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HBV Target gene Detail Information

> ZNF704 Gene Search Result


Gene Information
Gene Name ZNF704
Gene ID 619279
Gene Full Name zinc finger protein 704
Gene Alias Gig1
Transcripts ENSG00000164684
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q6ZNC4
HGNC ID HGNC:32291
VEGA ID OTTHUMG00000164733
String ID 9606.ENSP00000331462
PharmGKB ID PA142670501
Target gene [ZNF704] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006909 chr8 32 32 View
1009762 chr8 12 1 1 14 View
1015876 chr8 1 1 2 View
1401328 chr8 32 32 View
1401329 chr8 12 1 1 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ZNF704 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ZNF704 expression: Low -> High
Lollipop of ZNF704 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ZNF704 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZNF704 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF704 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).