HBV Target gene Detail Information

> ZYG11B Gene Search Result


Gene Information
Gene Name ZYG11B
Gene ID 79699
Gene Full Name zyg-11 family member B, cell cycle regulator
Gene Alias ZYG11
Transcripts ENSG00000162378
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;Intermediate filaments;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9C0D3
HGNC ID HGNC:25820
VEGA ID OTTHUMG00000008938
OMIM ID 618673
String ID 9606.ENSP00000294353
PharmGKB ID PA142670468
Target gene [ZYG11B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007285 chr1 26 1 1 28 View
1011688 chr1 4 4 8 View
1017361 chr1 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZYG11B expression and immune infiltrating cell level correlation result in HBV+ samples
ZYG11B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).