhang, Chun-Ling|Guo, Ting-Ting|Zhang, Li-Ming
PMID: 28942143
Journal: World J Gastrointest Oncol. 2017 Sep 15;9(9):390-396.
Title: Pancreatic adenosquamous carcinoma and intraductal papillary mucinous neoplasm in a CDKN2A germline mutation carrier.
Author: Martinez de Juan, Fernando|Reolid Escribano, Maria|Martinez Lapiedra, Carmen|Maia de Alcantara, Fernanda|Caballero Soto, Maria|Calatrava Fons, Ana|Machado, Isidro
PMID: 28979722
Journal: Oncotarget. 2017 Apr 20;8(42):73240-73257.
Title: Germline mutations in pancreatic cancer and potential new therapeutic options.
Author: Pihlak, Rille|Valle, Juan W|McNamara, Mairead G
PMID: 29069866
Journal: Gut. 2017 Oct 28. pii: gutjnl-2017-315144.
Title: Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer.
Author: Chou, Angela|Froio, Danielle|Nagrial, Adnan M|Parkin, Ashleigh|Murphy, Kendelle J|Chin, Venessa T|Wohl, Dalia|Steinmann, Angela|Stark, Rhys|Drury, Alison|Walters, Stacey N|Vennin, Claire|Burgess, Andrew|Pinese, Mark|Chantrill, Lorraine A|Cowley, Mark J|Mo
PMID: 29080858
Journal: Biomedicines. 2017 Nov 18;5(4). pii: biomedicines5040065.
Title: Pancreatic Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells.
Author: Pelosi, Elvira|Castelli, Germana|Testa, Ugo
PMID: 29156578
Journal: PLoS One. 2017 Dec 7;12(12):e0189123.
Title: Functional analysis of a CDKN2A 5'UTR germline variant associated with pancreatic cancer development.
Author: Bruno, William|Andreotti, Virginia|Bisio, Alessandra|Pastorino, Lorenza|Fornarini, Giuseppe|Sciallero, Stefania|Bianchi-Scarra, Giovanna|Inga, Alberto|Ghiorzo, Paola
PMID: 29216274
Journal: J Biol Regul Homeost Agents. 2017 Oct-Dec;31(4):1043-1047.
Title: p16 gene expression in pancreatic cancer tissue and its importance in diagnosis.
Author: Mou, H|Yu, L|Zheng, X|Liao, Q|Hou, X|Wu, Y
PMID: 29254312
Journal: Sci Rep. 2017 Dec 22;7(1):18056.
Title: Worsened outcome in patients with pancreatic ductal carcinoma on long-term diabetes: association with E-cadherin1 (CDH1) promoter methylation.
Author: Saito, Takeshi|Mizukami, Hiroki|Umetsu, Satoko|Uchida, Chiaki|Inaba, Wataru|Abe, Makoto|Takahashi, Kazuhisa|Kudo, Kazuhiro|Itabashi, Chieko|Yagihashi, Soroku|Hakamada, Kenichi
PMID: 29273724
Journal: Genet Med. 2018 Jan;20(1):119-127.
Title: Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history.
Author: Chaffee, Kari G|Oberg, Ann L|McWilliams, Robert R|Majithia, Neil|Allen, Brian A|Kidd, John|Singh, Nanda|Hartman, Anne-Renee|Wenstrup, Richard J|Petersen, Gloria M
PMID: 28726808
Journal: Oncogene. 2018 Jan 4;37(1):128-138.
Title: CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A.
Author: Tu, Q|Hao, J|Zhou, X|Yan, L|Dai, H|Sun, B|Yang, D|An, S|Lv, L|Jiao, B|Chen, C|Lai, R|Shi, P|Zhao, X
PMID: 28892048
Journal: Fam Cancer. 2018 Jan;17(1):101-111.
Title: Development of a high risk pancreatic screening clinic using 3.0 T MRI.
Author: Barnes, Chad A|Krzywda, Elizabeth|Lahiff, Shannon|McDowell, Dena|Christians, Kathleen K|Knechtges, Paul|Tolat, Parag|Hohenwalter, Mark|Dua, Kulwinder|Khan, Abdul H|Evans, Douglas B|Geurts, Jennifer|Tsai, Susan
PMID: 29101607
Journal: Cancer Biomark. 2018 Feb 6;21(2):323-334.
Title: Long-term survivors of pancreatic adenocarcinoma show low rates of genetic alterations in KRAS, TP53 and SMAD4.
Author: Masetti, Michele|Acquaviva, Giorgia|Visani, Michela|Tallini, Giovanni|Fornelli, Adele|Ragazzi, Moira|Vasuri, Francesco|Grifoni, Daniela|Di Giacomo, Simone|Fiorino, Sirio|Lombardi, Raffaele|Tuminati, David|Ravaioli, Matteo|Fabbri, Carlo|Bacchi-Reggiani, Ma
PMID: 29103024
Journal: Oncol Rep. 2018 Jan;39(1):264-270.
Title: Synergistic effects of the combination of 5-AzaCdR and suberoylanilide hydroxamic acid on the anticancer property of pancreatic cancer.
Author: Han, Ting|Zhuo, Meng|Hu, Hai|Jiao, Feng|Wang, Li-Wei
PMID: 29115632
Journal: Mol Med Rep. 2018 Feb;17(2):2614-2618.
Title: Overexpression of p16ink4a regulates the Wnt/betacatenin signaling pathway in pancreatic cancer cells.
Author: Zhang, Hui|Li, Xun|Meng, Wenbo|Zhang, Lei|Zhu, Xiaoliang|Bai, Zhongtian|Yan, Jun|Zhou, Wence
PMID: 29207089
Journal: J Cancer. 2018 Jan 1;9(1):21-31.
Title: Integrated Analysis of Long Non-Coding RNA and mRNA Expression Profile in Pancreatic Cancer Derived Exosomes Treated Dendritic Cells by Microarray Analysis.
Author: Chen, Jionghuang|Wang, Shaowen|Jia, Shengnan|Ding, Guoping|Jiang, Guixing|Cao, Liping
PMID: 29290766
Journal: Cell Stem Cell. 2018 Mar 1;22(3):454-467.e6.
Title: Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression.
Author: Seino, Takashi|Kawasaki, Shintaro|Shimokawa, Mariko|Tamagawa, Hiroki|Toshimitsu, Kohta|Fujii, Masayuki|Ohta, Yuki|Matano, Mami|Nanki, Kosaku|Kawasaki, Kenta|Takahashi, Sirirat|Sugimoto, Shinya|Iwasaki, Eisuke|Takagi, Junichi|Itoi, Takao|Kitago, Minoru|Kit
PMID: 29337182
Journal: Nature. 2018 Feb 1;554(7690):62-68.
Title: Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
Author: Mueller, Sebastian|Engleitner, Thomas|Maresch, Roman|Zukowska, Magdalena|Lange, Sebastian|Kaltenbacher, Thorsten|Konukiewitz, Bjorn|Ollinger, Rupert|Zwiebel, Maximilian|Strong, Alex|Yen, Hsi-Yu|Banerjee, Ruby|Louzada, Sandra|Fu, Beiyuan|Seidler, Barbara|G
PMID: 29364867
Journal: Ir J Med Sci. 2018 Aug;187(3):629-637.
Title: p16, p21, and p53 proteins play an important role in development of pancreatic intraepithelial neoplastic.
Author: Zinczuk, Justyna|Zareba, Konrad|Guzinska-Ustymowicz, Katarzyna|Kedra, Boguslaw|Kemona, Andrzej|Pryczynicz, Anna
PMID: 29388054
Journal: J Invest Dermatol. 2018 Jul;138(7):1620-1626.
Title: Risks of Melanoma and Other Cancers in Melanoma-Prone Families over 4 Decades.
Author: Tucker, Margaret A|Elder, David E|Curry, Michael|Fraser, Mary C|Pichler, Virginia|Zametkin, Deborah|Yang, Xiaohong R|Goldstein, Alisa M
PMID: 29408205
Journal: Melanoma Res. 2018 Jun;28(3):246-249.
Title: CDKN2A germline alterations in melanoma patients with personal or familial history of pancreatic cancer.
Author: De Unamuno, Blanca|Garcia-Casado, Zaida|Banuls, Jose|Requena, Celia|Lopez-Guerrero, Jose Antonio|Nagore, Eduardo
PMID: 29543703
Journal: Hum Pathol. 2018 Jul;77:70-79.
Title: Pancreatic neuroendocrine carcinomas reveal a closer relationship to ductal adenocarcinomas than to neuroendocrine tumors G3.
Author: Konukiewitz, Bjorn|Jesinghaus, Moritz|Steiger, Katja|Schlitter, Anna Melissa|Kasajima, Atsuko|Sipos, Bence|Zamboni, Giuseppe|Weichert, Wilko|Pfarr, Nicole|Kloppel, Gunter
PMID: 29596894
Journal: Clin Cancer Res. 2018 Sep 15;24(18):4444-4454.
Title: Integrated Genomic and Immunophenotypic Classification of Pancreatic Cancer Reveals Three Distinct Subtypes with Prognostic/Predictive Significance.
Author: Wartenberg, Martin|Cibin, Silvia|Zlobec, Inti|Vassella, Erik|Eppenberger-Castori, Serenella|Terracciano, Luigi|Eichmann, Micha David|Worni, Mathias|Gloor, Beat|Perren, Aurel|Karamitopoulou, Eva
PMID: 29661773
Journal: J Med Genet. 2018 Oct;55(10):661-668.
Title: CM-Score: a validated scoring system to predict CDKN2A germline mutations in melanoma families from Northern Europe.
Author: Potjer, Thomas P|Helgadottir, Hildur|Leenheer, Mirjam|van der Stoep, Nienke|Gruis, Nelleke A|Hoiom, Veronica|Olsson, Hakan|van Doorn, Remco|Vasen, Hans F A|van Asperen, Christi J|Dekkers, Olaf M|Hes, Frederik J
PMID: 29661971
Journal: Eur J Hum Genet. 2018 May 16. pii: 10.1038/s41431-018-0170-y.
Title: Risk of multiple pancreatic cancers in CDKN2A-p16-Leiden mutation carriers.
Author: Ibrahim, Isaura|Sibinga Mulder, Babs G|Bonsing, Bert|Morreau, Hans|Farina Sarasqueta, Arantza|Inderson, Akin|Luelmo, Saskia|Feshtali, Shirin|Potjer, Thomas P|de Vos Tot Nederveen Cappel, Wouter|Wasser, Martin|Vasen, Hans F A
PMID: 29769629
Journal: Virchows Arch. 2018 Sep;473(3):305-311.
Title: Gastric gland mucin-specific O-glycan expression decreases as tumor cells progress from lobular endocervical gland hyperplasia to cervical mucinous carcinoma, gastric type.
Author: Yamanoi, Kazuhiro|Ishii, Keiko|Tsukamoto, Michihiko|Asaka, Shiho|Nakayama, Jun
PMID: 29845361
Journal: JAMA. 2018 Jun 19;319(23):2401-2409.
Title: Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
Author: Hu, Chunling|Hart, Steven N|Polley, Eric C|Gnanaolivu, Rohan|Shimelis, Hermela|Lee, Kun Y|Lilyquist, Jenna|Na, Jie|Moore, Raymond|Antwi, Samuel O|Bamlet, William R|Chaffee, Kari G|DiCarlo, John|Wu, Zhong|Samara, Raed|Kasi, Pashtoon M|McWilliams, Robert R|
PMID: 29922827
Journal: An Bras Dermatol. 2018 Jun;93(3):337-340.
Title: Hereditary melanoma: a five-year study of Brazilian patients in a cancer referral center - phenotypic characteristics of probands and pathological features of primary tumors.
Author: Sa, Bianca Costa Soares de|Moredo, Luciana Facure|Gomes, Elimar Elias|Araujo, Erica Sara Souza de|Duprat, Joao Pedreira
PMID: 29924249
Journal: Genet Med. 2018 Jul 2. pii: 10.1038/s41436-018-0009-5.
Title: Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer.
Author: Yurgelun, Matthew B|Chittenden, Anu B|Morales-Oyarvide, Vicente|Rubinson, Douglas A|Dunne, Richard F|Kozak, Margaret M|Qian, Zhi Rong|Welch, Marisa W|Brais, Lauren K|Da Silva, Annacarolina|Bui, Justin L|Yuan, Chen|Li, Tingting|Li, Wanwan|Masuda, Atsuhiro|
PMID: 29961768
Journal: Cancer Epidemiol Biomarkers Prev. 2018 Jul 23. pii: 1055-9965.EPI-17-1065.
Title: CDKN2A Germline Rare Coding Variants and Risk of Pancreatic Cancer in Minority Populations.
Author: McWilliams, Robert R|Wieben, Eric D|Chaffee, Kari G|Antwi, Samuel O|Raskin, Leon|Olopade, Olufunmilayo I|Li, Donghui|Highsmith, W Edward|Colon-Otero, Gerardo|Khanna, Lauren G|Permuth, Jennifer B|Olson, Janet E|Frucht, Harold|Genkinger, Jeanine M|Zheng, We
PMID: 30038052
Journal: Pancreas. 2018 Sep;47(8):924-936.
Title: Germline Variants and Risk for Pancreatic Cancer: A Systematic Review and Emerging Concepts.
Author: Zhan, Wei|Shelton, Celeste A|Greer, Phil J|Brand, Randall E|Whitcomb, David C
PMID: 30113427
Journal: Gastrointest Endosc. 2018 Aug 23. pii: S0016-5107(18)32987-0.
Title: Chronic pancreatitis changes in high-risk individuals for pancreatic ductal adenocarcinoma.
Author: Thiruvengadam, Sushrut S|Chuang, Judith|Huang, Robert|Girotra, Mohit|Park, Walter G
PMID: 30145314
Journal: Oncol Rep. 2018 Nov;40(5):2916-2925.
Title: The interaction between miR148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer.
Author: Hong, Le|Sun, Gen|Peng, Long|Tu, Yi|Wan, Zhen|Xiong, Haiwei|Li, Yong|Xiao, Weidong
PMID: 30226601
Journal: Pathobiology. 2018 Sep 18:1-6.
Title: Early Loss of Forkhead Transcription Factor, O Subgroup, Member 1 Protein in the Development of Pancreatic Ductal Adenocarcinoma.
Author: Al-Zoughbi, Wael|Schauer, Silvia|Pichler, Martin|Hoefler, Gerald
PMID: 30227407
Journal: Mol Cancer Ther. 2018 Sep 25. pii: 1535-7163.MCT-18-0082.
Title: Cyclooxygenase-2 Influences Response to Co-Targeting of MEK and CDK4/6 in a Subpopulation of Pancreatic Cancers.
Author: Maust, Joel D|Frankowski-McGregor, Christy L|Bankhead, Armand|Simeone, Diane M|Sebolt-Leopold, Judith S
PMID: 30254182
Journal: PLoS One. 2018 Oct 2;13(10):e0205289.
Title: Retraction: Activated K-ras and INK4a/Arf Deficiency Cooperate During the Development of Pancreatic Cancer by Activation of Notch and NF-kappaB Signaling Pathways.
Author:
PMID: 30278076
Journal: Mol Cancer Ther. 2018 Oct 9. pii: 1535-7163.MCT-17-1298.
Title: Monitoring tumor burden in response to FOLFIRINOX chemotherapy via profiling circulating cell-free DNA in pancreatic cancer.
Author: Wei, Tao|Zhang, Qi|Li, Xiang|Su, Wei|Li, Guogang|Ma, Tao|Gao, Shunliang|Lou, Jianying|Que, Risheng|Zheng, Lei|Bai, Xueli|Liang, Tingbo
PMID: 30301865