HTLV1 Target gene Detail Information

> ZNF747 Gene Search Result

Gene Information

Gene Name	ZNF747
Gene ID	65988
Gene Full Name	zinc finger protein 747
Transcripts	ENSG00000169955
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Centrosome;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9BV97
HGNC ID	HGNC:28350
VEGA ID	OTTHUMG00000132401
String ID	9606.ENSP00000252799
PharmGKB ID	PA144596521

Target gene [ZNF747] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6006059	chr16	66	8	1	75	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ZNF747 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF747 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ZNF747 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF747 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).