HPV Target gene Detail Information

> ZNF781 Gene Search Result

Gene Information

Gene Name	ZNF781
Gene ID	163115
Gene Full Name	zinc finger protein 781
Transcripts	ENSG00000196381
Virus	HPV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q8N8C0
HGNC ID	HGNC:26745
VEGA ID	OTTHUMG00000182106
String ID	9606.ENSP00000351391
PharmGKB ID	PA162410427

Target gene [ZNF781] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5401966	chr19	4	1		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of ZNF781 expression and immune infiltrating cell level correlation result in HPV+ samples
ZNF781 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of ZNF781 expression and immune infiltrating cell level correlation result in HPV+ samples
ZNF781 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).