HIV Target gene Detail Information

> ZRSR2 Gene Search Result

Gene Information

Gene Name	ZRSR2
Gene ID	8233
Gene Full Name	zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
Gene Alias	URP; ZC3H22; U2AF1L2; U2AF1RS2; U2AF1-RS2
Transcripts	ENSG00000169249
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins
Uniport_ID	Q15696
HGNC ID	HGNC:23019
VEGA ID	OTTHUMG00000021184
OMIM ID	300028
String ID	9606.ENSP00000303015
PharmGKB ID	PA162410930

Target gene [ZRSR2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013063	chrX	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZRSR2 expression and immune infiltrating cell level correlation result in HIV+ samples
ZRSR2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZRSR2 expression and immune infiltrating cell level correlation result in HIV+ samples
ZRSR2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).