HIV Target gene Detail Information

> ZNF746 Gene Search Result

Gene Information

Gene Name	ZNF746
Gene ID	155061
Gene Full Name	zinc finger protein 746
Gene Alias	PARIS
Transcripts	ENSG00000181220
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q6NUN9
HGNC ID	HGNC:21948
VEGA ID	OTTHUMG00000158972
OMIM ID	613914
String ID	9606.ENSP00000395007
PharmGKB ID	PA144596520

Target gene [ZNF746] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007473	chr7	19			19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZNF746 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF746 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZNF746 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF746 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).