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HPV Target gene Detail Information

> ZNF611 Gene Search Result


Gene Information
Gene Name ZNF611
Gene ID 81856
Gene Full Name zinc finger protein 611
Transcripts ENSG00000213020
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q8N823
HGNC ID HGNC:28766
VEGA ID OTTHUMG00000154908
String ID 9606.ENSP00000437616
PharmGKB ID PA134988282
Target gene [ZNF611] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5201157 chr19 34 2 36 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of ZNF611 expression and immune infiltrating cell level correlation result in HPV+ samples
ZNF611 expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of ZNF611 expression and immune infiltrating cell level correlation result in HPV+ samples
ZNF611 expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of ZNF611 expression and immune infiltrating cell level correlation result in HPV+ samples
ZNF611 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of ZNF611 expression and immune infiltrating cell level correlation result in HPV+ samples
ZNF611 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of ZNF611 expression and immune infiltrating cell level correlation result in HPV+ samples
ZNF611 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).