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HTLV1 Target gene Detail Information

> ZNF672 Gene Search Result


Gene Information
Gene Name ZNF672
Gene ID 79894
Gene Full Name zinc finger protein 672
Transcripts ENSG00000171161
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q499Z4
HGNC ID HGNC:26179
VEGA ID OTTHUMG00000040377
String ID 9606.ENSP00000421915
PharmGKB ID PA142670473
Target gene [ZNF672] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000159 chr1 3139 242 214 3595 View
6011353 chr1 21 1 5 27 View
6011624 chr1 19 2 5 26 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ZNF672 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF672 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ZNF672 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF672 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ZNF672 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF672 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).