HIV Target gene Detail Information

> ZNF518B Gene Search Result


Gene Information
Gene Name ZNF518B
Gene ID 85460
Gene Full Name zinc finger protein 518B
Transcripts ENSG00000178163
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q9C0D4
HGNC ID HGNC:29365
VEGA ID OTTHUMG00000160060
OMIM ID 617734
String ID 9606.ENSP00000317614
PharmGKB ID PA162410199
Target gene [ZNF518B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4003413 chr4 62 62 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ZNF518B expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF518B expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ZNF518B expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF518B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).