HTLV1 Target gene Detail Information

> ZNF488 Gene Search Result


Gene Information
Gene Name ZNF488
Gene ID 118738
Gene Full Name zinc finger protein 488
Transcripts ENSG00000265763
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q96MN9
HGNC ID HGNC:23535
VEGA ID OTTHUMG00000188322
String ID 9606.ENSP00000462269
PharmGKB ID PA134917840
Target gene [ZNF488] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6015441 chr10 8 3 3 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ZNF488 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF488 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).