HIV Target gene Detail Information

> ZNF654 Gene Search Result

Gene Information

Gene Name	ZNF654
Gene ID	55279
Gene Full Name	zinc finger protein 654
Transcripts	ENSG00000175105
Virus	HIV
Gene Type	protein coding
HPA Location Info	Microtubules;Cytokinetic bridge;Mitotic spindle;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q8IZM8
HGNC ID	HGNC:25612
VEGA ID	OTTHUMG00000159097
String ID	9606.ENSP00000312141
PharmGKB ID	PA134923001

Target gene [ZNF654] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000297	chr3	447	58	65	570	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZNF654 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF654 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZNF654 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF654 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).