HBV Target gene Detail Information

> ZNRF2 Gene Search Result


Gene Information
Gene Name ZNRF2
Gene ID 223082
Gene Full Name zinc and ring finger 2
Gene Alias RNF202
Transcripts ENSG00000180233
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;Nucleoli fibrillar center;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q8NHG8
HGNC ID HGNC:22316
VEGA ID OTTHUMG00000097759
OMIM ID 612061
String ID 9606.ENSP00000323879
PharmGKB ID PA134961488
Target gene [ZNRF2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009538 chr7 13 1 1 15 View
1009539 chr7 14 1 15 View
1400544 chr7 29 29 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZNRF2 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNRF2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).