HTLV1 Target gene Detail Information

> ZNF75A Gene Search Result

Gene Information

Gene Name	ZNF75A
Gene ID	7627
Gene Full Name	zinc finger protein 75a
Transcripts	ENSG00000162086
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli fibrillar center;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q96N20
HGNC ID	HGNC:13146
VEGA ID	OTTHUMG00000129356
OMIM ID	601473
String ID	9606.ENSP00000459566
PharmGKB ID	PA37720

Target gene [ZNF75A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000261	chr16	2369	137	17	2523	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ZNF75A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF75A expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ZNF75A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF75A expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ZNF75A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF75A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).