HBV Target gene Detail Information

> ZNF727 Gene Search Result


Gene Information
Gene Name ZNF727
Gene ID 442319
Gene Full Name zinc finger protein 727
Gene Alias ZNF727P
Transcripts ENSG00000214652
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID A8MUV8
HGNC ID HGNC:22785
VEGA ID OTTHUMG00000156536
PharmGKB ID PA162410231
Target gene [ZNF727] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008295 chr7 21 21 View
1017521 chr7 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZNF727 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF727 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).