HBV Target gene Detail Information

> ZNF680 Gene Search Result

Gene Information

Gene Name	ZNF680
Gene ID	340252
Gene Full Name	zinc finger protein 680
Transcripts	ENSG00000173041
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q8NEM1
HGNC ID	HGNC:26897
VEGA ID	OTTHUMG00000156542
String ID	9606.ENSP00000309330
PharmGKB ID	PA142670481

Target gene [ZNF680] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007724	chr7	19	6		25	View
1012528	chr7	5	1		6	View
1013722	chr7	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ZNF680 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF680 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).