HIV Target gene Detail Information

> ZNF621 Gene Search Result

Gene Information

Gene Name	ZNF621
Gene ID	285268
Gene Full Name	zinc finger protein 621
Transcripts	ENSG00000172888
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q6ZSS3
HGNC ID	HGNC:24787
VEGA ID	OTTHUMG00000131389
String ID	9606.ENSP00000340841
PharmGKB ID	PA134982950

Target gene [ZNF621] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004165	chr3	48			48	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZNF621 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF621 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZNF621 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF621 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).