HTLV1 Target gene Detail Information

> ZNF786 Gene Search Result


Gene Information
Gene Name ZNF786
Gene ID 136051
Gene Full Name zinc finger protein 786
Transcripts ENSG00000197362
Virus HTLV1
Gene Type protein coding
HPA Location Info Nuclear speckles;Nuclear bodies;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q8N393
HGNC ID HGNC:21806
VEGA ID OTTHUMG00000158975
String ID 9606.ENSP00000417470
PharmGKB ID PA162410468
Target gene [ZNF786] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6014306 chr7 16 1 17 View
6017772 chr7 10 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ZNF786 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF786 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ZNF786 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF786 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).