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HBV Target gene Detail Information

> ZNF609 Gene Search Result


Gene Information
Gene Name ZNF609
Gene ID 23060
Gene Full Name zinc finger protein 609
Transcripts ENSG00000180357
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O15014
HGNC ID HGNC:29003
VEGA ID OTTHUMG00000172370
OMIM ID 617474
String ID 9606.ENSP00000316527
PharmGKB ID PA134952302
Target gene [ZNF609] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002903 chr15 167 21 4 192 View
1002968 chr15 161 19 2 182 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ZNF609 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ZNF609 expression: Low -> High
Lollipop of ZNF609 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ZNF609 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZNF609 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF609 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).