HIV Target gene Detail Information

> ZZEF1 Gene Search Result

Gene Information

Gene Name	ZZEF1
Gene ID	23140
Gene Full Name	zinc finger ZZ-type and EF-hand domain containing 1
Gene Alias	ZZZ4
Transcripts	ENSG00000074755
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	O43149
HGNC ID	HGNC:29027
VEGA ID	OTTHUMG00000090741
String ID	9606.ENSP00000371051
PharmGKB ID	PA134938508

Target gene [ZZEF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003181	chr17	33	16	18	67	View
4004991	chr17	34	3		37	View
4006077	chr17	17	1	9	27	View
4006188	chr17	26			26	View
4006367	chr17	17	1	7	25	View
4012911	chr17	2	2		4	View
4013442	chr17	1	2		3	View
4013522	chr17	1	2		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZZEF1 expression and immune infiltrating cell level correlation result in HIV+ samples
ZZEF1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZZEF1 expression and immune infiltrating cell level correlation result in HIV+ samples
ZZEF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).