HTLV1 Target gene Detail Information

> ZXDA Gene Search Result


Gene Information
Gene Name ZXDA
Gene ID 7789
Gene Full Name zinc finger X-linked duplicated A
Gene Alias ZNF896
Transcripts ENSG00000198205
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID P98168
HGNC ID HGNC:13198
VEGA ID OTTHUMG00000021688
OMIM ID 300235
String ID 9606.ENSP00000351530
PharmGKB ID PA37763
Target gene [ZXDA] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000249 chrX 1783 443 418 2644 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ZXDA expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZXDA expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ZXDA expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZXDA expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ZXDA expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZXDA expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).